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Christopher Larbie

Publications (13)

Hydroethanolic Extracts of Ficus pumila Linn. Is Protective against Gentamicin-Induced Kidney Damage in Rats

Christopher Larbie, Portia A Siaw, Solomon Zon & Kwame Appiah-Kubi · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Ficus pumila Linn. has been reported to be rich in phenols, hepatoprotective and antiproliferative on leukemic cancer cells. The aim of this study was to evaluate the nephroprotective effect of hydroethanolic leaves extracts of F. pumila on gentamicin-induced kidney damage in rat...

Open access Research Article 10.9734/JAMPS/2018/41291

Phytochemical Constituents and Biological Activity of Fractions of Stem and Leaves of Acalypha inferno

Christopher Larbie, Felix Charles Mills-Robertson, Jasmine Naa Norkor Dowuona, Jesse John Tofah, Dennis Torkornoo & Chris Yaw Asare · Journal of Pharmaceutical Research International · 2018

Aims: Acalypha inferno is an ornamental plant which has been shown to be a phytoremediator of zinc. Other species of this genus used traditionally have been proven to possess pharmacologically active constituents. The study sought to evaluate the phytochemical constituents, in vi...

Open access Research Article 10.9734/JPRI/2017/38675

The Haematology and Serum Biochemistry of Traditional Textile Dyers in Ntonso, Kumasi were Affected by Exposure to Synthetic Textile Dyes

Osei B. Kuffour, Christopher Larbie, Afua K. A. Genfi & Richard Sedeafor · Journal of Applied Life Sciences International · 2023

Aim: To study the effects of synthetic textile dyes on haematology and serum biochemistry of traditional textile industry practitioners at Ntonso in the Ashanti region of Ghana. Study Design: Case-control study. Place and Duration of Study: The study was carried out at Ntonso in...

Open access Research Article 10.9734/jalsi/2023/v26i5620

Ethnobotany, Phytochemistry and Pharmacology of Pericopsis laxiflora (Baker) Meeuwen (Leguminosae) – A Review

Frederick Sarfo-Antwi, Christopher Larbie, Benjamin Obukowho Emikpe & Regina Appiah–Opong · International Journal of Biochemistry Research & Review · 2021

Pericopsis laxiflora (Family Leguminosae) is a medicinal plant that is ubiquitous especially in the tropical and savannah regions. There are many reports on folkloric and traditional medicinal uses that include haemorrhoids, rheumatism, abdominal pain treatment, diarrhoea, and dy...

Open access Research Article 10.9734/ijbcrr/2021/v30i230248

Extracts of Ageratum Conyzoides L. Protects against Carbon Tetrachloride – Induced Toxicity in Rats through Inhibiting Oxidative Stress

Frederick Sarfo-Antwi, Christopher Larbie & Duduyemi Babatunde · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aims: The present study was aimed at investigating the hepatoprotective and nephroprotective activities of 50% hydroethanolic leave extracts of the Ageratum conyzoides and fractions on carbon tetrachloride - induced hepatotoxicity in rats. Study Design: A total of 30 Sprague Dawl...

Open access Research Article 10.9734/JAMPS/2018/45189

The Association between Micronutrients Levels and Gestational Diabetes: A Cross Sectional Study in Ashanti Region

Daniel Abera Ataanya & Christopher Larbie · International Journal of Biochemistry Research & Review · 2018

Aims: Micronutrients such as chromium, iron, magnesium and zinc can serve as good therapeutic and preventive agents for several diabetes complications including Gestational Diabetes Mellitus (GDM). The aim of this study was to compare the serum levels of chromium, iron, zinc and...

Open access Research Article 10.9734/IJBCRR/2018/45107

Prevalence of Hypertension and Prognosis of Associated Dysfunction on Specific Organ Function among Ghanaian Adolescent Students

Abena Sekyere, Christopher Larbie, Cynthia Pomaa Asante & Odeafo Asamoah-Boakye · International Journal of Biochemistry Research & Review · 2018

Aims: To determine prevalence of hypertension among adolescent students and prognosis of associated dysfunction on specific organ function among adolescent students. Study Design: A cross-sectional study. Place and Duration of Study: Three senior high schools (SHS) in Ashanti reg...

Open access Research Article 10.9734/IJBCRR/2018/45034

Prevalence, Risk Factors and Predictors of Diabetes-related Sexual Dysfunction

Ambrose Atosona, Christopher Larbie, Marina A. Tandoh & Kwabena Nsiah · Journal of Advances in Medicine and Medical Research · 2016

Background: The prevalence and complications of diabetes are currently on the rise, so this study investigated the prevalence, risk factors and predictors of diabetic sexual dysfunction (SD). Methods: The study was cross-sectional multicentred. Patients were randomly selected fro...

Open access Research Article 10.9734/BJMMR/2016/28186

Prevalence of the Genetic Mutation CYP2C8*5 in Selected Ethnic Groups in Southern Ghana

Charles Brown, Christopher Larbie & Dominic Selorm Yao Amuzu · International Journal of Biochemistry Research & Review · 2016

Aim: The study determined prevalence of clinically relevant CYP2C8*5 polymorphism in 80 unrelated individuals, from selected ethnic groups in Southern Ghana. Medical history on adverse drug reactions of the subjects and level of dependency on drugs metabolized by CYP2C8 enzyme wa...

Open access Research Article 10.9734/IJBCRR/2016/25680

In vitro Antioxidant and Anticancer Properties of Hydroethanolic Extracts and Fractions of Ageratum conyzoides

Felix Acheampong, Christopher Larbie, Regina Appiah-Opong, Fareed K. N. Arthur & Isaac Tuffour · European Journal of Medicinal Plants · 2015

Background: Cancer is still a major public health burden in many countries and despite the research strides made in respect of therapeutic interventions, challenges still abound in cancer treatment. Ageratum conyzoides has increasingly been used in folklore for the treatment of a...

Open access Research Article 10.9734/EJMP/2015/17088

Phytochemical Constituents of Flour and Composite Bread from African Palmyra (Borassus aethiopum) Fruit from Ghana

Marian Peprah, Charles Apprey, Christopher Larbie & Odeafo Asamoah-Boakye · European Journal of Medicinal Plants · 2018

Aims: To explore the use of Borassus aethiopum fruit as composite flour and bread and determine the phytochemical composition in each product. Place and Duration: Department of Biochemistry, and Department of Food science food and sensory evaluation laboratory, between September,...

Open access Research Article 10.9734/EJMP/2018/40502

Phytochemical, Antioxidant and Safety Evaluation of Hura crepitans (L.) Stem Bark Hydroethanolic Extract in Animals

Oluwole Sunday Owojuyigbe, Caleb Kesse Firempong, Gustav Komlaga, Christopher Larbie & Benjamin Obukowho Emikpe · European Journal of Medicinal Plants · 2020

Background and Objectives: Medicinal plants have become popular in the search ofa cure for various hepatopathies with a considerable number of herbal products being used for the management of liver ailments. However, most, including Hura crepitans (HC), have not been toxicologica...

Open access Research Article 10.9734/ejmp/2020/v31i830255

Status of Some Antioxidant Micronutrient and Pregnancy Outcomes in Ghanaian Adolescents Attending Antenatal Clinic in Urban (Suntreso) and Rural (Mampong) Hospitals

Jessica Ayensu, Anthony Edusei, Ibok Oduro & Christopher Larbie · European Journal of Nutrition & Food Safety · 2017

Aims: Antioxidants are important in maintaining cellular function in normal pregnancy and are needed for mitigating the effects of oxidative stress. However, there is paucity of information on the importance of antioxidants in pregnant adolescents. This study was therefore aimed...

Open access Research Article 10.9734/EJNFS/2017/24209