Background: Infective endocarditis is still a frequent, life-threatening condition, despite advances in diagnosis and treatment. It can occur in a healthy heart, but more often in a pathological heart, as the congenital heart disease without surgery, or with a residual shunt or p...
Pulmonary aneurysms are rare abnormalities of the pulmonary vessels that are often associated with pulmonary hypertension. However, the occurrence and treatment of this pathology are still unclear. A 33-year-old patient with a medical history of transcutaneous mitral commissuroto...
Aortic complications in Marfan syndrome can be life-threatening, yet this case uniquely illustrates the catastrophic consequences of delayed diagnosis in a young patient. We report a 21-year-old man with a family history of Marfan syndrome who presented with acute dyspnea and tea...
Open access
Research Article10.9734/ajrcd/2026/v8i1156
Background: This study reports the case of a 47-year-old woman who presented with acute pain and coldness in the left lower limb, occurring 5 months after a surgical closure of an atrial septal defect (ASD). Initial examination suggested acute limb ischemia. Methods: Doppler ultr...
Open access
Research Article10.9734/ca/2024/v13i4444
Libman-Sacks endocarditis (LSE), characterized by the formation of verrucous vegetations, is a typical cardiac manifestation of autoimmune diseases such as systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). It primarily leads to cardiac valve lesions. The mos...
Haless Kamal, Jama Dounia, Boucetta Abdoullah, R. HABBAL, A. DRIGHIL, L. Azouzi, G. Benouna, S. AROUS & M. HABOUB·Asian Journal of Cardiology Research·2023
Background: Thromboembolic disease is the third leading cause of cardiovascular death. In recent years, several lines of evidence have indicated the possibility of de novo thrombus generation in pulmonary arteries without deep vein thrombus (DVT) in the lower extremities. Pulmona...
Background: Wolff–Parkinson–White (WPW) syndrome is a cardiac conduction disorder characterized by the presence of an accessory atrioventricular pathway responsible for ventricular pre-excitation and predisposition to supraventricular tachyarrhythmias. Although frequently diagnos...
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Research Article10.9734/ajcr/2026/v9i1370
D. Bennani, A. El Bouazizi, L. Afendi, F. Essadqi, M. HABOUB, A. DRIGHIL, K. Gourram, Y. Sakhy, H. Tabakh, A. Siwane, N. Touil & O. Kacimi·Asian Journal of Cardiology Research·2026
We report the case of an acute embolic-appearing ischemic stroke that led to the diagnosis of a complex aortic pathology combining an ascending aortic aneurysm, defined as a permanent pathological dilation of the proximal aorta conferring a major risk of dissection or rupture, an...
Open access
Research Article10.9734/ajcr/2026/v9i1361
Pericardial effusion, while not uncommon, poses significant diagnostic and therapeutic challenges, particularly when presenting as tamponade, especially in young individuals without identifiable risk factors. We present a compelling case of a 19-year-old with acute dyspnea ultima...
Background: Dextrocardia is a rare congenital condition characterized by right-sided cardiac positioning, which may complicate electrocardiographic interpretation and coronary angiography. In patients presenting with non–ST-elevation myocardial infarction, subtle or absent ST-seg...
Open access
Research Article10.9734/ajcr/2026/v9i1377
Myocarditis is one of the most varied syndromes seen in cardiovascular medicine, being diagnosed as a self-limited inflammatory injury with rapid resolution of symptoms, to fulminant cardiogenic shock, malignant arrhythmias and chronic inflammatory cardiomyopathy, as well as sign...
Open access
Research Article10.9734/ajrimps/2026/v15i2386
Background: Left ventricular hypertrophy due to hypertension (LVH) is one of the most important cardiac manifestations of chronic hypertension and is strongly associated with heart failure, atrial fibrillation, stroke, and death. While traditionally thought of as an adaptive resp...
Open access
Research Article10.9734/ajrimps/2026/v15i2381
Cardiac magnetic resonance imaging, more precisely cardiovascular magnetic resonance (CMR), has moved from a predominantly morphological tool to a comprehensive method for myocardial tissue characterisation, perfusion assessment, and risk stratification. Its strongest contemporar...
Open access
Research Article10.9734/ajcr/2026/v9i1358
F. El Hachimi, L. Laklalech, S. SAADAOUI, M. BOUZIANE, M. HABOUB, O. AISSAOUI, A. DRIGHIL, S. KALOUCH & R. HABBAL·Asian Journal of Cardiology Research·2025
Background: MDMA (3,4-methylenedioxymethamphetamine) intoxication in children is rare but potentially life-threatening. While neurotoxicity is better documented, cardiotoxicity in infants remains underreported. Case: Seizures in infants can have various causes, including febrile...
Open access
Research Article10.9734/ajcr/2025/v8i1300
Left atrial myxomas are rare but potentially serious tumors capable of causing systemic embolism and obstructive cardiac symptoms. We report the case of a 56-year-old woman with cardiovascular risk factors who was admitted for an acute ischemic stroke. Investigations revealed a l...
Open access
Research Article10.9734/ajcr/2025/v8i1285
We report the case of a 20-year-old woman admitted to the cardiology intensive care unit for acute heart failure. Initial evaluations suggested hypertrophic cardiomyopathy (HCM), but cardiac magnetic resonance imaging (MRI) revealed diffuse myocardial fibrosis and features consis...
Open access
Research Article10.9734/ajcr/2025/v8i1281
Background: Pericardial effusion, though uncommon, poses a significant threat to patient well-being, particularly when associated with underlying malignancies such as breast cancer recurrence. Timely recognition and intervention are crucial for improved prognosis and patient outc...
Open access
Research Article10.9734/ijmpcr/2024/v17i2379
Direct oral anticoagulants are used in the management and prophylaxis of venous thromboembolism (VTE) and other thrombotic diseases including non-valvular atrial fibrillation. The most serious complication of DOAC agents is bleeding, dominated by gastrointestinal hemorrhages, eve...
Open access
Research Article10.9734/ca/2023/v12i4382
Background: Isolated pulmonary valve endocarditis (PVE) is a rare condition that accounts for 1.5–2% of all reported cases of endocarditis. Herein, we describe a rare case of isolated pulmonary valve endocarditis with a fortuitous discover of a congenital heart disease in a young...
Open access
Research Article10.9734/ca/2023/v12i4362
H. Bendahou, M. Njie, Y. Ettagmouti, M. HABOUB, S. AROUS, G. Bennouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2023
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is arare inherited cardiac disease that presents with progressive right ventricular (RV) dysfunction due to fibro-fatty replacement of the myocardium and associated with an elevated risk of ventricular arrhythmias...
The aim of this case report is to draw attention at the potential severity of presentation of these associated pathologies. Prevention through early screening of colorectal cancer in patients with coronary artery disease and vice versa is the guarantee of a better management of t...
Open access
Research Article10.9734/ca/2023/v12i3335
Background: Pacemaker (PM) devices are increasingly used to treat cardiac conduction abnomality especially in elderly population. Twiddler syndrome (TS) in PM patients is a condition where patient manipulation of a pacemaker leads to its retraction and dysfunction. TS can be extr...
Background: Ischemic stroke following thrombolysis for ST-segment elevation myocardial infarction(STEMI) is a rare and perplexing complication. We present an intriguing case of ischemic stroke following fibrinolytic therapy with tenecteplase for a STEMI. This is an extremely rare...
Open access
Research Article10.9734/ca/2022/v11i4303
Introduction: The occurrence of venous thrombosis in children is rare, often idiopathic and rarely a known etiology can be found, with sometimes a delay diagnostic in most cases. Method: We report a case illustrating the difficulties of diagnosing phlebitis and a fairly rare eti...
P. M. Mulendele, M. Charfo, M. Njie, B. E. Ovaga, A. Salim, Med G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Background: Myocardial bridging (MB) is a congenital coronary anomaly with normal coronary epicardial artery taking an intra myocardial pathway also described as tunneled artery. This benign anatomical abnormality usually can manifest as an acute coronary syndrome or fatal ventri...
Coronary perforation is an uncommon yet potentially fatal complication associated with percutaneous coronary intervention (PCI). Distal wire perforations may rapidly lead to cardiac tamponade and hemodynamic collapse if not promptly recognised and treated. The Study reports a cas...
Open access
Research Article10.9734/ajcr/2026/v9i1375
Pulmonary Embolism (PE) remains a relevant source of morbidity in women of reproductive age, although it is often unrecognized. Hormonal contraception is a well-established acquired risk factor for PE because of its association with venous thromboembolic events; however, it has v...
Open access
Research Article10.9734/ajrimps/2026/v15i2379
Background: Iron deficiency is a common comorbidity in patients with heart failure. This association is often underrecognized in clinical practice, despite its important implications for symptoms and prognosis. Iron deficiency has been associated with worse symptoms, impaired fun...
Open access
Research Article10.9734/ca/2026/v15i2531
Background: Caseous calcification of the mitral annulus (CCMA) is a rare variant of mitral annular calcification characterized by liquefaction necrosis within chronically calcified annular tissue. Its pseudotumoral appearance may mimic cardiac tumors or infective processes, creat...
Open access
Research Article10.9734/ajrcd/2026/v8i1149
We report the case of a 44-year-old man, a chronic smoker with a 28 pack-year history, regular consumer of alcohol, cannabis, and hashish, followed for coronary artery disease and having undergone two angioplasties, who was admitted for typical chest pain with ST-segment elevatio...
Open access
Research Article10.9734/ajcr/2026/v9i1357
A. MOUNSSIF, B. ELKABLI, Z. MOULAY RCHID, M. BOUZIANE, M. HABOUB, S. AROUS, EM. BENOUNA, A. DRIGHIL & R. HABBAL·Asian Journal of Medicine and Health·2025
Background: Polyarteritis nodosa (PAN) is a rare necrotizing vasculitis affecting medium-sized arteries. While cardiac involvement is uncommon, it can lead to severe coronary complications. We report a case of hepatitis B virus-associated PAN (PAN-HBV) revealed by an acute ST-e...
Open access
Research Article10.9734/ajmah/2025/v23i61255
Ventricular septal rupture (VSR) is an uncommon but well-recognized mechanical complication of acute myocardial infarction (MI). Mortality without intervention is 70% in intrahospital at 30 days, and 90% at one year due to cardiogenic shock. Transthoracic echocardiography (TTE) i...
Open access
Research Article10.9734/ca/2024/v13i1400
Cardiac papillary fibroelastoma is histologically a benign endocardial neoplasm. Though CPF has long been reported as the second most common primary cardiac neoplasm, it has since been pulled ahead of cardiac myxomas, largely due to evolving cardiac imaging modalities. We present...
Open access
Research Article10.9734/ca/2023/v12i4378
Carbon monoxide (CO) intoxication is the most frequent etiology of toxicological morbidity and mortality in the world. If the neurological manifestations are in the foreground, then cardiovascular signs of myocardial damage by necrosis are possible, which can result in angina, an...
Open access
Research Article10.9734/ca/2023/v12i4370
Vitamin k antagonist anticoagulants (VKAs) and non-vitamin K oral anticoagulants (NOACs) are widely used in the treatment of non-valvular atrial fibrillation and other indications, but both classes of medications carry a risk of potentially serious bleeding. Spontaneous hematoma...
Open access
Research Article10.9734/ca/2023/v12i4365
K. Chawki, E. M. Rochd, M. Selmaoui, A. El Jazouli, M. HABOUB, S. AROUS, G. Bennouna, A. DRIGHIL & R. HABBAL·Asian Journal of Cardiology Research·2023
We report a rare case of a patient who despite being under anti VEGF : Bevacizumab , developed a large coronary collateral circulation completely supplying the chronic total occlusion of left main coronary artery. Bevacizumab, a monoclonal antibody was the first potent angiogenic...
AA amyloidosis is a classic and serious complication of many chronic inflammatory processes, whether of infectious, autoimmune, or neoplastic origin. It is frequently complicated by kidney damage, often in the form of a nephrotic syndrome. Giant cell arteritis is a common inflamm...
Open access
Research Article10.9734/ca/2023/v12i4353
H. Bendahou, M. Njie, S. Zahri, A. Abouriche, M. HABOUB, S. AROUS, G. Bennouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2023
The saccular aneurysm at the level of the ascending aorta is an extremely rare clinical entity, considered as an effusion of part of the aortic circumference. This entity is often asymptomatic, and the pathophysiological mechanism is still poorly understood. We describe two unusu...
Hypertrophic cardiomyopathy (HCM) is the most common non-ischemic cardiomyopathy with a prevalence of 1:500 in the general population, based on the recognition of the phenotype. HCM is defined by the presence of increased left ventricular (LV) wall thickness that is not solely ex...
Open access
Research Article10.9734/ca/2023/v12i4342
LVNC (left ventricular non-compaction) is a rare congenital cardiomyopathy with a reported incidence of 0.05% in adults. It can occur in isolation or affect both ventricles. It’s characterized by prominent LV trabeculae and deep intertrabecular recesses which are filled with bloo...
Open access
Research Article10.9734/ca/2023/v12i3319
M. Njie, H. Bendahou, P. M. Mulendele, M. B. Charfo, M. HABOUB, S. AROUS, M. Ghali Benouna, A. DRIGHIL, L. Azouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Rheumatic mitral stenosis (MS) remains the most common type of valvular heart disease worldwide. While the prevalence of mitral valve rheumatism is decreasing in industrialized countries, it continues to be endemic in most countries in Asia, Latin America, the Middle East and Afr...
Acute aortic dissection on bicuspid aortic valve (BAV) type 0 is a rare especially in young masculine. Risk factors like smoking and intensive sport activities can hasten their apparition especially in non-diagnosed population. Trans thoracic echocardiography is very important in...
Open access
Research Article10.9734/ca/2022/v11i4297
L. Laklalech, M. Njie, A. Abourich, M. Belhakim, M. HABOUB, S. AROUS, Med G. Bennouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Serpentine thrombus or snake like floating thrombus of the right-side cavities of the heart is a rare diagnosis. Its an extreme emergency, and is often fatal due to the migration of small thrombus which can completely obstruct the pulmonary trunk. Advanced cancer disease is one o...
M. Njie, B. E. Ovaga, S. I. Harouna, H. Hatim, M. HABOUB, A. Salim, Med G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Pulmonary embolism (PE) is a common condition characterized by clinical polymophism making its diagnosis difficult. Syncope as an initial symptom of pulmonary embolism has proven to be a difficult clinical correlation to establish, although described in the literature. It is more...
M. Njie, A. El Jazouli, P. M Mulendele, M Charfo, M. HABOUB, A. Salim, Med G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Bupivacaine (marcaine) is a long-acting local anesthetic used for skin infiltration, peripheral nerve blocks, epidural and spinal anesthesia. Its application can lead to cardiovascular complications such as: hypotension, bradycardia, cardiac arrest and toxic myocardial injury. Fe...
Background: Acute pulmonary embolism (PE) constitutes a leading cause of illness and death from cardiovascular disease around the world. Even with better ways to diagnose and treat PE, it is still difficult to manage, especially in places where local data are limited. In Morocco,...
Open access
Research Article10.9734/ca/2026/v15i2533
Background: Right-sided infective endocarditis (IE) is uncommon, accounting for only 5–10% of cases, and is typically associated with intravenous drug use or intracardiac devices. Streptococcus pneumoniae has become a rare cause of IE, especially on the tricuspid valve. Early dia...
Open access
Research Article10.9734/ajrcd/2026/v8i1147
A. El Bouazizi, D. Bennani, L. Afendi, S. Essadqi, M. HABOUB, M. BOUZIANE, S. AROUS, G. Benouna & A. DRIGHIL·Asian Journal of Cardiology Research·2025
Aims: To emphasize that acute alcohol consumption may provoke transient sinoatrial or atrioventricular conduction disturbances leading to syncope in otherwise healthy young adults, and to advocate for prolonged electrocardiographic monitoring in such settings. Presentation of Cas...
Open access
Research Article10.9734/ajcr/2025/v8i1339
Acute coronary syndromes (ACS) are major cardiovascular emergencies requiring prompt and appropriate management to reduce complications and improve prognosis. We report an unusual case of high-risk non-ST-segment elevation myocardial infarction (NSTEMI) in a 63-year-old patient w...
Open access
Research Article10.9734/ca/2025/v14i2489
Background: APECED or multiple endocrine deficiency autoimmune candidiasis syndrome is a rare disease characterized by the manifestation of autoimmune endocrinopathies in a peculiar sequence during infancy. The clinical diagnosis of APECED requires the presence of at least two of...
Open access
Research Article10.9734/jocamr/2024/v25i7544
Arrhythmogenic right ventricular cardiomyopathy is a genetic disease that affects young people. As its name indicates, it carries a risk of ventricular rhythm disturbances and sudden death, particularly during sporting efforts emphasizing the need for early diagnosis of the disea...
Open access
Research Article10.9734/ca/2024/v13i2411
Reports of thrombi straddling the patent foramen ovale (PFO) are uncommon occurrences. The development of thrombi within the cardiac chambers poses a greater risk of mortality compared to pulmonary embolism (PE) alone and may necessitate a change in treatment strategy [1]. In thi...
Takayasu's disease is the first cause of inflammatory aortitis in young subjects. The disease preferentially affects the women. Takayasu's disease could be a mode of non-specific reaction of the aorta to various infectious or dysimmune etiological factors. Aortic insufficiency i...
Open access
Research Article10.9734/ca/2023/v12i4341
Drugs used to treat cardiovascular disease as well as those used in the treatment of multiple other conditions can occasionally produce exaggerated prolongation of the QT interval on the surface electrocardiogram and the morphologically distinctive polymorphic ventricular tachyca...
Open access
Research Article10.9734/ca/2023/v12i3327
N. Mahoungou-Mackonia, Brahim Nassour, A. Maaroufi, Fadoul Adam, Harouna Seydou, I. Nouamou, S. AROUS, G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Cardiology Research·2021
Echinococcosis is a parasitosis that is endemic in many parts of the world. Cardiac involvement is rare at (˂ 3%) or 0.5-2% of all cardiac involvement let alone right chamber involvement. We have reported a case of a 15 year old girl with echinococcosis of the right ventricle in...
Background: Acute pulmonary embolism (PE) is a major cardiovascular emergency associated with substantial morbidity and mortality, particularly when diagnosis is delayed. Because the clinical spectrum varies widely (mild dyspnea to near-cardiac collapse), it is important for clin...
Open access
Research Article10.9734/ca/2026/v15i2535
Background: Acute aortic regurgitation is an uncommon but life-threatening complication of infective endocarditis. It results from rapid destruction of the aortic valve or extension of infection to surrounding structures, leading to abrupt hemodynamic deterioration that often req...
Open access
Research Article10.9734/ca/2026/v15i2534
Background: Infective endocarditis remains a life-threatening disease with significant morbidity and mortality. Acute aortic regurgitation is among the most severe complications of infective endocarditis and results from rapid destruction of the aortic valve apparatus. This condi...
Open access
Research Article10.9734/ajrcd/2026/v8i1151
We report a rare case of inverted Takotsubo syndrome in a 24-year-old woman. Takotsubo syndrome, also known as stress cardiomyopathy or broken heart syndrome, is a transient condition characterized by acute and reversible dysfunction of the left ventricle. Cardiac auscultation sh...
Vasospastic angina (VSA), initially described by Prinzmetal as a form of angina occurring at rest, in the second part of the night and associated with transient changes in repolarization such as ST segment elevation on the electrocardiogram. The phenomenon of coronary spasm can o...
Open access
Research Article10.9734/ca/2024/v13i2403
P. M. Mulendele, M. Njie, M. B. Charfo, G. M. Lukifimpa, M. S. Boutar, B. E. Ovaga, M. HABOUB, S. AROUS, M. G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Cardiology and Angiology: An International Journal·2023
The emergence of immunotherapy and the gradual expansion of its indications in oncology will require particular vigilance to detect and quickly take care of the potential cardiac toxicities. They have improved prognosis and survival, including patients with kidney, lung or skin c...
Open access
Research Article10.9734/ca/2023/v12i4360
N. Mahoungou- Mackonia, Harouna Seydou, Brahim Nassour, Njei Malick, Fadoul Adam, Ovaga Esther, I. Nouamou, S. AROUS, G. Benouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Research in Cardiovascular Diseases·2020
It has been reported that hyperthyroidism could be the cause of arrhythmias at the ventricular and supraventricular levels, while conduction disorders are very rarely described. We report through our observation the case of a 45-year-old patient diagnosed with atrioventricular bl...
F. Karim, I. Tlohi, N. Mahoungou-Mackonia, Y. Hamine, H. Seydou, M. Njie, C. B. Mahamadou, M. HABOUB, S. AROUS, G. Benouna, A. DRIGHIL, L. Azouzi & R. HABBAL·Asian Journal of Cardiology Research·2022
Left ventricular pseudoaneurysms are rare. They are usually form from a rupture of the myocardium contained by pericardial adhesions. Unlike true aneurysms, false aneurysms have a narrow neck and lack myocardial elements. They can be constituted spontaneously or acquired. We repo...
N. Mahoungou- Mackonia, M. El Mousaid, A. El Amraoui, A. Fadoul, Harouna Seydou, Brahim Nassour, Ovaga Esther, I. Nouamou, S. AROUS, G. Bennouna, A. DRIGHIL, L. Azzouzi & R. HABBAL·Asian Journal of Research in Cardiovascular Diseases·2021
Infectious endocarditis is an infrequent but serious disease with multiple complications, as reported by the European society of cardiology in 2015. Rheumatic manifestations are some of the frequently encountered but rarely described complications. Even less described is the poly...