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All published articles 195

Neuroinflammation and Cognitive Decline: Molecular Crosstalk between Immune and Neural Pathways in Neurodegeneration

Toyin Tolulope Lawal, Naomi Ama Kedador, Funmilade Taiwo Adetola, Reuben Adelala Aragbaye, Olachi Emenyonu, Chinyere Abigail Onyekwum & Fausta Chinyere Diala-Obi · Asian Journal of Research and Reports in Neurology · 2026

Neurodegenerative disorders are associated with progressive neuronal dysfunction, synaptic loss, and cognitive decline. Increasing evidence indicates that chronic neuroinflammation contributes to these processes through sustained interactions between immune and neural pathways. T...

Open access Research Article 10.9734/ajorrin/2026/v9i1181

Neurobehavioral and Biochemical Effects of Caffeine and Vernonia amygdalina Leaf Extract in Healthy Male Wistar Rats

B. C. Robinson, B. C. Chinko, V. O. Hart & S. O. Ojeka · Asian Journal of Research and Reports in Neurology · 2026

Caffeine is a non-selective antagonist of adenosine A1 and A2A receptors, whereas Vernonia amygdalina contains phytochemicals with reported antioxidant and anti-inflammatory properties. Although both agents have been examined separately, information on their comparative and combi...

Open access Research Article 10.9734/ajorrin/2026/v9i1180

Effects of Concurrent Diazepam and Elaeis guineensis Administration on the Histology of the Prefrontal Cortex in Experimental Animals

O. H. Blackie, O. C. Ogbe, W. O. Ajanwachukwu, F. F. Blackie, S. B. Olukayode, R. J. Enoghase & W. O. Ohiwerei · Asian Journal of Research and Reports in Neurology · 2026

The prefrontal cortex is a major region of the brain involved in cognition, emotional regulation, decision-making, and behavioral coordination, and is highly susceptible to neurochemical alterations induced by central nervous system depressants. This study investigated the histom...

Open access Research Article 10.9734/ajorrin/2026/v9i1179

Neuroprotective Effect of Low-Dose of Vitamin A on the Prefrontal Cortex of Methamphetamine Induced Adult Male Wistar Rats

Ezejindu Damian NNABUIHE, Alozie Osinachi Prince, Onyebu Chidinma Emilia, Udodi Sopuluchukwu Princewill, Enemuo IJEOMA, Okeke Somadina Nnamdi, K. Ogbuokiri Doris, Okeke Henry Kachikwuru, Ekoh Augustine Alobu, Nwaefulu Kester Eluemunor, Sobanke A. Omolara, Chidinma Ifeyinwa Mmaju, Okafor Anulika Jacinta, Chuka-Onwuokwu Ngozi Cynthia, Ejiogu Ikedichukwu Chibueze, Nwoko Sebastine Okechukwu, Wuraola Serah Nnaemeka, Ebi Victory Chinecherem, Agu Augustine Uchenna, Ugwu Augustus Uchenna & Nwodo Ndubuisi Francis · Asian Journal of Research and Reports in Neurology · 2026

Methamphetamine is a potent psychostimulant known to induce oxidative stress and neurodegeneration, particularly in the prefrontal cortex, which is responsible for executive and cognitive functions. Vitamin A, an essential antioxidant, may offer neuroprotection by modulating oxid...

Open access Research Article 10.9734/ajorrin/2026/v9i1178

Prevalence and Risk Factors of Suicidal Ideation among Pregnant Adolescents in Low- and Middle-Income Countries: A Scoping Epidemiological Review

Tanisha Ghosh, Swagata Sarkar, Ananya Ghosh & Puspen Ghosh · Asian Journal of Research and Reports in Neurology · 2026

Background: Adolescent pregnancy is a major public health concern in low- and middle-income countries (LMICs), with poor maternal and mental health outcomes driven by socioeconomic vulnerability, gender inequality, and limited access to care. Suicidal ideation among pregnant adol...

Open access Research Article 10.9734/ajorrin/2026/v9i1177

Neurochemistry and Histological Studies of the Prefrontal Cortex of Adult Wistar Rats after the Administration of Ethanolic Leave Extract of Psidium guajava Linn (Myrtaceae)

Kingsley Akaninyene Okon & Nsikan-Abasi Bassey Udoh · Asian Journal of Research and Reports in Neurology · 2026

Background: Guava (Psidium Guajava), a large dicotyledonous plant easily identified by its copper-coloured thin smooth bark with greenish colouration underneath is an example of such plant with reportedly wide range of medicinal values. Aims: The study aims to investigate the neu...

Open access Research Article 10.9734/ajorrin/2026/v9i1176

The Airpod Sign in Bilateral Medial Medullary Infarction after Rapid Neurological Deterioration: A Case Report

Samar Eshetawe, Mohammad F. Salawati, Saqer Bulayhid H. Albulayhid, Abdullah Ibrahim Bin Eid, Saleh Saeed A. AlQahtani & Fahad Hammad F. Alrayes · Asian Journal of Research and Reports in Neurology · 2026

Bilateral medial medullary infarction is a rare and potentially devastating posterior circulation stroke that may be missed in its earliest stages because initial symptoms can be nonspecific and computed tomography‑based imaging may be unrevealing. We report the case of a 65‑year...

Open access Research Article 10.9734/ajorrin/2026/v9i1175

A Scoping Review of Laser-based Visual Cueing Strategies for the Management of Freezing of Gait in Parkinson’s Disease

K. R. Athul Krishna, Riyas Basheer K B, Ismail Hazim, P. G. Krishnendu & Subhashchandra Rai · Asian Journal of Research and Reports in Neurology · 2026

Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic degeneration and Lewy body pathology, leading to impaired basal ganglia function and motor symptoms such as bradykinesia, rigidity, tremor, and gait disturbances. Freezi...

Open access Research Article 10.9734/ajorrin/2026/v9i1174

Knowledge of Bipolar Disorder among Undergraduates of Selected Departments in Abia State University, Uturu, Nigeria

Uka-Kalu, Ezinne Chioma, Uwaeme, ThankGod Chimeremeze & Chukwuka, Goodnews Chinaza · Asian Journal of Research and Reports in Neurology · 2026

Background: Bipolar disorder is a chronic mental health condition that typically emerges during late adolescence and early adulthood, coinciding with the university years. Poor knowledge of the disorder persists among university students, contributing to delayed diagnosis, stigma...

Open access Research Article 10.9734/ajorrin/2026/v9i1173

Histological and Histochemical Studies on the Hippocampus Induced with Lead Acetate Following Oral Administration of Ethanolic Cowpea Extract on Adult Male Wistar Rats

Elemuo, Stanley Chukwuebuka & Anyiam, Kennedy Ekenedirichukwu · Asian Journal of Research and Reports in Neurology · 2026

Aim: This study aimed to ascertain the neuroprotective effects of Vigna unguiculata on adult male wistar rats following lead induced neurotoxicity. Study Design: 25 rats were randomly assigned into five groups (n=5): Group A (control), Group B (15 mg/kg lead acetate), Group C (15...

Open access Research Article 10.9734/ajorrin/2026/v9i1168

Congenital Facial Paralysis Associated with Grade III Microtia in a 13-Year-Old Male: A Case Report

Mohammed Mustafa Khan, Harun Siddiqui, Geetika Srivastava, Mohammed Qaim Rizvi & Rishabh Dubey · Asian Journal of Research and Reports in Neurology · 2026

As a background, microtia and congenital facial paralysis are both extremely rare disorders that provide formidable clinical obstacles. They require extensive interdisciplinary care since their simultaneous presence is so rare. We present a case of a male patient, 13 years old, w...

Open access Research Article 10.9734/ajorrin/2026/v9i1172

Clinical-Demographic Profile and Outcome of Mechanical Ventilator Liberation in Neurologically Critical Patients of Southeastern Mexico

María del Rosario López Morales, Jimmy José Góngora Mukul, Román Alejandro Maldonado Sansores, Jesica Margot Toraya Vargas, Isabel Alejandra Gómez Rojas, Pedro Iván Loeza Rea, Pedro Ricardo Díaz Cruz & Ernesto Abrahan Sedano Monroy · Asian Journal of Research and Reports in Neurology · 2026

Background: Invasive Mechanical Ventilation (IMV) is essential in most neurologically critical patients. Therefore, it is important to provide conditions that protect the airway and prevent secondary brain damage. However, physiological instability increases the risk of failure i...

Open access Research Article 10.9734/ajorrin/2026/v9i1171

Patterns of BDNF Dysregulation Following Cannabinoid Supplementation in Male Wistar Rats

Elizabeth Eepho Krukru, Bruno Chukwuemeka Chinko & Victor Datonye Dapper · Asian Journal of Research and Reports in Neurology · 2026

Background: Brain-derived neurotrophic factor (BDNF) is a critical biomarker implicated in the pathophysiology of various neurological and psychiatric disorders. This study investigated the dose- and time-dependent effects of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CB...

Open access Research Article 10.9734/ajorrin/2026/v9i1170

Molecular Evaluation of Oligodendrogliomas Using Next Generation Sequencing: The GCRI Experience

Dhruva Trivedi, Mittal Mistry, Pina Trivedi, Richa Soni & Trupti Trivedi · Asian Journal of Research and Reports in Neurology · 2026

Introduction: Oligodendroglioma is a rare, slow-growing glioma originating from oligodendrocytic cells and primarily affects adults. According to the 5th edition of the World Health Organization Classification of Tumors of the Central Nervous System, a definitive diagnosis requir...

Open access Research Article 10.9734/ajorrin/2026/v9i1169

A Field Survey of Available Anti-Epileptic Drugs (AEDs) in Lagos - The Commercial Hub of Nigeria: Success and Challenges

Adekunle Fatai MUSTAPHA, Michael Bimbo FAWALE, Chiyememma Claire WORLU, Toluwalope David OYETUNDE, Aaron ThankGod UKA & Oluwadamilola Opeyemi ADENEKAN-OKONJI · Asian Journal of Research and Reports in Neurology · 2026

Background: Access to anti-epileptic drugs (AEDs) remains a major challenge in low- and middle-income countries, despite significant advancements in epilepsy therapy. Availability of both older and newer AEDs varies widely across regions, and limited access contributes to poor se...

Open access Research Article 10.9734/ajorrin/2026/v9i1166