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Is Defibrotide Prophylaxis Effective on Graft Versus Host Disease in Patients with Allogeneic Stem Cell Transplantation?

Irfan Yavasoglu, Atakan Turgutkaya, Hilal Eroğlu Küçükdiler, Gürhan Kadıköylü, Gökhan Sargın & Ali Zahit Bolaman · International Blood Research & Reviews · 2022

Introduction: Sinusoidal obstruction syndrome (SOS) is one of the complications of allogeneic stem cell transplantation (allo-SCT). Defibrotide (DF) is used effectively in SOS prophylaxis and treatment. Graft versus host disease (GVHD) is a significant cause of morbidity and mort...

Open access Research Article 10.9734/ibrr/2022/v13i430184

Current and Emerging Laboratory Techniques for Malaria Diagnosis

Clement Ugochukwu Nyenke, Evelyn Orevaoghene Onosakponome & Roseanne Adah Okafor · International Blood Research & Reviews · 2022

Effective diagnostic methods must continue to be developed due to the effects of malaria on world health. Malaria is an infectious disease spread by mosquitoes that affects both people and other animals. It is the product of Plasmodium parasites, which are transmitted through bit...

Open access Research Article 10.9734/ibrr/2022/v13i430183

Serological Pattern of Hepatitis B Virus Infection and Risk Factors among Infected Individuals in Port Harcourt, Rivers State, Nigeria

Baribefe Banavule Daniel Koate, Teddy Charles Adias, Ebirien-Agana Samuel Bartimaeus & Zacchaeus Awortu Jeremiah · International Blood Research & Reviews · 2022

Hepatitis B virus infection is a serious global public health challenge that affects more than two billion people worldwide. This study aimed to evaluate the serological pattern of HBV infection in HBV infected patients in Port Harcourt, Nigeria. The main aim of this study was to...

Open access Research Article 10.9734/ibrr/2022/v13i430182

Comparism of Microscopy and Molecular Diagnosis of Ehrlichia ruminantium in Cattles in Makurdi Benue Nigeria

Terese Simon Atsuwe, Victor Ugochukwu Obisike & Edidiong John Udo · International Blood Research & Reviews · 2022

Introduction: Makurdi, is the capital city of Benue State, the food basket of the Nigeria, the city challenged with Ehrlichia ruminantium of cattle  that are responsible for severe losses caused either by negative impact of ticks blood loss or blood related infections, damage to...

Open access Research Article 10.9734/ibrr/2022/v13i430181

Haematological and Anthropometric Profile in Gestational Diabetes Mellitus with Non-diabetic Pregnant Women in Port Harcourt, Nigeria

Stella U. Ken-Ezihuo, Paul D. Gorsi, Priya H. Chukwu, Beauty E. Echonwere-Uwikor, Orokwu E. Chukuigwe-Igbere & Ebirien-Agana Samuel, Bartimaeus · International Blood Research & Reviews · 2022

Aim: Haematological and anthropometric profile of pregnant women who had gestational diabetes and non-diabetic pregnant women attending antenatal clinic in a Tertiary Hospital in Rivers State, Nigeria were evaluated, Methods: This was a cross sectional study involving 70 pregnant...

Open access Research Article 10.9734/ibrr/2022/v13i330179

A Case of Overlapping Autoimmune Sclerosing Cholangitis and Autoimmune Hemolytic Anemia

Mouayad Al Shtawi, Ashraf ALakkad, Naser Al Zein, Amer Masaud Azaz & Imad Shubbar · International Blood Research & Reviews · 2022

This case study revolves around a 14-year old female patient, who was otherwise healthy and normal, but brought to the hospital for her condition. The patient presented with complaints of fever, sore throat, severe abdominal pain, and generalized body aches for the last two days....

Open access Research Article 10.9734/ibrr/2022/v13i330178

Three-way Complex Variant Translocation Involving Long Arm of Chromosome 1 in a Chronic Myeloid Leukemia Patient

Syeda Ambareen Zehra, Mamona Mushtaq, Azfar Ahmed & Neelum Mansoor · International Blood Research & Reviews · 2022

Clinical presentation of chronic myeloid leukemia (CML) with classic translocation is similar to those with variant translocations. However, the disease course, outcome and prognosis differs to a large extent. Therefore, it is important to identify and report variant cytogenetic...

Open access Research Article 10.9734/ibrr/2022/v13i330177

Effect of H. Pylori on Fibrinogen Level among Sudanese Patients at Khsartoum State

Nahla Mohammed Alias & Mubarak Saeed Mustafa Elkarsany · International Blood Research & Reviews · 2022

Background: Helicobacter pylori (H. pylori) is a gram-negative, spiral shaped pathogenic bacterium that specifically colonizes the gastric epithelium causing chronic gastritis, peptic ulcer disease, and/or gastric malignancy. Aim: To assess the effect of H. pylori on fibrinogen l...

Open access Research Article 10.9734/ibrr/2022/v13i330176

Effect of H. pylori among Diabetic Patients Living in Khartoum State, Sudan

Nahla Mohammed Alias & Mubarak Saeed Mustafa Elkarsany · International Blood Research & Reviews · 2022

Background: Studies suggest an association between Helicobacter pylori (H. pylori) infection and extra gastrointestinal disease. Limited studies provided conflicting results on the association between H. pylori infection and diabetes. The present study was aimed at examining the...

Open access Research Article 10.9734/ibrr/2022/v13i330175

Evaluation of Some Haematological Parameters in the Management of HBV Infection Treatment Outcome in Delta State, Nigeria

Sylvia Ifeoma Obu, Grace Ifechukwudelu Amilo, Nancy Chiatogu Ibeh, Alfred Friday Ehiaghe, Rebecca Chinyelu Chukwuanukwu, Agiande Oscar Unimnebeshi, Osakue Omoyemen Nosahkare, Samuel Ogenyi, Joy Imuetiyan Ehiaghe & Usiosefe Raphael Erhunmunse · International Blood Research & Reviews · 2022

Aims: To evaluate Hepatitis B virus (HBV) infection treatment outcome using the levels of white blood cells, haemoglobin, platelets counts and other red cell indices of HBV positive treatment naïve, on treatment at 3- and 6-months subjects attending gastro-enterology clinic in Fe...

Open access Research Article 10.9734/ibrr/2022/v13i230174

Study on Malaria and Haemoglobin Interaction in Pregnant Women

Konne Oroma Ethel, Moore-Igwe Beatrice Wobiarueri, Chukwu Priya Homa, Chukuigwe-Igbere Orokwu Eziaku, Konne Joel Burabari & Konne Felix Eedee · International Blood Research & Reviews · 2022

Comparative observational study was carried out on the prevalence of malaria among pregnant women attending antenatal clinics in General Hospital, Bori (GHB) and Braithwaite Memorial Specialist Hospital, Port Harcourt (BMSH).  Four hundred women were involved in this study of whi...

Open access Research Article 10.9734/ibrr/2022/v13i230172

Hematological Profiles of Eligible Blood Donors at Kenyatta National Hospital, Kenya

John K. Njenga, Nelson C. Menza, Scholastica G. Mathenge & Jesse N. Githanga · International Blood Research & Reviews · 2022

Aim: To determine hematological profile of eligible blood donors at Kenyatta National Hospital (KNH), Kenya. Study Design: Adopted a cross-sectional study. Place and Duration of Study: Kenyatta National Hospital, between March 2021 and August 2021. Methodology: This study recruit...

Open access Research Article 10.9734/ibrr/2022/v13i230173

Serum Hepcidin Level among Chronic Kidney Disease Subjects Accessing Healthcare in Braithwaite Memorial Specialist Hospital Port Harcourt

Lenox-Prince, Tamunonengiye-Ofori, Eze Evelyn Mgbeoma, Mordi, Augustina Ngozi & Jeremiah, Awortu Zacchaeus · International Blood Research & Reviews · 2022

Hepcidin is the major controller of systemic iron homeostasis and the role of the kidney in regulating hepcidin level is vital in the whole process of iron and hepcidin relationship. This study was aimed at evaluating serum Hepcidin level among Chronic Kidney Disease subjects acc...

Open access Research Article 10.9734/ibrr/2022/v13i230171

Occurrence Rate of Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Co - infection among Expectant Mothers Attending Antenatal Clinic in Rivers State University Teaching Hospital

Beatrice Wobiarueri Moore-Igwe, Beauty Eruchi Echonwere –Uwikor, Ransom Baribefii Jacob & Emmanuel-Nath Ogochukwu · International Blood Research & Reviews · 2022

The global burden of co-infection with human immunodeficiency virus (HIV), hepatitis B and C virus (HBV and HCV) has a negative impact in Sub-Saharan Africa.When HIV, HBV and HCV co-exist, they become life threatening and with high fatality rate particularly in gestation in which...

Open access Research Article 10.9734/ibrr/2022/v13i230170

Aberrant Expression of CD19 in Early T-cell Precursor Lymphoblastic Leukemia- A Diagnostic Challenge

Neelum Mansoor, Sidra Maqsood & Sumera Shaikh · International Blood Research & Reviews · 2022

A systematic approach is required to diagnose acute leukemia. Most of the cases are satisfactorily diagnosed and categorized into subtypes. However, a few cases pose diagnostic dilemma secondary to immunophenotypic aberrancies which are defined as antigens that are normally restr...

Open access Research Article 10.9734/ibrr/2022/v13i130169