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All published articles 379

An Investigative Study of Prothrombin Time, Activated Partial Thromboplastin Time and Antithrombin Levels in Patients with Ischaemic Stroke

Oluomachi C Nnachi, Innocent P Ezenwenyi, John C Akulue, Oji A Nnachi, Favour E Nwadum, Tochukwu J Onoh, Ozioma E Ezeokoli & Chima G Ugwu · International Blood Research & Reviews · 2024

Background: The haemostatic system maintains a balance between prothrombotic and antithrombotic components in the body. The role of this system in ischaemic stroke is not certain. Objective: Prothrombin time (PT) and Activated Partial Thromboplastin Time(APTT) are widely used scr...

Open access Research Article 10.9734/ibrr/2024/v15i3341

Sonographic Evaluation of Carotid Intima-Media Thickness and Iron Status of Regular and First-Time Blood Donors in a Tertiary Hospital in South-West Nigeria

Okeke O. F., Adeyomoye A. A. O., Akanmu A. S., Nwanna-Otolehi O. C. & Iyizoba G. · International Blood Research & Reviews · 2024

Background:  Regular blood donation which decreases blood iron levels may protect against cardiovascular diseases (CVD). This protection against atherosclerosis can be assessed by Carotid Intima-Media Thickness (CIMT) a biomarker for atherosclerosis. This study sought to determin...

Open access Research Article 10.9734/ibrr/2024/v15i3340

Positive Outcome in a Pregnancy with Anti-kell Alloimmunization Treated with Intravenous Immunglobulin and Therapeutic Plasma Exchange Despite Persistence of High Titre Antibody: A Case Report

Cinzia Vio, Anna Colpo, Luca Collodel, Piero Marson & Gianluca Gessoni · International Blood Research & Reviews · 2024

Background: Few reports have been published about  the current clinical management of anti-Kell alloimmunization in pregnancy; its low frequency of occurrence means that the few long series published have covered an extensive time period in which different treatment approaches ha...

Open access Research Article 10.9734/ibrr/2024/v15i3339

Pattern, Complications and Social Problems of Blood Transfusion in the Neonatal Unit of a Tertiary Hospital in Southern Nigeria

Boma Awoala West & Woroma Wonodi · International Blood Research & Reviews · 2024

Introduction: Blood transfusion is a life-saving procedure best carried out as soon as it is recommended to avoid morbidity and mortality. Aim: To determine the Pattern, complications and social problems of blood transfusion in a neonatal unit in Southern Nigeria. Methodology: A...

Open access Research Article 10.9734/ibrr/2024/v15i2338

RHD Genotyping to Resolve Weak and Discrepant RHD Phenotypes: The “Serenissima” Experience

Luca Collodel & Gianluca Gessoni · International Blood Research & Reviews · 2024

Background: A considerable number of RHD alleles responsible for weak and partial D phenotypes have been identified. Serological determination of these phenotypes is often doubtful and makes genetic analysis of RHD gene highly desirable in transfusion recipients and pregnant wome...

Open access Research Article 10.9734/ibrr/2024/v15i2337

Evaluation of Blood Transfusion Request form: The Experience in a Tertiary Health Facility in Jos, Nigeria

Jatau ED, Iheanacho CU, Okeke CN, Zakari A, Bangalu DY, Damulak OD & Egesie OJ · International Blood Research & Reviews · 2024

Background: There is a thin line between a safe blood transfusion and transfusion-related fatality hence the need to be diligent in every aspect of the blood transfusion process. Appropriate and complete documentation on a blood transfusion request form is one of the most importa...

Open access Research Article 10.9734/ibrr/2024/v15i2336

Antioxidant Effects of Vitamin C on Some Hematological Parameters of Male Wistar Rats Exposed to Lead Acetate

S.O Ojeka, Blessing Ukoro & Ebebi Elizah Onwoke · International Blood Research & Reviews · 2024

The study investigated the effects of vitamin C on platelet parameters, white blood cell count and white blood cells differentials in Wistar rats exposed to lead acetate. A total of twenty-four male Wistar rats weighing between 160g and 200g were utilized. The experimental animal...

Open access Research Article 10.9734/ibrr/2024/v15i2335

Interference of Heterophilic Antibody in D-dimer Determination in an Asymptomatic Elderly Woman

Valverde Sara, Masiero Elena, Seguso Mara, Giordano Martina, Inglese Margherita & Gessoni Gianluca · International Blood Research & Reviews · 2024

Background: D-Dimer is considered a pivotal biomarker in diagnosis of disseminated intravascular coagulation and in differential diagnosis of thrombosis and pulmonary embolism. Case Summary: BL, Caucasian woman, 81 years old, was admitted to hospital, in October 2023, for concuss...

Open access Research Article 10.9734/ibrr/2024/v15i2334

Study of Factor VIII Inhibitor and F8 Gene Mutations in Persons with Hemophilia A from Benin

Tatiana Baglo, Alban Zohoun, Bienvenu Houssou, Romaric Massi, Charlotte Orou Guiwa, Ludovic Anani, Dorothée Kindé Gazard & Awa Omar Touré Fall · International Blood Research & Reviews · 2024

Aim: determine the prevalence of a FVIII inhibitors and identify the genetic mutations associated with their development in beninese personne with hemophilia (PwH) A. Study Design: this is cross-sectional descrptive study conducted from June 2022 to May 2023 in hemophilia treatme...

Open access Research Article 10.9734/ibrr/2024/v15i1333

Evaluation of the Biological Response to Acetylsalicylic Acid by Platelet Occlusion Time in Pregnant Women in Brazzaville

LT Ocko Gokaba, JA Elira Samba, OF Galiba Atipo-Tsiba, GRJ Buambo, LO Ngolet, RC Iwandza, P Issongo Amboulou, J Nziengui Mboumba, C Bango, C Itoua & A Elira Dokekias · International Blood Research & Reviews · 2024

Low-dose acetylsalicylic acid (ASA) has been recommended for pregnant women since 2011 by the OMS to prevent thrombotic phenomena. Despite the variability of its clinical efficacy (resistance phenomena), its non-standardized biological monitoring can be performed using platelet o...

Open access Research Article 10.9734/ibrr/2024/v15i1331

An Assessment of the Viability of Haematological and Haemostatic Parameters of Blood under certain Storage Conditions at the Rivers State University Teaching Hospital Blood Bank in Port Harcourt, Nigeria

Nwika Goodnews Nkabari, Eze Evelyn Mgbeoma, Azuonwu Obioma & Ken-Ezihuo Stella U. · International Blood Research & Reviews · 2024

Introduction: Despite significant advances in transfusion medicine, concerns about the inherent risks of blood transfusion persist, even under optimal temperature and duration of storage. This makes the evaluation of blood viability a global task (1). Maintenance of adequate temp...

Open access Research Article 10.9734/ibrr/2024/v15i1329

Maternal Hemoglobin Levels as a Causative Factor in Incidence of Low Birth Weight Babies: A Public Health Prospective

Ekarini Daroedono, Aurelia Evina Haloho & Restu Fatimatuzzahra · International Blood Research & Reviews · 2023

Aims: To analyze some aspects of the maternal and the newborn in the incidence of low birth weight babies (LBWB). Study Design: simple retrospective with cross-sectional design approach. Place and Duration of Study: Retrospective data of LBWB obtained from newborn medical record...

Open access Research Article 10.9734/ibrr/2023/v14i4328

Secondary Erythrocytosis, a Predominant Cause of Polycythemia- Clinical and Laboratory Evaluation of Polycythemia in a Tertiary Care Center

Zunaira Aamir, Mamona Mushtaq & Sumera Sheikh · International Blood Research & Reviews · 2023

Aims: Polycythemia refers to an increased production of red blood cells from bone marrow. It is one of the frequent reasons for a hematology consultation. The present work aimed to examine the causes, clinical manifestations, prevalence, and diverse patterns in laboratory and cli...

Open access Research Article 10.9734/ibrr/2023/v14i4327