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Charles C. Nwafor

Publications (6)

Evaluation of Fleurya aestuans Extract against Brewer’s Yeast and Egg Albumin Induced Pyrexia and Inflammation

Charles C. Nwafor, Kiridi E. Gabriel & Solomon M. Uvoh · Asian Journal of Research and Reports in Neurology · 2022

The goal of this study is to see if hydroethanolic extract of Fleurya aestuans can reduce pyrexia and inflammation in Wistar rats. 50 study animals were divided into two groups: Pyrexia group (1, 2, 3, 4) and Inflammatory group (A, B, C, D and E). Fever was produced in the resear...

Open access Research Article

Effect of Hydroethanol Leaf Extract of Fleurya Aestuans on Histological and Renal Function Test of an Alloxan Induced Diabetic Wistar Rats

Charles C. Nwafor, Osakwe F. Uchechwukwu, Mfonido G. Umanah, Ekikereabasi P. Inyang & Peters K. Dell · International Journal of Advances in Nephrology Research · 2022

Aim: To examine the effect of Fleurya aestuans extract (FAE) on histological and renal function test (RFT) in an alloxan-induced type 2 diabetes rat model. Study Design: The experiment was conducted in the department of Human Physiology, Madonna University, Nigeria, between Augus...

Open access Research Article

Fleurya Aestuans Leaves and Tetrahydroxyflavone Mitigate Lead Induced Testicular Toxicity in Wistar Rats

Charles C. Nwafor, Ifedi I. Charles, Ekikereabasi P. Inyang, Solomon M. Uvoh, Okache B. Ogwihi & Alagha B. Ebiyemzi · Journal of Advances in Medical and Pharmaceutical Sciences · 2021

The effects of Fleurya aestuans leaves and tetrahydroxyflavone on the reproductive functions of lead acetate induced testicular toxicity in Wistar rats was investigated in this study. The study animals were divided into control group (A) and toxicity-induced groups (B, C, D, E, F...

Open access Research Article 10.9734/jamps/2021/v23i1030265

Technology-assisted Neurobehavioral and Histomorphometric Assessment of Chronic Lead and Cadmium Exposure in an Animal Study

Ndubuisi F. Nwodo, Charles C. Nwafor, Okafor K. Oluchi, Ifedi I. Charles, Jacob A. Akpan & Felix O. Ogbo · Biotechnology Journal International · 2026

Backgrounds: Heavy metals like lead (Pb) and cadmium (Cd) are toxic environmental pollutants that cause serious health effects, particularly neurotoxicity, organ damage, and carcinogenic risks. Their combined exposure can enhance toxicity through synergistic interactions, increas...

Open access Research Article 10.9734/bji/2026/v30i2867

Attenuation of Reproductive Dysfunctions by Hydroethanolic Leaf Extract of Fleurya aestuans in Diabetic Rats

Green I. Kinikanwo, Charles C. Nwafor & Weleh I. Iyke · Asian Research Journal of Gynaecology and Obstetrics · 2021

Diabetes mellitus produces excessive reactive oxygen species (ROS) in the male gonads resulting to impairments of steroidogenesis and spermatogenesis. Fleurya aestuans is an extremely basic plant with therapeutic properties but it’s frequently viewed as a weed in Nigeria. The pre...

Open access Research Article

Apoptotic and Structural Changes in Lungs Tissues of Toluene Induced Respiratory Injury in Wistar Rats

Michael O. Onyewuchi, Ovie F. Ogbo, Charles C. Nwafor, Oliver N. Lilian & W. Ikpama · Asian Journal of Research in Nursing and Health · 2022

To investigate the impact of toluene exposure on the functional-morphology of the pulmonary tissues, 35 Wistar rats were acquired. The study was divided into three (3) groups: A, B, and C, with three (3) phases: acute (7 days), subchronic (14 days), and chronic (21 days). Group A...

Open access Research Article