Background: Perinatal asphyxia is a leading cause of neonatal morbidity and mortality worldwide. According to the World Health Organization, 3% of all infants in developing countries, that is, approximately 3.6 million experience moderate to severe birth asphyxia. Of these, aroun...
Open access
Research Article10.9734/ajpr/2025/v15i7468
Circular RNA (circRNA) and long non-coding RNA (lncRNA) play a crucial role in gene regulation through microRNA (miRNA) pathways. Initially viewed as a molecular curiosity or a byproduct of RNA splicing processes, circRNAs were largely overlooked. Their biological relevance and d...
Open access
Research Article10.9734/ajpr/2025/v15i7465
Background: Congenital ichthyoses are rare genetic skin disorders characterized by abnormal keratinization, often present at birth and associated with various extracutaneous manifestations. Material and Methods: We conducted a retrospective 30-month study at a Moroccan university...
Open access
Research Article10.9734/ajpr/2025/v15i7464
Castleman disease is a rare lymphoproliferative disorder, particularly in children. Its association with pityriasis lichenoides has not been previously reported. This report presents a 5-year-old girl born to consanguineous parents, who developed recurrent necrotic and bullous sk...
Open access
Research Article10.9734/ajpr/2025/v15i7462
Background: Cutaneous mastocytosis (CM) is a rare pediatric dermatosis characterized by the abnormal proliferation and accumulation of mast cells in the skin. It typically presents in early childhood and is most often confined to the skin, with a generally favorable prognosis. Ma...
Open access
Research Article10.9734/ajpr/2025/v15i7463
Nonaccidental injuries (NAI) and child abuse in adopted children are pressing public health issues, shaped by pre-adoption adversities and post-adoption stressors. This systematic review synthesizes evidence on NAI prevalence, risk factors, screening tools, and perpetrator patter...
Open access
Research Article10.9734/ajpr/2025/v15i7461
Aims: To increase the awareness about retinopathy of prematurity (ROP) blindness in unscreened preterm infants in Abuja”. Presentation of Cases: Five (5) children who had become blind from ROP and referred to our facility were seen. Three of them were males. The mean gestational...
Open access
Research Article10.9734/ajpr/2025/v15i7460
S Siva Sankar, R Arun Kumar, M Alexander, S Vijayarangan, R Balamurugan, V Arun Gandhi, K Pavithra, M Kumaravel & R Ezhil Arasan·Asian Journal of Pediatric Research·2025
Background: Infantile colic, characterized by repeated episodes of intense crying, is a distressing condition for parents, and its unknown etiology complicates the treatment. This study investigates the efficacy and safety of a fixed-dose combination of probiotics, digestive enzy...
Open access
Research Article10.9734/ajpr/2025/v15i6459
Genetic causes of neurodevelopmental disorders are frequent and complex. We Report The case of a 10-month-old infant followed for psychomotor delay, severe hypotonia, spastic movements of the lower limbs, and focal seizure with impaired consciousness. Whole-exome sequencing revea...
Open access
Research Article10.9734/ajpr/2025/v15i6458
Ouissal Essadeq, Narjess Er-rachdy, Meriem Boubekri, Taha Aaboudech, Kaoutar Znati, Laila Benzekri & Nadia Ismaili·Asian Journal of Pediatric Research·2025
Background: Lichenoid mycosis fungoides is an exceptionally rare entity in children, often posing significant diagnostic challenges due to its atypical presentation and resemblance to benign dermatoses. Case Report: We report a pediatric case of lichenoid mycosis fungoides presen...
Open access
Research Article10.9734/ajpr/2025/v15i6457
Noura Agarrab, Azzeddine Laaraje, Radi Abdelilah, Soukaina Ait Hmadouch, Amal Hassani & Rachid Abilkassem·Asian Journal of Pediatric Research·2025
Ataxia with oculomotor apraxia type 1 (AOA1) is a rare neurodegenerative disease with autosomal recessive inheritance, caused by mutations in the APTX gene encoding aprataxin, a protein involved in DNA repair. We report the case of a 5-year-old child born to consanguineous parent...
Open access
Research Article10.9734/ajpr/2025/v15i6456
Aims: Hay–Wells syndrome (ankyloblepharon–ectodermal dysplasia–clefting or AEC syndrome) is a rare autosomal dominant disorder caused by TP63 mutations, classically associated with skin, hair, nail, and craniofacial anomalies. Although hair abnormalities are commonly reported, th...
Open access
Research Article10.9734/ajpr/2025/v15i6455
As more and more educational therapists (ETs) have been increasingly encountering terminally-ill or life-limited children in their practice, the need for training and involvement in Pediatric Palliative Care (PPC) has become more pressing. The author of this paper advocates to eq...
Open access
Research Article10.9734/ajpr/2025/v15i6454
Introduction: Due to their increasingly sedentary lifestyles, school-age children are more at risk for hyperlipidaemia, which is defined by increased blood lipid levels. Children who have hyperlipidaemia are far more likely to be obese and have higher BMIs, which increases their...
Open access
Research Article10.9734/ajpr/2025/v15i6452
Background: Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive genodermatosis characterized by poikiloderma, sparse hair, skeletal anomalies, and an increased risk of malignancies, particularly osteosarcoma and skin cancers. RTS is classified into two types: Type I wit...
Open access
Research Article10.9734/ajpr/2025/v15i6451