Upstreaming and Downstreaming Regulators and Associated Signaling Transduction Pathways of AKT/PKB: A Molecular Gateway to Progressive Carcinoma
Abu Sayed, Md. Hasibul Hossain, Efaaj Islam & Md. Ali Asgar · Asian Journal of Biology · 2023
AKT or Protein Kinase B, the serine/threonine-specific protein kinase, is found in three analogous isoforms in cells of human and animal bodies. AKT is regulated and activated via various upstream regulators including GPCR (G protein-coupled receptor), RTK (Receptor tyrosine kina...