Aim: A comparative evaluation of the physicochemical and in vitro dissolution properties of metformin hydrochloride tablet brands sampled in five cities in Ghana was undertaken to assess their pharmaceutical equivalence. Place and Duration of Study: Department of Pharmaceutics, K...
Open access
Research Article10.9734/bjpr/2016/21862
Aims: Highly Active Antiretroviral Therapy (HAART) is associated with metabolic complications. An unexpected extension of functional implications of melatonin, the neuro-hormone synthetized during the night, has been reported on the development of type 2 diabetes, sleep disturban...
Open access
Research Article10.9734/bjpr/2016/29474
Aims: This study was aimed to evaluate the potential of using Raphia hookeri gum as a binder in tablet formulations. Study Design: Extract of Raphia hookeri gum was investigated as a binding agent in paracetamol tablet formulation in comparison with gelatin BP as standard binder....
Open access
Research Article10.9734/bjpr/2016/28610
Aims: This paper mentions of the investigation of the enzymes binding to Voglibose and the choice of the enzyme which is suitable for drug enzyme interaction as used in biosensing. Voglibose is an antidiabetic drug which is reactive and hence used in very low concentrations. The...
Open access
Research Article10.9734/bjpr/2016/30369
Purpose: To develop a highly selective, reproducible & precise rugged bio analytical method for estimation of Bortezomib (BTZ), “A Protease Inhibitor” in human plasma by validating the developed method in accordance to US-FDA guidelines. Methodology Envisaged: BTZ D3 was used as...
Open access
Research Article10.9734/bjpr/2016/30565
Carbohydrate antigen 19–9 (CA 19–9) is a tumor–associated antigen, which is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes. The aim of this study was to evaluate serum CA19–9 levels in patients with typ...
Open access
Research Article10.9734/bjpr/2016/30808