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Asogwa Felix Keneolisa

Publications (7)

Membrane Stabilization, PhospholipaseA2, Albumin Denaturation, Protease Inhibition, as Viable Mechanisms for the Anti-Inflammatory Effects of Methanol Extract of Rauvolfia vomitoria Afzel Leaves

Ugwu Obiora Celestine, Asogwa Felix Keneolisa, Ukpabi-Ugo Jacinta Chigozie, Asadu Chidimma Lilian, Ali Ibeabuchi Jude, Okonkwo Raymond Maduabuchi, Ugwoke Faith Ifeanyi, Offiah Raymond Ogbonna, Obasi Uchenna Emmanuel & Anosike Chioma Assumpta · Asian Journal of Research in Biochemistry · 2023

Background: The body uses inflammation as a defence mechanism to eliminate harmful stimuli like germs, damaged cells, or irritants and to initiate the healing process. However, the ongoing discovery of several medicinal plants and the testing of their bioactivity to produce infor...

Open access Research Article 10.9734/ajrb/2023/v13i3260

Evaluation of Anti-Diabetic Property of Methanol Extract of Ficus Exasperata Vahl. (Moraceae)

Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Offiah Raymond Ogbonna, Okonkwo Raymond Maduabuchi & Nwobodo Ebenezer Ugochukwu · Advances in Research · 2022

Background: Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from impairments in insulin secretion, insulin action or both. The side effect of orthodox is alarming and expensi...

Open access Research Article 10.9734/air/2022/v23i5911

Anti-inflammatory Assessment of Methanol Extract of Acalypha ciliata Leaves and It’s Leucocyte Mobilization in Adult Wistar Rats

Ugwu Obiora Celestine, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Ukpabi-Ugo Jacinta Chigozie, Omeh Romanus Chijioke, Okonkwo Raymond Maduabuchi, Ugwoke, Faith Ifeanyi, Offiah Raymond Ogbonna & Anosike Chioma Assumpta · European Journal of Medicinal Plants · 2023

Aim: The study's objective was to examine the anti-inflammatory activity and leucocyte mobilization of a methanol extract of leaves from Acalypha ciliata in adult Wistar rats. Study Design: Egg albumin-induced edema was used for anti-inflammatory test and leucocyte mobilization t...

Open access Research Article 10.9734/ejmp/2023/v34i41132

Evaluation of the Anti-inflammatory Effects of Methanol Extract of Rauwofia vomitera Leaves (MERVL) Using In-vivo Based Assays

Ugwu Obiora Celestine, Ukpabi-Ugo Chigozie Jacinta, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Ugodi Gerald Walter, Obasi Uchenna Emmanuel, Ogbonna Chidera Gloria, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2024

Background of the Study: The response of the body to harmful stimuli, such as tissue damage or a pathogenic infection is known as inflammation.  Rauwofia vomitera is a medicinal plant that is native to large areas of tropical Africa and it belongs to the family of Apocynaceae. It...

Open access Research Article 10.9734/ijbcrr/2024/v33i5877

Effect of Ethyl Acetate Fraction of Terminalia ivorensis on Ethanol Induced Infertility in Male Rats

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Ude Ogochukwu Presca, Adonu Cyril Chekwube, Asogwa Felix Keneolisa, Uzoefuna Chima Casmir, Idokoja Levi Onyebuchi, Nwokedi Chukwuebuka Kingsley, Offia Ogbonna Raymond & Anosike Chioma Assumpta · Asian Journal of Research in Biochemistry · 2025

Background: This research investigates the Effect of Ethyl Acetate Fraction of Terminalia ivorensis on Ethanol Induced Infertility in Male Rats. Infertility is the inability to conceive after one year of unprotected intercourse for couples under 35, or after six months for those...

Open access Research Article 10.9734/ajrb/2025/v15i1347

Assessment of the Potential Mechanisms of Anti-diarrhoeal Activities of Ethanol Extract of Monoon longifolium Leave in Wistar Rat

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Asadu Chidinma Lilian, Ali Ibeabuchi Jude, Asogwa Felix Keneolisa, Uzoefuna Chima Casmir, Ogbu Chukwudi Collins, Nwokedi Chukwuebuka Kingsley & Anosike Chioma Assumpta · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Background: Numerous diseases related to diarrhea are the primary cause of morbidity and mortality in underdeveloped countries, accounting for hundreds of thousands of deaths annually. Polyalthia longifolia, the false ashoka, commonly referred to as Monoon longifolium is a tree s...

Open access Research Article 10.9734/jamps/2024/v26i9713

Phytochemical Screening and Ameliorative Potential of Ethyl Acetate Fraction of Polyaltha logifolia Leaves on Croton Oil-induced Hemorrhoid in Albino Wistar Rats

Ugwu Obiora Celestine, Umeakuana Chidinma Doris, Ogbonna Chidera Gloria, Uzoefuna Chima Casmir, Onyima Glory Chinemerem, Adonu Cyril Chekwube, Asogwa Felix Keneolisa, Omeh, Chijioke Romanus, Idokoja Levi Onyebuchi, Offia Ogbonna Raymond, Onah Benjamin Emenike, Pete Princess Oluchukwu & Anosike Chioma Assumpta · International Journal of Biochemistry Research & Review · 2025

Background: Hemorrhoids are a very common anorectal condition defined as the symptomatic enlargement and distal displacement of the normal anal cushions. Aim: The research is aimed at investigating the ameliorative potential of ethyl acetate fraction of Polyaltha logifolia leaves...

Open access Research Article 10.9734/ijbcrr/2025/v34i2959