Background: Activation of the coagulation cascade frequently occurs in cancer by a number of mechanisms, including the generation of tumor necrosis factor, tumor pro-coagulant and tissue factor. Aim: The purpose of this study was to investigate the plasma level of PC, FIB, DD and...
Amah Akuma Kalu, Eberechukwu Lolly Mbanaso, Onwuka Kelechi Collins, Ubani Clement Dimgba & Chris Akunne Wariso·Asian Hematology Research Journal·2023
The kidney is one of the most important organs of the body saddled with critical physiological functions one of which is the elimination of metabolic waste products from the blood. Drugs, chemicals, pesticides and pollutants can pose threat to the kidney and often times, collaps...
ITP is a chronic illness with frequent mucosal bleeding. Though the first line treatment is corticosteroids, relapse is frequent which necessitates splenectomy. Response to splenectomy is usually good initially; however, over the years relapses are frequent. Drugs then used are...
Houda Kouame, Hanaa Bencharef, Mohammed Benamor-Seghir, Karima Arioua-Mikou & Bouchra Oukkache·Asian Hematology Research Journal·2023
Background: In a medical laboratory, monocytosis is very common, often reactive, but may be related to a hematological malignancy, particularly Chronic myelomonocytic leukemia (CMML). CMML is considered a diagnosis of elimination given the frequency of reactive monocytosis. This...
Background: Warfarin prolongs coagulation by inhibiting the synthesis of biologically active forms of coagulation factors and regulatory factors, which are dependent on vitamin K. The Prothrombin Time (PT) and International Normalized Ratio (INR) are routinely used to monitor war...
Chibuike Obiandu, Joy O. A. Laz-Okenwa, Bright I. Owhorji, Eunice I. Oriji, Abiye Tamuno-Opubo & Henrietta O. Asuzu-Samuel·Asian Hematology Research Journal·2023
Rhizophora mangle is a mangrove plant found mainly in coastal lands of tropical and subtropical regions. It is a medicinal plant applied in folklore remedies in the treatment of fever, toothache, sore throat, constipation, etc.. This study investigated the effects of the leaves o...
Chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) are amongst the commonest forms of leukemia seen in adult population which have different lineage of origin. They have rarely been reported to be diagnosed simultaneously in one patient. Here we report a rare c...
. Sandeep, Ashish Upadhyay, Harsha P. Panchal, Apurva Patel, Sonia K. Parikh, Kajal Shah, Khushboo Jain & Abhijeet Kokate·Asian Hematology Research Journal·2023
Methotrexate associated lymphoproliferative disorders (MTX-LPD) are lymphomas that develop after administration of methotrexate (MTX). Here, we report a case of MTX-LPD in a 58-year-old female with rheumatoid arthritis (RA) who was on methotrexate for 10 years. She presented with...
Background: Oxidative stress and free-radicals could be responsible the pathogenesis and prognosis of primer immune thrombocytopenia (ITP). Paraoxonase-1 (PON-1) is an antioxidative feature. In this study, it had investigated that the role of PON-1 Leu (L)/Met (M) 55 gene polymor...
Diabetes mellitus a chronic, progressive, metabolic disorder characterised by hyperglycemia initially because of tissue insulin resistance and gradually progressing to complete loss of secretory activity of the beta cells of the pancreas, most frequently caused by impaired insuli...
Introduction: Bone marrow aspiration and biopsy forms the foundation of diagnostic hematopathology. These outpatient procedures were performed under local anaesthesia yielding accurate and timely diagnosis. Aim: To evaluate the utility of bone marrow biopsy in the diagnosis and f...
Mitsan Olley, Sule Zekeri, Josiah Joel Sunday, Aiyanyor David Osayomwanbo & Awa Favour Chinatu·Asian Hematology Research Journal·2023
Blood transfusion is a critical part of patient’s intensive care and is life saving for patients with severe anemia or hemorrhage. The goal of blood banking is to provide adequate and safe blood to recipients at no risk to donors. These donors may have had a variety of exposures...
Salman Taha Ahmed Elmukashfi, Walaa Maryoud Aljack, Mihad Magboul Ahmed, Abdelrahman Mohamed Sidahmed Mohamed & Ahmed Yasin Hassan·Asian Hematology Research Journal·2023
Background: A wide array of disturbances in electrolyte equilibrium is commonly seen in patients with acute leukemia (AL). These abnormalities present a potential hazard in these patients, as that of enhancing the cardio-toxic effects of certain chemotherapeutic regimens. Materia...
Introduction: SARS-CoV-2 infection can cause manifestations in multiple systems in the body. Haematological system can also be affected by both SARS-CoV-2 infection and critical illness. There have been studies that show thrombocytopaenia is connected with SARS-CoV-2 infection. ...
Abhay A. Bhave, Sarang Waghmare, Nitin Chavan, Kashvi Mehta, Fatema Rangwalla & Shrinath Kshirsagar·Asian Hematology Research Journal·2023
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a fatal disorder, characterized by a cytokine storm due to cytotoxic T cell activation, the causes of which are various. Its detection is first on clinical awareness and proved by several tests. However, there is not one s...