Skip to content

All published articles 379

Microbicidal Activity of Neutrophils Isolated from HIV Patients

J. B. Borges, T. Sakurada Jr, N. C. S. Santana, N. A. Lima, S. Lautenschlaugher & A. R. T. Pupulin · International Blood Research & Reviews · 2015

HIV infection is associated with a progressive loss of T cell functional capacity and reduced responsiveness to antigenic stimuli. Neutrophils are crucial cellular components of the innate immune system. Current study evaluates the functional activity of neutrophils isolated from...

Open access Research Article 10.9734/IBRR/2015/16929

Laboratory Accuracy of Some Human Immunodeficiency Virus Screening Methods in a Nigerian Blood Bank: Is it time for Universal Adoption of Enzyme-linked Immuno-Sorbent Assay Methodologies as the Minimum Testing Paradigm?

Orkuma Joseph Aondowase, Gomerep Simji Samuel, Egesie Julie Ochaka, Orkuma Jenifer Hembadoon, Mbaave Tsavyange Peter & Onoja Anthony Michael · International Blood Research & Reviews · 2015

Aim: To compare the prevalence rates, relevant indices of laboratory accuracy and proportion of false negative test results for some WHO recommended methodologies used for HIV screening amongst blood donor sata hospital-based blood bank in Nigeria. Study Design: A cross-sectional...

Open access Research Article 10.9734/IBRR/2015/17095

Epidemiological and Biological Parameters of Monoclonal Plasma Cell Dyscrasias in Thirty One Patients Consulting a Moroccan Pasteur Institute

Ilham Zahir & Abderahman Bellik · International Blood Research & Reviews · 2015

Aims: To describe epidemiological and biological features of patients with monoclonal plasma cell dyscrasias. The patients were seen at the Moroccan Pasteur Institute in Casablanca during a period of two years and four months. Place and Duration of Study: Laboratory of immunochem...

Open access Research Article 10.9734/IBRR/2015/15692

A Case Report of Pregnant Woman with Aplastic Anemia: Diagnosis and Management through Subsequent Pregnancy

Harshini Vana, J. B. Vidyashree, Mangala Gowri & Renuka Ramaiah · International Blood Research & Reviews · 2015

Introduction: Aplastic anemia is characterized by decreased bone marrow function with inadequate production of erythrocytes, granulocytes, and platelets. Marrow failure may be caused by absence of or defects in hematopoietic stem cells, abnormalities of the bone marrow microenvir...

Open access Research Article 10.9734/IBRR/2015/15735

Effect of Calpurnia aurea Seed Extract on HAART Induced Haematotoxicity in Albino Wistar Rats

Haile Nega Mulata, Natesan Gnanasekaran, Umeta Melaku & Seifu Daniel · International Blood Research & Reviews · 2015

Aim: To investigate the effect of Calpurnia aurea seeds extract on highly active antiretroviral therapy (HAART), first phase regimens (Lamivudine + Efavirenz + Zidovudine) induced heamtotoxicity in rats. Study Design: Thirty adult healthy male albino wistar rats of weighing about...

Open access Research Article 10.9734/IBRR/2015/15888

Appropriateness of Use of Blood Products in Tertiary Hospitals

Jerold C. Alcantara, Ann P. Opiña & Rhashani Arjay M. Alcantara · International Blood Research & Reviews · 2015

Aims: This study aimed at evaluating the appropriateness of use of blood products in Northern Philippines and sought to find out if significant differences exist on the appropriateness of use of the blood products among the different departments and the tertiary hospitals. Method...

Open access Research Article 10.9734/IBRR/2015/15852

Blood Coagulation Tests and Platelets Counts in Diabetic Rats Treated with Ficus sur, Jatropha tanjorensis, Mucuna pruriens and Chromolaena odorata Leaf Extracts

Ijioma Solomon Nnah · International Blood Research & Reviews · 2015

Aim: This study was designed to study the effects of leaves extracts of four indigenous Nigerian medicinal plants namely- Ficus sur, Jatropha tanjorensis, Mucuna pruriens and Chromolaena odorata on platelets counts and blood coagulation tests (bleeding and clotting times) in allo...

Open access Research Article 10.9734/IBRR/2015/14602

AML with Additional Cytogenetic Abnormalities to t(8: 21) has Poorer Survival than that with Isolated t(8;21): A Retrospective Multicenter Cohort Study

Nahla Ahmad Bahgat Abdulateef, Manar Mohammad Ismail, Soha Aly Elmorsy, Aziza F. ALswayyed, Essam Hamed Abdou & Omima Elemam · International Blood Research & Reviews · 2015

Aim of the Study: To investigate the poor prognostic factors incriminated in AML with t (8; 21), particularly additional cytogenetic findings, clinicopathological presentation and their impact on survival rate in Egyptian and Saudi patients. Study Design: Patients were collected...

Open access Research Article 10.9734/IBRR/2015/15529

A Probe into Protective Association of Haemoglobin Genotypes with Malaria Parasitaemia among Students of a University in Western Delta, Nigeria

F. D. Otajevwo & T. O. Enabulele · International Blood Research & Reviews · 2014

Aim: This work was designed to investigate any possible protective association of haemoglobin genotypes with malaria parasitaemia among students of a private University in Western Delta. Study Design: Whole blood samples were obtained from a cross section of students by simple ra...

Open access Research Article 10.9734/IBRR/2015/8923

Lipid Profile as a Marker of Pre-stage Cancer and Oral Cancer in Tobacco Users

D. Ayesha Thabusum, R. Sudhakara Reddy, T. Ramesh & N. Rajesh · International Blood Research & Reviews · 2014

Aim: To investigate the serum lipid profile in conventional smokers, reverse smokers and tobacco chewers and smokers and chewers associated with precancer and oral cancer. Study Design: A cross sectional longitudinal study. Place and Duration of Study: Department of Oral medicine...

Open access Research Article 10.9734/IBRR/2015/14140

Newly Exposed Membrane Glycoprotein II β (CD41) on Activated Platelets has Higher Affinity for Plasma Fibrinogen that Blocks Anti-CD41 Binding

Anugya Bhatt & Lissy K. Krishnan · International Blood Research & Reviews · 2014

The density of glycoprotein receptors on platelet membrane is dynamic and increase upon platelet activation by various stimulants to facilitate more ligand binding and functional outcome. Since CD41/61 receptor complex is responsible for platelet to platelet cross-linking, infusi...

Open access Research Article 10.9734/IBRR/2015/13147

Immunological and Hematological Profiles of Human Immunodeficiency Virus Positive Patients on Antiretroviral Treatment Followed at Institute Pasteur of Ivory Coast

A. F. J. Trébissou, C. C. A. Yapo-Crezoit, F. A. Yapo, A. Yéo, F. H. Yapi & J. A. Djaman · International Blood Research & Reviews · 2014

Aims: The immune system and some of the organs of HIV positive patients may be subject of some disruptions caused by Anti-Retroviral Treatment (ART). This study has been initiated in order to assess the impact of ART on the immunological and hematological parameters of People Liv...

Open access Research Article 10.9734/IBRR/2014/11109

An Immunohistochemical Study of PRAME Expression in Non-hodgkin’s Lymphoma

Semra Paydas, Arbil Avci Acikalin, Melek Ergin, Berna Bozkurt Duman & Gulsah Seydaoglu · International Blood Research & Reviews · 2014

Aim: Preferentially expressed antigen of melanoma (PRAME) is a cancer-testis antigen with very low/no expression in normal tissues. PRAME is an important target for tumor immunotherapy. Prognostic and in some tumors predictive importance of this expression have been shown in some...

Open access Research Article 10.9734/IBRR/2014/8832

Haematological Changes Associated With Hepatitis E Virus Seropositivity among Human and Animal Subjects in Plateau State, Nigeria

S. A. Junaid & S. E. Agina · International Blood Research & Reviews · 2014

Aim: To investigate the haematological manifestations of Hepatitis E Virus (HEV) seropositivity. Study Design: Cross sectional study. We included 592 subjects in the study; (426 humans and 166 animals). Humans were categorized into 4 groups: apparently healthy (190), pregnant wom...

Open access Research Article 10.9734/IBRR/2014/10273

Higher Ratio of Arterial vs Venous Thrombosis in Hemophilia A as Compared with Von Willebrand Disease

A. Girolami, E. Cosi, L. Sambado, V. Daidone & F. Fabris · International Blood Research & Reviews · 2014

Objectives: to investigate the ratio between arterial and venous thrombosis in patients with Hemophilia A or B in comparison with that of patients with von Willebrand Disease. Methods: analysis of a time unlimited survey of the literature together with an evaluation of personal r...

Open access Research Article 10.9734/IBRR/2014/11142