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All published articles 379

Congenital Dyserythropoietic Anaemia Type II: A Rare Blood Disorder in a Nigerian Child

Kaladada I. Korubo & Boma A. West · International Blood Research & Reviews · 2019

The congenital dyserythropoietic anaemias (CDA) are a rare group of inherited haematological disorders characterized by congenital anaemia, ineffective erythropoiesis in the bone marrow and dysplasia in developing erythroblasts. In Africa where sickle cell anaemia and thalassaemi...

Open access Research Article 10.9734/IBRR/2019/46976

Role of Dietary Calcium in Hypertension

Mariam Omar, Faiza Nouh, Manal Younis, Moftah Younis, Nesma Nabil, Sara Saleh, Sahar Ibraik & Areej Ali · International Blood Research & Reviews · 2019

Calcium level is an importance factor for control hypertension.  This review tries to shade the light on the role of calcium in controlling blood pressure. Searching on the internet using the Google search engine was the main source of data as well as books was the method to expl...

Open access Research Article 10.9734/IBRR/2019/46453

Hepatoprotective Potentials of Ethanolic Extract of Solanum melongena Linn Fruit on Monosodium Glutamate- Intoxicated Rats' and Liver Section Histology

Uchendu O. Mbah, Anthony Cemaluk C. Egbuonu, Ngozi K. Achi, Ijere D. Nwanne & Obinna Jeremiah · International Blood Research & Reviews · 2018

This study evaluated the hepatoprotective potentials of ethanolic extract of Solanum melongena Linn fruit on monosodium glutamate-intoxicated rats and liver section histology using standard protocols. Twenty four Wistar rats that weighed 105.00 ± 7.00 g were divided into 6 groups...

Open access Research Article 10.9734/IBRR/2019/45935

Overt Clinical Hypereosinophilia in T- cell Non Hodgkin Lymphoma: A Case Report

Chinmayee Agrawal, Kunal Das, Sanjiv Kumar Verma, Nadia Shirazi & Mansi Kala · International Blood Research & Reviews · 2018

The study describes a case of hyper-eosinophilia who was presented with overt manifestation of high eosinophil and detected to have underlying non Hodgkin lymphoma. The male patient was presented with profound weakness and multiple non itchy nodular skin lesion for 2 weeks. Biops...

Open access Research Article 10.9734/IBRR/2019/45392

Multiple Myeloma Relapse Presenting as Unilateral Blindness

Amit Badola, Tanvi Khanna, Kunal . & Sanjiv Kumar Verma · International Blood Research & Reviews · 2018

Multiple Myeloma is a chronic disease. While therapy is largely focused for control, relapse is inevitable. Central nervous system relapse of myeloma is less common. Unilateral painless blindness is a rare entity and its occurrence in the setting of multiple myeloma has not been...

Open access Research Article 10.9734/IBRR/2018/45424

Utility of Placental Umbilical Cord Blood in Autoimmune and Degenerative Disorders

Maimuna Khatoon, Jyoti Bindal, Dharmesh Chandra Sharma, Prakriti Gupta, Ashok Singh Tomar, Khozema Saify & Rakesh Gupta · International Blood Research & Reviews · 2018

Background: Umbilical cord blood is whole human blood (60 to 80 ml) that remains in the placenta and umbilical cord after childbirth; generally considered as a medical waste. It is a rich source of stem cells, growth factor, cytokines, etc., and, can be collected, stored and util...

Open access Research Article 10.9734/IBRR/2018/45260

Comparison of Human Erythrocyte Filterability with Trapping Rate Obtained by Nickel Mesh Filtration Technique: Two Independent Parameters of Erythrocyte Deformability

Takeshi Arita, Mitsuhiro Fukata, Toru Maruyama, Keita Odashiro, Takehiko Fujino, Chizuko Wakana, Aya Sato, Kazue Takahashi, Yoshiko Iida, Shiro Mawatari & Koichi Akashi · International Blood Research & Reviews · 2018

Background: Erythrocyte deformability is a major determinant of microcirculation in vivo. Although this concept was defined as filterability evaluated by flow-pressure curve constructed during a filtration process of erythrocyte suspension through a nickel mesh filter, the behavi...

Open access Research Article 10.9734/IBRR/2018/44667

Comparative Investigation of the Effects of Different Aqueous Preparations of Hibiscus sabdariffa (Zobo Drinks) on Haematological Parameters in Normal Wistar Albino Rats

Chukwu, Charles Nnanna, Ikewuchi, Catherine Chidinma & Akaninwor, Joyce Oronne · International Blood Research & Reviews · 2018

Aim: Investigating and comparing the effect of administration of different preparations of the commonly-consumed Hibiscus sabdariffa Linn (Zobo) drinks on haematological parameters. Study Design: Comparative study using animal models (Wistar Albino Rats) with daily administration...

Open access Research Article 10.9734/IBRR/2018/26076

Haemostatic Disorders in Sickle Cell Disease Subjects in Nigeria: A Review of Literature

Kingsley Akaba, Marcus Inyama, Timothy Ekwere, Obinna Iheanacho, Ekpeyong Bassey, Ushie Godwin, Hogan Archibong & Efiok Efiok · International Blood Research & Reviews · 2018

Background: Sickle cell disease (SCD) is an autosomal recessive disorder that is characterised with chronic anaemia and painful crisis. SCD is associated with hypercoagulability or prothrombotic state that can predispose to thromboembolic complications with increasing morbidity a...

Open access Research Article 10.9734/IBRR/2018/43929

Hematological Assessment of Benzene Exposure among Employees in Brega Oil Marketing Company (BOMC), Benghazi

Huda Mohamed, Maha A. Swani, Majdeddin. I. Alaghib, Abdeljawad I. Abdeljawad, Murad Alkezza & Mohamed Alobaidy · International Blood Research & Reviews · 2018

Background:  Benzene is a toxic chemical and is a human carcinogenic. It is found in both the natural and industrial atmosphere. Its exposure can cause hematological health problems as a result of metabolite formation in the liver and bone marrow. The aim of this study is to eval...

Open access Research Article 10.9734/IBRR/2018/43266

Impact of DNMT3A Gene Mutation on Response of Acute Myeloid Leukemia Patients to Induction Therapy

Dina G. Segai, Nevene Ramsis, Hanaa Fahmy & Noha Kamel · International Blood Research & Reviews · 2018

Aim: To evaluate the frequency and prognostic impact of DNA methyltransferase 3A (DNMT3A) gene mutation on response to induction therapy in newly diagnosed acute myeloid leukemia patients. Study Design: Cross-sectional descriptive study. Place and Duration: Hematology units of Su...

Open access Research Article 10.9734/IBRR/2018/44030

Seroprevalence of Salmonella Agglutinins among Apparently Healthy Students of a Tertiary Institution in North-Eastern Nigeria

M. Y. Tula, O. Iyoha, R. O. Okojie, J. Filgona & G. A. Onyeje · International Blood Research & Reviews · 2018

Aim: To determine the level of Salmonella agglutinin and its titre among apparently healthy students of Tertiary Institution in North-eastern Nigeria. Study Design: A cross-sectional study on Seroprevalence of Salmonella agglutinin; Place and Duration of the Study: Department of...

Open access Research Article 10.9734/IBRR/2018/43362

FLT3 Mutations: Significance in Paediatric AML

Salma M. Aldalal · International Blood Research & Reviews · 2018

Patients with acute myeloid leukaemia (AML) who have FMS-like tyrosine kinase 3 (FLT3) mutations are a concern for haematologists. Many studies indicate that these patients have poor prognosis. Due to the dearth of research in this area, the role of allogeneic transplantation as...

Open access Research Article 10.9734/IBRR/2018/42466

The Frequency and Distribution of ABO Blood Groups in Patients with Haematological Cancers in Uyo, Nigeria: A Hospital Based Retrospective Study

Mabel Benson Ino-Ekanem, Timothy Amos Ekwere & Anyiekere Morgan Ekanem · International Blood Research & Reviews · 2018

Background: The pattern and distribution of haematological malignancies vary depending on age, sex and geographical location. Studies on the association between haematological cancers and ABO blood types have been largely conflicting. Aim: To determine the frequency and distribut...

Open access Research Article 10.9734/IBRR/2018/42665

Bacterial Contamination of Blood and Blood Components: Reducing the Risks in Nigeria

O. E. Busari, O. T. Ojo & T. S. Akingbola · International Blood Research & Reviews · 2018

Introduction: Administration of blood and blood products is very life-saving. However, the safety of blood transfusion in resource-limited nations is questionable unlike in many developed nations of the world. The risk of viral transmission has been significantly curtailed, but b...

Open access Research Article 10.9734/IBRR/2018/42233