Aim: To investigate the effect of Carica papaya seed extract on KBrO3 - induced nephrotoxicity in rats. Renal toxicity was induced by a single oral dose of 100 mg/kg body weight of KBrO3. Study Design: Thirty (30) male albino rats were divided into six groups, five rats per group...
Open access
Research Article10.9734/ajbgmb/2019/v2i130051
Kidney dysfunction in orthopaedic cases may be as a result of kidney injury due to fracture, burns, osteomyelitis, spinal injury, spinal tuberculosis, sickle cell disease and various forms of arthritis. This study aimed at evaluating the biomarkers of kidney dysfunction among pat...
Open access
Research Article10.9734/JAMMR/2017/31640
Aim: In the present study, the alkaloid, flavonoid and saponin-rich extracts of the leaves and seeds of Moringa oleifera were partially-purified and the ACE inhibitory activities and patterns of inhibition determined. Methodology: Alkaloids, flavonoids and saponins were extracted...
Open access
Research Article10.9734/JABB/2016/21974
The use of medicinal plant to prevent and or cure liver problems is a practice not peculiar to developing countries. This research work evaluated oral LD50 and hepatoprotective properties of aqueous stem bark extract of Khaya senegalensis (ASBEKS) in rats. The rats were grouped i...
Open access
Research Article10.9734/BJAST/2015/16545
Aim: The protective effect of some selected vegetables {Moringa (Moringa oleifera), Cabbage (Brassica oleracea) and Tomato (Solanum lycopersicum)} against hepato- cardio toxicity of halofantrine (an antimalarial drug) was evaluated in 72 albino rats. Study Design: The rats were g...
Open access
Research Article10.9734/BJPR/2014/7644
Background: Okra fruits have been found to be efficient in managing hyperlipidemia. But, there are different varieties of Okra, and whether antihyperlipidemic efficiency varies with the varieties has not been reported. Aim of the Study: The aim of the study was to validate antihy...
Open access
Research Article10.9734/jalsi/2020/v23i730174
A. Nasir, M. S. Sule, A. J. Alhassan, A. M. Wudil, A. A. Imam, A. Idi, I. U. Muhammad, A. I. Yaradua, K. I. Matazu & A. M. Kanadi·Annual Research & Review in Biology·2020
The present study was conducted to evaluate anti-diabetic potentials of column chromatography fractions (F1-F6) of chloroform leaf extract of Ficus polita and to detect the probable bioactive compounds present in the most active fraction using spectroscopic techniques. Antidiabet...
Open access
Research Article10.9734/arrb/2020/v35i730251
A. J. Alhassan, I. U. Muhammad, M. S. Sule, A. M. Wudil, A. A. Imam, A. Idi, A. Muhammad, A. Mohammed, I. Alexander & A. Nasir·Annual Research & Review in Biology·2017
Khaya senegalensis A. Juss (Meliaceae), is regarded as the most popular medicinal meliaceous plant. The present study was conducted to evaluate anti-diabetic potentials of column chromatography fractions (FI-FVII) from ethyl acetate extract of Khaya senegalensis stem bark and det...
Open access
Research Article10.9734/ARRB/2017/35908
Oral LD50 and hypoglycemic activity of aqueous fruit pulp extract of Adansonia digitata L. (AFPEAD) were investigated in this research. A total of fourty eight (48) rats were used, twelve (12) of the rats were used for oral LD50 determination, and were grouped into four (4) group...
Open access
Research Article10.9734/JAMPS/2016/23862
Aim: To investigate the effect of the chromatographic fractions of Carica papaya seed on KBrO3 –induced reduction in the activities of renal brush border membrane (BBM) marker enzymes and the changes in activities of some enzymes of carbohydrate metabolism in the kidney of rats....
Open access
Research Article10.9734/ajbgmb/2021/v8i430198
Partial-purification and Characterization of Angiotensin Converting Enzyme Inhibitory Proteins from the Leaves and Seeds of Moringa oleifera Aim: To partially-purify, characterize and investigate the inhibition pattern of proteins from the leaves and seeds of Moringa oleifera. Me...
Open access
Research Article10.9734/IJBCRR/2015/12065
Aim: To evaluate the effect and identify the bioactive constituents of Carica papaya seed with potency against potassium bromate –induced nephrotoxicity and oxidative stress in renal tissue of rat. Study Design: For each state of polarity, twenty male Wistar rats were divided int...
Aim: To investigate the effect of five extraction solvents of varying polarity, namely aqueous, methanol, ethyl acetate, chloroform and n-hexane on phytochemicals yield and composition of Carica papaya seed. The acute toxicity test of each solvent fraction was also carried out an...