Purpose: Splenectomy is used as the second line therapy in patients with immune thrombocytopenia (ITP). However, there is no parameter predicting splenectomy decision. Thrombopoietin is the main regulator of platelet count through its receptor c-mpl. The aim of the present study...
Open access
Research Article10.9734/ibrr/2019/v9i430107
Background: Platelet aphaeresis is an essential procedure, which meets the demand of single donor platelets (SDP) effectively. The procedure is well tolerated by donors with fewer side effects. Adverse events in Platelet aphaeresis have been reported from as low as 0.32 to 6.81%....
Open access
Research Article10.9734/ibrr/2019/v9i430106
Aim: This study was carried out to evaluate the effect of ethanol extract of Aju Mbaise herbal mixture on some haematological indices of diabetic Wistar albino rats. Sample: Packed cell volume (PCV) and haemoglobin (Hb) concentration was estimated in diabetic rats treated with et...
Open access
Research Article10.9734/ibrr/2019/v9i430105
Aim: The study is aimed at investigating the antinutritive effects of aqueous root extract of Moringa oleifera on haematological indices following sub-chronic consumption of alcohol in Wistar rats. Methods and Materials: Thirty (30) experimental rats weighing 100-120 g were rando...
Open access
Research Article10.9734/ibrr/2019/v9i430104
Background: Viral hepatitis is a global health problem with 170 million Hepatitis C Virus (HCV) carriers worldwide, and 12-13 million HCV carriers in India. Unscreened blood and components play a significant role in transmission of HCV apart from reuse of injection needles, unste...
Open access
Research Article10.9734/ibrr/2019/v9i330103
Background: Blood transfusion service is an indispensable component of health care. Despite the increased demand for blood, the supply of safe blood has been inadequate. Objective: The aim of this study is to determine the pattern of blood donation practices among medical student...
Open access
Research Article10.9734/ibrr/2019/v9i330102
Aim: This study assessed the level of plasma haemoglobin concentration in CPDA-1 stored blood with a view to determine the extent of haemolysis during the 35 days storage period. Study Design: This is an observational and comparative case-control study. Place and Duration of Stu...
Open access
Research Article10.9734/ibrr/2019/v9i330101
Nweje- Anyalowu Paul Chukwuemeka, Anyalogbu Ernest Anayochukwu Aniemeka, Idakwoji Precious Adejoh, Agatemor Uzuazokaro Mark-Maria & Uroko Robert Ikechukwu·International Blood Research & Reviews·2019
Objective: This study was undertaken to validate the haematinic potentials of the aqueous leaf extracts of Ficus exasperata (FEAE) and Telfeira occidentalis (TOAE) administered separately and to establish a possible synergistic interaction when administered concurrently to chlora...
Open access
Research Article10.9734/ibrr/2019/v9i330100
Zidovudine administration either in single or fixed-dose combination usually results in a decrease in body weight and in some cases thrombocytopenia. The present study investigated the body weight and platelet count changes observed in zidovudine pre-administered Wistar albino ra...
Open access
Research Article10.9734/ibrr/2019/v9i330099
Introduction: The ABO blood group system is unique in immunology and haematology because it is the only system in which antibodies are consistently and predictably present in the serum of normal individuals whose red cells lack the antigens. Several epidemiological studies have r...
Open access
Research Article10.9734/ibrr/2019/v9i230098
Background: A number of processes regulating the thrombolytic balance are impaired in diabetic patients as a result of dysfunction of endothelial cells leading to a hypercoagulative state. Von Willebrand factor (VWF) is an important marker of endothelial dysfunction. Plasminogen...
Open access
Research Article10.9734/ibrr/2019/v9i230097
Iron deficiency anaemia is the most common nutritional deficiency disorder in children and is worldwide in distribution. It is characterised by fatigue, weakness, pallor and koilonychias. Thus oral physician play an important role in diagnosis and thereby prevention of anaemia, a...
Open access
Research Article10.9734/ibrr/2019/v9i230096
Sherine Samir Barakat, Manal Abd Elsatar Elsorady, Mona Wagdy Ayad, Dalia Abd Elmoety Elneely & Fatma Mohamed Abd Elfatah·International Blood Research & Reviews·2019
Background: Acute myeloid leukaemia (AML) is a malignancy that is heterogeneous in nature characterized by genetic abnormalities some of which are established in the diagnosis and prognosis of the disease. An additional role for alterations in epigenetic mechanisms has been also...
Open access
Research Article10.9734/ibrr/2019/v9i230095
Background: The haemostatic changes that result in thrombophilia during the pregnant state have been linked to pregnancy loss. Objective: Assessment of Protein S, and Protein C assays in pregnancy loss victims in Abia State, South East, Nigeria. Materials and Methods: This was a...
Open access
Research Article10.9734/ibrr/2019/v9i230094
Leucocytosis, marked increase in the number of white blood cells (WBC) is a known physiological response to trauma. In recent times, several studies have asserted the absence of this response in Africans. In view of this, current study investigated the existence of, and prognosti...
Open access
Research Article10.9734/ibrr/2019/v9i130093