Isoniazid is an important first-line antituberculosis drug; however, its administration may induce oxidative stress and hepatic biochemical disturbances. This study evaluated the effects of nutraceutical antioxidants and functional foods on isoniazid-induced oxidative stress and...
Open access
Research Article10.9734/ajrrhe/2026/v8i167
Background: Diabetes mellitus is frequently accompanied by hepatic dysfunction, dyslipidaemia, and impaired protein metabolism, which contribute substantially to disease progression and cardiovascular risk. Although Moringa oleifera and Tamarindus indica possess documented antidi...
Open access
Research Article10.9734/ajrrhe/2026/v8i166
Background: Budd–Chiari syndrome (BCS) results from hepatic venous outflow obstruction and is rarely associated with external compression by hepatic hydatid cysts. Small cysts at the hepatic dome may cause early venous indentation before thrombosis or classical radiological featu...
Open access
Research Article10.9734/ajrrhe/2026/v8i165
Doxorubicin is an effective anticancer drug, but its clinical use may be limited by tissue toxicity, including liver injury. This study evaluated the acute toxicity profile and possible hepatoprotective effect of ethanol seed extract of Persea americana in doxorubicin-induced mal...
Open access
Research Article10.9734/ajrrhe/2026/v8i164
Background: Primary biliary cholangitis is a chronic autoimmune cholestatic liver disease that predominantly affects women; however, male patients may present with delayed recognition and more advanced disease. Data on primary biliary cholangitis in men remain limited in North Af...
Open access
Research Article10.9734/ajrrhe/2026/v8i163
Background: Seronegative primary biliary cholangitis (snPBC) is an uncommon variant of PBC in which characteristic antimitochondrial antibodies are absent despite clinical, biochemical, and histological features consistent with the disease. The lack of serological markers may del...
Open access
Research Article10.9734/ajrrhe/2026/v8i162
Background: Malignant biliopancreatic strictures are a major cause of obstructive jaundice and are frequently associated with advanced pancreatic and biliary malignancies. Endoscopic retrograde cholangiopancreatography (ERCP) with biliary drainage remains the preferred palliative...
Open access
Research Article10.9734/ajrrhe/2026/v8i161
Hepatitis A virus (HAV) infection is a common cause of acute viral hepatitis in children and usually follows a benign, self-limited course (Schiff, 1992, Wang et al., 2015, Tong et al., 1995). However, atypical manifestations are increasingly recognized, and prolonged cholestatic...
Open access
Research Article10.9734/ajrrhe/2026/v8i160
Background: Obstructive jaundice is a common hepatobiliary disorder characterized by impaired bile flow and cholestasis, leading to significant morbidity if not promptly treated. Gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) are key cholestatic liver enzymes wid...
Open access
Research Article10.9734/ajrrhe/2026/v8i159
Ransford Oduro Kumi, Belinda Oti, Andrews Kumi, Erica Morvey Mawulorm, Gloria Donkor, Ampomah Abena Asante, Emmanuel Ayitey, Rita Oforiwaa Aygeman Ntim, Sefakor Adzo Agbenyegah & Isaac Kporha·Asian Journal of Research and Reports in Hepatology·2025
Background: Neonatal jaundice is a major contributor to neonatal morbidity and mortality in sub-Saharan Africa. Understanding its determinants is vital for improving neonatal outcomes. This study assessed the prevalence and determinants of this public health challenge in two hosp...
Open access
Research Article10.9734/ajrrhe/2025/v7i158
Ahmed Lutful Moben, Rokshana Begum, Sheikh Mohammad Noor E Alam, Md. Abdur Rahim, Bishnu Pada Dey, Musarrat Mahtab, Sheikh Mohammad Fazle Akbar & Mamun Al Mahtab·Asian Journal of Research and Reports in Hepatology·2025
Idiopathic Noncirrhotic Portal Hypertension (INCPH) is a rare disease entity which is characterized by intrahepatic portal hypertension in the absence of cirrhosis and other liver diseases and splanchnic venous thrombosis. Etiology of INCPH remains unknown and immunological disor...
Open access
Research Article10.9734/ajrrhe/2025/v7i157
Introduction: Jaundice is a yellowing of the skin and mucous membranes caused by hyperbilirubinemia. The aim of this study was to describe the epidemiological and diagnostic profile of jaundice in The Hepatology and Gastroenterology Department at Gabriel Touré University Hospital...
Open access
Research Article10.9734/ajrrhe/2025/v7i156
AZONWAKIN RODRIGUE AKOTEGNON., ASSIRIUS KOTOMALE, Clémentine Michodjehoun, Steven Chokki, Fatoumata Bah, Euloge Oscar Manhognon Faton, ABDOURAMANE DIENG & Lamine Baba-Moussa·Asian Journal of Research and Reports in Hepatology·2025
Gastric ulcer is a multifactorial disorder characterized by disruption of the gastric mucosa, often induced by ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), oxidative stress, or Helicobacter pylori infection. This study investigated the gastroprotective activity of the...
Open access
Research Article10.9734/ajrrhe/2025/v7i155
Background: Platelet count and platelet indices are cheap, accurate and available methods to estimate fibrosis in Nonalcoholic fatty liver disease (NAFLD) patients. Aim: This work aims to study platelet count and platelet indices as markers of fibrosis in NAFLD patients. Methods...
Open access
Research Article10.9734/ajrrhe/2025/v7i154
Aims: This study evaluates the hepatoprotective and antioxidant potential of the ethanolic extract of in high-fat-streptozotocin-induced diabetic Wistar rats. Pleurotus tuber-regium is an oyster mushroom rich in essential nutrients and possesses anti-inflammatory, hypoglycemic, a...
Open access
Research Article10.9734/ajrrhe/2025/v7i153