Flunoxaprofen (FLP) and piroxicam (PIM), acidic non-steroidal anti-inflammatory drugs (NSAIDs), as well as floctafenine (FLN), basic NSAIDs, were coated with anionic and cationic polyacrylic resins adopting the fluidized bed technique. The bioavailability of the uncoated and coat...
Open access
Research Article10.9734/JPRI/2017/38111
Narges Chamkouri, Mona Vafaeizadeh, Ayyub Mojaddami, Seyyed Abed Hosseini, Tahereh Momeni Isfahani, Aida Ghorbani Golkhajeh, Milad Janghorban Lariche & Seyed Mohammad Ali Malaekeh·Journal of Pharmaceutical Research International·2018
In this work, solid phase extraction (SPE) was proposed for simultaneous determination of trace levels of vitamin B6, B9 and B12. High performance liquid chromatography with UV detection (HPLC-UV) was used. The experimental conditions including pH of sample and type and volume of...
Open access
Research Article10.9734/JPRI/2017/34730
Background: Cervical cancer is one of the most common neoplasias in females worldwide. The miRNAs affect cell proliferation and apoptosis in cancers. Low levels of the miR129-2 expression have been linked to human cancer while the SOX4 gene expression has been identified as a nec...
Open access
Research Article10.9734/JPRI/2017/35731
Aims: To screened for phytochemicals and determine the in-vitro efficacy of the plants extracts on Salmonella typhi. Study Design: Phytochemicals and in-vitro efficacy assessment of seven medicinal plants in comparison to the standard antibiotics. Place and Duration of the Study:...
Open access
Research Article10.9734/JPRI/2017/38653
Aims: Acalypha inferno is an ornamental plant which has been shown to be a phytoremediator of zinc. Other species of this genus used traditionally have been proven to possess pharmacologically active constituents. The study sought to evaluate the phytochemical constituents, in vi...
Open access
Research Article10.9734/JPRI/2017/38675
Infertility due to clinical complications or conditions arising due to congenital or acquired absence of a healthy functioning uterus in women leads the couple to opt for surrogacy that involves high risk both for mother and future child. In some societies as in India and in East...
Open access
Research Article10.9734/JPRI/2017/38685
Antibiotics for pediatric use are commonly available as dry powders for reconstitution into oral suspensions. Once reconstituted, these oral suspensions should be refrigerated to preserve their potency and deliver optimal benefit to the patient. However, for reasons ranging from...
Open access
Research Article10.9734/JPRI/2017/38553
Aim: The study evaluated the efficacy and possible mechanism of the stem bark of Zanthoxylum species used by communities and herbalists for wound healing in South Western Uganda. Study Design: Experimental controlled. Place and Duration: Departments of Pharmacy, Pharmacology and...
Open access
Research Article10.9734/JPRI/2017/36766
Aims: Recently the use of antifungal drugs in human medicine has been increased, especially with the advent of AIDS epidemic. The extensive use of antifungal drugs and their resistance against fungal infections have led to the discovery of new antimicrobial compounds. Despite the...
Open access
Research Article10.9734/JPRI/2017/38244
Four simple and accurate spectrophotometric methods were developed for the simultaneous determination of paracetamol, pamabrom and pyrilamine maleate. The first is a zero order spectrophotometric method used for the determination of pyrilamine maleate in presence of paracetamol a...
Open access
Research Article10.9734/JPRI/2017/38353
Aims: Jatropha curcas (J. curcas) is a plant that has numerous medicinal and industrial applications. Evaluation of in vitro and in vivo acute/sub chronic hepato-renal toxicity of crude methanol J. curcas leaf extract on albino rats, in vitro toxicity of the fractions and charact...
Open access
Research Article10.9734/JPRI/2017/38137
Objective: The objective of this research is to investigate the analgesic and antipyretic activity of methanolic extract of Hemigraphis hirta. Methods: Whole dried plant of Hemigraphis hirta was extracted with pure methanol. Analgesic activity was tested by both acetic acid induc...
Open access
Research Article10.9734/JPRI/2017/37077
A novel method for evaluating antitermite activity was standardized whereby filter papers treated with 50% methanolic, 90% methanolic and aqueous extracts of Thevetia peruviana leaves from polluted and non-polluted sites against Odontotermes obesus. In vivo investigation was carr...
Open access
Research Article10.9734/JPRI/2017/37693
Present study was accomplished to prospect the viability of using the montmorillonite (Mon) nanoparticles as an adsorbent to remove the Ampicillin under various experimental conditions. The Physico-chemical characteristics of the studied adsorbent were surveyed. Langmuir, Freundl...
Open access
Research Article10.9734/JPRI/2017/38056
Aim: This work aims at investigating the effect of drying methods on the powder and compaction properties of microcrystalline cellulose (MCC) obtained from the matured fruit husk of Cocos nucifera (CN). Study Design: Experimental design. Place and Duration of Study: University of...
Open access
Research Article10.9734/JPRI/2017/37615