Adolescence is a developmentally sensitive interval in which linear growth, pubertal endocrine maturation, body-composition change, and rapid skeletal mineral accrual occur while experimentation with nicotine, tobacco, and cannabis commonly begins. This critical narrative review...
Open access
Research Article10.9734/jsrr/2026/v32i94504
The intestinal microbial community assembles during the same developmental window in which adiposity, islet autoimmunity, hepatic lipid handling and linear growth are established, and this temporal coincidence has encouraged the view that microbial variation is a modifiable deter...
Open access
Research Article10.9734/jammr/2026/v38i96196
Ashraf T. Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Shayma Ahmed, Khaled A. Siddiq, Mohammed Qusad & Mohamed Alkalaf·Asian Journal of Pediatric Research·2026
Hookworm infection remains one of the most common chronic parasitic conditions of childhood in low-resource settings, and growth impairment is routinely listed among its consequences. The evidence supporting that claim is weaker and more heterogeneous than programmatic language i...
Open access
Research Article10.9734/ajpr/2026/v16i9570
Glucagon occupies an unusual position in clinical endocrinology. The same 29-amino-acid peptide serves as a provocative agent for pituitary function testing, as an emergency treatment for severe hypoglycaemia, as a continuous infusion in hyperinsulinaemic states of infancy, and,...
Open access
Research Article10.9734/jamps/2026/v28i9889
Adequate sleep is increasingly recognised as a modifiable determinant of somatic growth and endocrine function during childhood and adolescence, yet the strength and consistency of this relationship across different sleep dimensions remain incompletely resolved. This critical nar...
Open access
Research Article10.9734/ajmah/2026/v24i91421
Premature hair greying, or premature canities, is a visible, inexpensive and easily recorded phenotype that has repeatedly been proposed as an externally observable index of accelerated biological ageing. Interest in the trait extends beyond cosmetic dermatology because loss of h...
Open access
Research Article10.9734/ajrdes/2026/v9i1167
Children and adolescents receive antiseizure medications and antipsychotics for prolonged periods during the developmental window in which linear growth, bone mineral accrual, pubertal maturation and metabolic set points are established. Endocrine and auxological adverse effects...
Open access
Research Article10.9734/ajorrin/2026/v9i1192
Glycated haemoglobin (HbA1c) has become the dominant summary measure of glycaemic exposure because it is convenient, standardised and linked to long-term complication risk. Its clinical authority can nevertheless obscure a basic measurement problem: HbA1c is an indirect, time-ave...
Open access
Research Article10.9734/ijbcrr/2026/v35i51151
Schistosomiasis affects more children than any other neglected tropical disease, yet its consequences for somatic growth and endocrine function during childhood and adolescence remain less thoroughly characterised than its recognised effects on anaemia and hepatosplenic disease....
Open access
Research Article10.9734/sajp/2026/v9i3305
Maternal hypertensive disorders of pregnancy (HDP)—encompassing chronic hypertension, gestational hypertension, preeclampsia, and superimposed preeclampsia—complicate a substantial proportion of pregnancies worldwide and are increasingly recognised as determinants of offspring he...
Open access
Research Article10.9734/ajpcb/2026/v9i1219
Delayed puberty in adolescent boys arises most commonly from a self-limited maturational variant, constitutional delay of growth and puberty, but must be distinguished from permanent hypogonadotropic or hypergonadotropic hypogonadism before hormonal treatment is selected, because...
Open access
Research Article10.9734/ajrre/2026/v9i1140
Linear growth in childhood is governed by a dense network of genetic, endocrine, and environmental signals, among which nutritional status occupies a central regulatory position. Body mass index, its standardised expression as a standard deviation score, height standard deviation...
Open access
Research Article10.9734/ajpr/2026/v16i7555
Linear growth during childhood is governed by the coordinated action of the growth hormone–insulin-like growth factor-1 (GH–IGF-1) axis, yet this endocrine system does not operate in isolation from the immune system. Chronic and acute inflammatory states, whether triggered by aut...
Open access
Research Article10.9734/aji/2026/v9i1193
Background: Male reproductive dysfunction is increasingly relevant in chronic anaemias as survival into adulthood has improved in β-thalassaemia and sickle cell disease, while iron-deficiency anaemia remains globally common. Impaired fertility arises through hypoxia, oxidative st...
Open access
Research Article10.9734/ibrr/2026/v17i4392
Severe childhood obesity has become one of the more pressing public health concerns of recent decades, affecting millions of children in both high-income and low- and middle-income settings. Its metabolic and cardiovascular consequences are well documented, but a growing body of...
Open access
Research Article10.9734/ajrid/2026/v17i7559
Background: Premature ovarian insufficiency is characterised by impaired ovarian function before 40 years of age and may present in adolescents and young women with delayed puberty, primary or secondary amenorrhoea, incomplete pubertal progression, hypo-oestrogenism, and elevated...
Open access
Research Article10.9734/ajrre/2026/v9i1136
Ashraf T. Soliman, Fawzia Alyafei, Nada Mwafak Al Aaraj, Noor Sadeq Abdullah Hamed, Shayma Ahmed & Nada Soliman·Asian Journal of Pediatric Research·2026
Background: Iron deficiency anaemia (IDA) is a prevalent micronutrient disorder in childhood, with well-recognised haematological effects and increasingly reported endocrine consequences. Objectives: This review synthesised evidence on the spectrum, risk factors and reversibility...
Open access
Research Article10.9734/ajpr/2026/v16i6547
Background: Female pubertal onset is a complex, multifactorial biological event with substantial global variation. Secular trends show progressive earlier thelarche and menarche across continents, yet biochemical thresholds for diagnosing pubertal onset and central precocious pub...
Open access
Research Article10.9734/ajrre/2026/v9i1132
Ashraf Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Ahmed Elawwa, Shayma Mohamed, Noora Alhumaidy, Khalid Siddiq & Mohamed Elkalaf·Asian Journal of Pediatric Research·2026
Background: Vitamin D is traditionally characterized as a nutrient essential for calcium homeostasis. However, emerging evidence suggests that the cutaneous CYP11A1-driven secosteroid pathway serves as a "chemical proxy" for sunlight, linking environmental UV radiation to the syn...
Open access
Research Article10.9734/ajpr/2026/v16i2522
Giardiasis in childhood ranges from self-limited gastroenteritis to persistent, recurrent, or clinically silent intestinal infection. Its contribution to growth faltering remains difficult to isolate because exposure is concentrated in settings where dietary insufficiency, repeat...
Open access
Research Article10.9734/ajpr/2026/v16i8562
The developing heart is unusually exposed to the nutritional environment because it must sustain a continuously rising cardiac output while its own mass, metabolic machinery and extracellular matrix are still being assembled. Both ends of the nutritional spectrum leave a cardiac...
Open access
Research Article10.9734/jammr/2026/v38i96198