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Modulatory Effect of Aqueous Ginger (Zingiber officinale) Extract on Gentamicin Sulfate Induced Oxidative Stress and Nephrotoxicity in Female Albino Rats

Henry Wealth Oyarieme, Akinniyi Adediran Osuntoki, Holiness S.A. Olasore, Ogheneovo Obros, Jeromi Otiti & Zakariyah Abdullahi Abiodun · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Acute renal failure is a common complication of gentamicin, an aminoglycoside antibiotic widely used against gram-negative infections, often mediated by oxidative stress. This study investigates the potential protective effects of aqueous ginger extract against gentamicin-induced...

Open access Research Article 10.9734/ajbgmb/2024/v16i9404

Improving Food Safety in Africa Using Cutting-Edge Biotechnology & Molecular Biology Approaches

Yusuf Alhassan, Abdullahi Olanrewaju Ajadi, Oni Gbotemy Jerry, Ahmed Wopa Wurie & Temitope Esther Olajide · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Ensuring food safety in Africa is a critical challenge that requires innovative approaches. Food safety is a pressing concern in Africa, where the prevalence of foodborne diseases and contamination poses significant health and economic challenges. This review explores the potenti...

Open access Research Article 10.9734/ajbgmb/2024/v16i9403

The Tale of Warrior Gene: The MAOA-upstream Variable Number Tandem Repeat (MAOA-uVNTR) Polymorphism and Its Role in Shaping Aggressive and Violent Behaviour

Minasha R Abeykoon, Chanika D Jayasinghe, Ruwan J Illeperuma & Thelma Abeysinghe · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The Monoamine Oxidase A (MAOA) gene has acquired significant attention across the field of behavioral genetics over time due to its association with different adverse impacts it has had on altering human behavior. Research suggests that specific genetic variations of the MAOA gen...

Open access Research Article 10.9734/ajbgmb/2024/v16i9402

Peroxidase Activity in Extracts of Watermelon Pulp: Effects of Ethylenediaminetetraacetic Acid and Some Cations

Iniaghe, O.M & Ohilebo A.A · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aim: The aim of this study was to evaluate the effects of EDTA and some chloride salts of Ca, Cr, Fe and Mg on the initial velocity (Vo) of crude peroxidase from the pulp of watermelon. Study Design: The study design is In vitro enzyme assay. Place and Duration of Study: This stu...

Open access Research Article 10.9734/ajbgmb/2024/v16i8401

Effects of Eleophorbia drupifera Leaves Extract on Some Biochemical and Haematological Parameters of Albino Rats

Nyah, Nkereuwem U., Obosi, Ekemini J., Ekong, Udeme, J., Ukpong, Etiowo G & Chukwuemeka, Iheanyichukwu E · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Water and ethanol-water extracts of Eleophorbia drupifera leaves were administered orally in graded doses of 0.5ml (147.06mg/kg body weight), 1.0ml (303.3 mg/kg body weight) water extract and 0.5ml (157.66 mg/kg body weight), 1.0ml (301.72 mg/kg body weight) ethanol-water extract...

Open access Research Article 10.9734/ajbgmb/2024/v16i8400

Genetic Differentiation of Indian Zebu Cattle (Bos tauraus) Breeds Using Random Oligonucleotide Primers (RAPD-PCR) in Amravati Region, Maharashtra, India

Nilima J. Tayde, Hemlata P. Nandurkar & Nandakishor E. Warghat · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

In India, insufficient characterization skills and extensive crossbreeding of cattle have led to the loss of several breeds. The purpose of this work is to find polymorphic primers for identifying Zebu cattle breeds. Random crossbreeding has resulted in genetic losses among the G...

Open access Research Article 10.9734/ajbgmb/2024/v16i8399

Antimicrobial Resistance and Phenotypic Detection of Extended Spectrum Beta-Lactamase in Escherichia coli from Children with Cases of Diarrhea in Nasarawa-South, Nasarawa State, Nigeria

Zakou AT, Ngwai YB, Nkene IH, Ishaleku D, Abimiku RH & Ekeleme IK · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Aims: This study investigates the antimicrobial resistance and phenotypic detection of extended-spectrum beta-lactamase in Escherichia coli from children with cases of diarrhea in Nasarawa-south, Nasarawa State, Nigeria. Place and Duration of Study: Nasarawa South, Nigeria, in 20...

Open access Research Article 10.9734/ajbgmb/2024/v16i8398

Emerging Role of Probiotics in Advancement of Combating Physical Abnormalities and Diseases: A Systematic Perspective Analysis

Mst. Tania Khatun, Forkanul Hoque, Naeema Salatia Hoque, Md. Sakhawat Hossain, Md. Ashraful Alam, Sabrina Afrin, Tanjina Nasrin Eva & Rahima Tanbin Tama · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Probiotics are live microorganisms, primarily bacteria that give the host health benefits when given in sufficient amounts. It works in various defensive mechanisms, including releasing antimicrobial compounds, competitive adhesion to the mucosa and epithelium, fortifying the gut...

Open access Research Article 10.9734/ajbgmb/2024/v16i8397

Spectral Characterization of Canarium ovatum Engl. (Pili) Pulp Extract from Allen, Northern Samar, Philippines

Harley Nico L. Jazmin, Flyndon Mark S. Dagalea & Karina Milagros Cui-Lim · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Canarium ovatum (Pili) Pulp was widely cultivated in the town of Allen, Northern Samar, Philippines. In Allen, Northern Samar produces 60 to 100 kilograms per year every tree. The pili can used in various aspects like oil and soap production, fuel, sweet candies and bread stuffin...

Open access Research Article 10.9734/ajbgmb/2024/v16i7396

Effect of Garcinia Kola in Ivermectin-Induced Toxicity in the Hematology of Treated Rats (Rattus Novergicus)

Benjamin Nnamdi Okolonkwo, Godspower Ikechi Achi, Erasmus Martha A, Suama Promise, Patrick Williams, Osuosa Atoukaritou & Esther Okagbe Ogbugo · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Garcinia kola (GK) is prized in African herbal medicine for its diverse uses, including social, economic, and medicinal purposes. This study examined the dose-dependent toxicity of ivermectin and the protective effects of Garcinia kola extract on the hematological parameters of W...

Open access Research Article 10.9734/ajbgmb/2024/v16i7395

Evaluation of Genotoxicity by Comet Assay in Tissues of Clarias gariepinus Exposed to Cassava Effluent

Daniel I. Olorunfemi, Osuvwe C. Orororo, N. E., Iloduba, Ejovi Osioma, Enyohwo D. Kpomah & Ogheneovo L. Osio · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Untreated wastewater discharge into waterbodies poses a number of risks, including the potential for aquatic organisms' DNA to be damaged. Using the comet assay, this study assessed the genotoxic impact of cassava wastewater on the gonads, liver, and gills of post-juvenile Claria...

Open access Research Article 10.9734/ajbgmb/2024/v16i7394

GC-MS Charaterization of Phytochemicals and Anti Microbial Properties of Chromolaena odorata Leaf Harvested from South Eastern Nigeria

Emeziem D.M & Iwu I C · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The analysis of the leaf extract of Chromolaena odorata was carried out to characterize its components, GC-MS analysis was carried out in our laboratory. The spectrum obtained showed 15 peaks which translates to 15 compounds, with their molecular weight, formula and structures. I...

Open access Research Article 10.9734/ajbgmb/2024/v16i7393

Identification of Novel Plant-derived Inhibitors of the EGFR Kinase Domain Using vHTS, QSAR and Molecular Docking Approaches

Olawole Yakubu Adeniran · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

The epidermal growth factor receptor (EGFR) protein tyrosine kinase (PTK) is a crucial target in the pursuit of anti-tumor drug discovery. This study investigates 305 phytochemicals from five known anticancer plants (Anacardium occidentale, Annona muricata, Spondias mombin, Ocimu...

Open access Research Article 10.9734/ajbgmb/2024/v16i7392

Comparative Effects of Ripeness on Monoamine Oxidase (MAO) Inhibition and Anti-oxidative Activity of Amelonado and F3 Amazon Cocoa (Theobroma Cacao) Beans In vitro

Shodehinde S.A., Odubanjo Veronica O., Adeniyi S., Adesugba O.D., Egunjobi G.D., Olubode S.O., Akinnusi P.A., Oyeleye S.I., Awojulu V.O, Nwanna E.E & Oboh G. · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Background: The oxidative deamination of amines and neurotransmitters as typified by the action of monoamine oxidase (MAO) is known to be involved in psychological disorders, oxidative stress, and many other adverse pharmacological reactions. A new series of studies have been gea...

Open access Research Article 10.9734/ajbgmb/2024/v16i7391

Nutritional and Anti-oxidative Potentials of Ethanolic Extract of Avocado Pulp (Persea americana Mill) On Caffeine Induced Oxidative Stress on Wistar Rats

Nkwocha, John Nnaemeka & Philip Oseikhuenmhen Ogboye · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

This study evaluated the chemical composition and the effect of ethanolic extract of Persea americana pulp on caffeine induced oxidative stress on male wistar rats. Forty-five (45) mature male rats were used and divided into five (5) groups of nine (9) rats per group. Group two (...

Open access Research Article 10.9734/ajbgmb/2024/v16i7390