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Chidi L. C. Ndukwu

Publications (8)

CRISPR-Based Diagnostics for Neglected Tropical Parasitic Diseases: A Critical Appraisal of Verified Evidence, Persistent Gaps and Pathways to Implementation in Low- and Middle-Income Countries

Chidi L. C. Ndukwu & Evelyn Orevaoghene Onosakponome · South Asian Journal of Research in Microbiology · 2026

Clustered regularly interspaced short palindromic repeats (CRISPR) nucleases with collateral, sequence-activated nuclease activity have been proposed as a route to molecular-grade sensitivity at the point of care, and the proposal is unusually consequential for neglected tropical...

Open access Research Article 10.9734/sajrm/2026/v20i10527

Detection of QnrA and QnrB Genes in Quinolone-resistant Coliform Species Isolated from Liquid, Oral Herbal Remedies

Chidi L. C. Ndukwu, Nedie P. Akani & Tonye Sampson · International Journal of Pathogen Research · 2026

Fluoroquinolones remain one of the most successful and widely exploited classes of antimicrobial agents, but recent times, widespread use of fluoroquinolones in human and veterinary medicine, as well as their presence in the water, soil, and the environment, has led to a high and...

Open access Research Article 10.9734/ijpr/2026/v15i2451

Premarital Screening for Haemoglobin Genotype, HIV and Syphilis among Prospective Couples in Port Harcourt, Nigeria

Chidi L. C. Ndukwu · International Blood Research & Reviews · 2026

Background: Premarital medical screenings for prospective marital couples are vital public health tools for the prevention of such hereditary diseases as sickle cell disease, sexually transmitted and bloodborne infections, which may be transmitted from one spouse to the other and...

Open access Research Article 10.9734/ibrr/2026/v17i1375

Demographic Variations in the Prevalence of Trichomonas vaginalis and Neisseria gonorrhoeae Infections among Females Attending Healthcare Facilities in Port Harcourt, Nigeria

Chidi L. C. Ndukwu & Ijeoma F. Ndu · South Asian Journal of Parasitology · 2024

Background: Trichomonas vaginalis and Neisseria gonorrhoeae are two pathogens of public health importance, which are sexually transmitted, highly prevalent, underdiagnosed and affecting millions of people globally. This study was aimed at finding out the prevalence of T. vaginali...

Open access Research Article 10.9734/sajp/2024/v7i4202

Microbial Communities and Antimicrobial Resistance Patterns in Aerobic Bacteria Associated with the Vaginal Microbiota: A Retrospective Study in Port Harcourt, Nigeria

Chidi L. C. Ndukwu · Asian Journal of Research in Infectious Diseases · 2024

The vaginal microbiota, unlike some other sites such as the intestinal microbiota is a less diversified micro-ecosystem; dominated normally by Lactobacilli which play specific important roles in the wellbeing of the vagina and the female person. Dysbiosis or the loss of Lactobaci...

Open access Research Article 10.9734/ajrid/2024/v15i1324

Multidrug Resistance in Klebsiella species Isolated from Liquid Herbal Remedies in Port Harcourt, Nigeria

Chidi L. C. Ndukwu & Nedie P. Akani · International Journal of Pathogen Research · 2023

Aims: Klebsiella are lactose fermenting, encapsulated, non-motile, oxidase-negative, gram negative rods; belonging to the family Enterobacteriaceae and the non-taxonomic group, coliforms. Klebsiella isolates numbering 109, recovered from three categories of liquid herbal medicine...

Open access Research Article 10.9734/ijpr/2023/v12i6256

One Health Molecular Surveillance for Emerging and Zoonotic Parasitic Diseases

Evelyn Orevaoghene Onosakponome, Chidi L. C. Ndukwu & Sonrandein Ditimi Bodensibari · South Asian Journal of Research in Microbiology · 2026

Emerging and zoonotic parasitic diseases are sustained by transmission systems that cross human, domestic-animal, wildlife, vector, food and environmental compartments. Molecular methods can reveal parasite identity, genetic diversity and connectivity across those compartments, b...

Open access Research Article 10.9734/sajrm/2026/v20i10529

Innovative Diagnostic Strategies for Neuroparasitic Diseases in Low-resource Health Systems

Esiere Rose Mary Kaiso, Chidi L. C. Ndukwu & Nathaniel Chimeka Deborah · International Journal of Pathogen Research · 2026

Neuroparasitic diseases constitute a significant but frequently overlooked component of the global burden of neurological disorders and disproportionately affect populations in low- and middle-income countries. This review evaluates current and emerging diagnostic strategies for...

Open access Research Article 10.9734/ijpr/2026/v15i5487