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All published articles 195

Endotyping Cellular and Humoral Immunoreactivity against Pollen and Citrus Fruits in Patients with Non–IgE-mediated Rhinoconjunctivitis

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Nicole Sartoreto da Rocha, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2025

Background: Allergies to citrus fruits are often associated with pollinosis due to cross-reactivity among pollen and food allergens (fruit-pollen syndrome) displayed in patients with several conditions, such as allergic rhinoconjunctivitis. Aim: To evaluate the potential of the T...

Open access Research Article 10.9734/aji/2025/v8i1156

Preclinical Immunogenicity of Capsule and Outermembrane Proteins of a Local Neurotropic Isolate of Hemophilus Infleunzae B in a Lapin Model

Ibrahim M S SHNAWA, Azhar O AL-Thahab & Kasim N A.Thewaini · Asian Journal of Immunology · 2025

The preclinical immunogenicity of capsule C and outer membrane protein OMP of human neurotropic isolate of Hemophilus influenzae b HIB in a lapin model is being reported. Hemophilus influenzae b is gram negative, short rods, encapsulated bacterium, microaerophilic, fastidious, ne...

Open access Research Article 10.9734/aji/2025/v8i1155

Assessing Cellular and Humoral Immunoreactivity to Lanolin: A Retrospective Cohort Study in Atopic and Contact Dermatitis Patients

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2024

Background: Several publications report lanolin as responsible for hypersensitivity reactions in patients with atopic dermatitis and/or contact dermatitis, as diagnosed by in vivo provocation tests. There is no standardized lab exam that can endotype the mechanisms responsible fo...

Open access Research Article 10.9734/aji/2024/v7i1154

A Review on Vadadustat: Hope in Treatment of Anemia Patients Having Chronic Kidney Disease

Nikita Gupta, Mohd Naveed Khan, Varda Farooqui, Guntoju Poojitha & Thipparam Kavya · Asian Journal of Immunology · 2024

Vadadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, may offer an oral alternative to injectable erythropoiesis-stimulating agents (ESAs) to treat anemia in patients undergoing peritoneal dialysis. Current standard of care for anemia linked to chronic kidney disea...

Open access Research Article 10.9734/aji/2024/v7i1153

Effect of Alstonia boonei and Morinda lucida on Renal Histology of Wistar Rats Infected with Trypanosoma brucei brucei

Onaolapo, Y.A., Mazadu, R.M., Baraya, K.Y., Fasuyi, F.H., Irhue, A.E., Ahmed, B., Hassan, A., Shehu, A.A., Bala, S.B., Kasim, S.N. & Kugama, M.A. · Asian Journal of Immunology · 2024

Animal African trypanosomiasis is a protozoan disease caused by trypanosomes and transmitted through the bite of an infected tsetse fly. The disease has an adverse effect to the economy of the affected areas and drugs used for the treatment of the disease are faced with several c...

Open access Research Article 10.9734/aji/2024/v7i1152

Immune Characterisation of Human Local Pneumotropic Isolates of Streptococcus pneumoniae Serotype 1 and 6 as Local Vaccine Strains

Shnawa I M S & AL-Janabi AAJ · Asian Journal of Immunology · 2024

pneumoniae is one of the principle human pneumopathogen. Such pathogenicity features in man can be delineated by severity, capsule nature and yield of pure growth onto primary plate cultures. While in laboratory animal models, it accounts for; the nature of capsule serotype, shor...

Open access Research Article 10.9734/aji/2024/v7i1151

Cellular and Humoral Immunoreactivity against Hen’s Egg White: Relevance in Allergic Patients

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2024

Background: Hypersensitivity to chicken eggs is the second most common food allergy, presenting IgE-mediated and non-IgE-mediated hypersensitivity mechanisms. While IgE-mediated hypersensitivity is easily detected, non-IgE-mediated endotypes present challenging obstacles to diagn...

Open access Research Article 10.9734/aji/2024/v7i1150

Gonadal Histo-morphology and Enhanced Fertility Potential of Curcuma longa in Male STZ-induced Diabetic Rats

Mfon I Akpaso, Elton N Takim, Michael E Oku, Anani, S.E., Lydia B Edim & Gabriel U Udo-Affah · Asian Journal of Immunology · 2024

Diabetes mellitus is a disorder in which the body fails to produce enough or respond normally to insulin, leading to abnormally high blood sugar levels. The study was aimed at investigating the effects of ethanolic extract of Curcuma longa (Tumeric) on fertility profile and gonad...

Open access Research Article 10.9734/aji/2024/v7i1149

Optimizing Cancer Immunotherapy through Combination Therapies: Advances in Chemoimmunotherapy, Lymphodepletion, and Precision Medicine

Shen Li & Biaoru Li · Asian Journal of Immunology · 2024

Chemoimmunotherapy was a challenge issue in an early clinical study. Cytotoxic chemotherapy was immunosuppressive while, in the clinic, chemoimmunotherapy demonstrated supporting immunotherapy. To increase ACT (adoptive cell transfer) immunotherapy and decrease the effects of che...

Open access Research Article 10.9734/aji/2024/v7i1148

Long-lasting Response of Human Circulating T-follicular Helper Cells (cTfh) To Post SARS-CoV-2 mRNA Immunization

Sandhya Shukla, Arvind Kumar Shukla, Navin Ray, Adarsha Mahendra Upadhyay, Giovanna Mirone & Raj Kumar Mongre · Asian Journal of Immunology · 2024

The ongoing COVID-19 pandemic underscores the urgent need for effective vaccination strategies to mitigate disease burden. The development of neutralizing antibodies is a critical indicator of host defence mechanisms against life-threatening infectious diseases, such as those cau...

Open access Research Article 10.9734/aji/2024/v7i1147

Endotyping Cellular and Humoral Immunoreactivity against Tartrazine in Allergic Patients: A Retrospective Study

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2024

Background: Several publications report that tartrazine is responsible for IgE-mediated and non–IgE-mediated hypersensitivity reactions. There is no standardized lab exam to endotype non–IgE-mediated immunoreactivity against tartrazine besides in vivo provocation tests. Aim: To e...

Open access Research Article 10.9734/aji/2024/v7i1146

Seroprevalence of Hepatitis B and Hepatitis C Viral Infections in Port Harcourt, Nigeria

Chidi L.C. Ndukwu & Jane Ugochi Chinedu-Madu · Asian Journal of Immunology · 2024

Introduction: Viral hepatitis which includes five the main strains of hepatotropic viruses, hepatitis A (HAV), hepatitis B (HBV), (HBA), hepatitis C (HCV), hepatitis D(HDV), and hepatitis E (HEV), are leading causes of morbidity and mortality globally. Much public health attentio...

Open access Research Article 10.9734/aji/2024/v7i1145

Endotyping Cellular and Humoral Immunoreactivity against Allium Spices and Sulfites Preservatives in Allergic Patients: A Retrospective Study

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima · Asian Journal of Immunology · 2024

Background: Spices from the Allium genus season food worldwide, and their widespread use may produce allergic reactions by contact or ingestion. However, the Non–IgE-mediated immunoreactivity against these allergens has not yet been adequately investigated. Aim: To evaluate the p...

Open access Research Article 10.9734/aji/2024/v7i1143

Immunogenicity of Bacterial Protoplasmic Sonicate Proteins

Shnawa IMS, Algerbori HSH & Thewaini QNO · Asian Journal of Immunology · 2024

Bacterial Protoplasmic Sonicate Proteins BPSP were recovered from skin burn Pseudomonas aeruginosa and Klebsiella oxytoca infections. These proteins   were considerd as immunogens in rabbits. Mucosal and systemic, humoral and cellular immune immune responses were matched. The P....

Open access Research Article 10.9734/aji/2024/v7i1141