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Mechanisms of Antiulcerogenic Effect of Garlic (Allium sativum) in Albino Rats

Salaudeen Aminat Tope, Oluwole Francis Sunday & Adedeji Temitope Gabriel · European Journal of Medicinal Plants · 2014

Aims: The aim of the present study was to investigate the possible effects of garlic juice, as well as feed supplemented with Allium sativum, on gastric ulceration, antioxidant activity and gastric mucus cell count in wistar rats. Study Design: The albino rats were divided into s...

Open access Research Article 10.9734/EJMP/2014/8140

Preliminary Investigation of the Anti-asthmatic Potential of Kalanchoe integra Leaf Extract Using a Model of Allergic Airway Inflammation

Asiedu- Gyekye Isaac Julius, Awortwe Charles, Tagoe Nii Aryee Benjamin, Antwi Daniel Ansong, Adjei Samuel, Edusei Dwamena Isaac, Benoit N’guessan Banga Kwame, Amoateng Patrick & Nkansah Edwin · European Journal of Medicinal Plants · 2014

Objective: Kalanchoe integra is known to possess antihistaminic and mast cell stabilizing effect. Inflammatory mediators, such as histamine and eicosanoids have been implicated in the pathophysiology of allergen-induced asthma including bronchospasm, vasodilation, increased vascu...

Open access Research Article 10.9734/EJMP/2014/7377

Lethality and Antioxidant Activity of some Sudanese Medicinal Plants’ Fixed Oils

Muna F. Abushama, Yasmin I. Hilmi, Haidar M. AbdAlgadir, Eltayeb Fadul & Hassan E. Khalid · European Journal of Medicinal Plants · 2014

The objective of the undergoing work is investigating antitumor therapy potential and antioxidant capacity of Sudanese medicinal plants Helianthus annuus L. (Asteraceae), Ricinus communis L. (Euphorbiaceae), Nigella sativa L. (Ranunculaceae), Sesamum indicum L. (Pedaliaceae) and...

Open access Research Article 10.9734/EJMP/2014/7741

Launaea taraxacifolia Ameliorates Cisplatin-Induced Hepato-renal Injury

A. S. Adejuwon, O. Femi-Akinlosotu, J. O. Omirinde, O. R. Owolabi & A. M. Afodun · European Journal of Medicinal Plants · 2014

Aims: The protective potential of aqueous leaf extract of Launaea taraxacifolia against Cisplatin-induced hepato-renal damage in Wistar rats. Study Design: Randomized controlled experiment Place and Duration of Study: Experimental Animal Unit and Department of Anatomy, University...

Open access Research Article 10.9734/EJMP/2014/7314

Demethylation of RARβ2 Gene Promoter by Withania somnifera in HeLa Cell Line

Abhimanyu Kumar Jha, Mohsen Nikbakht, Neena Capalash & Jagdeep Kaur · European Journal of Medicinal Plants · 2014

An important molecular target for cancer therapy is the possible reactivation of tumor suppressor genes that have been silenced by promoter methylation.  It was observed that the treatment of an adenocarcinoma cervical cancer cell line, HeLa with 20 µg/ml of the ethanolic extract...

Open access Research Article 10.9734/EJMP/2014/5975

Phytochemical Evaluation and Effect of Saponins’ Mixture Isolated from Astragalus monspessulanus on HepG2 Cell Line

Viktor Bratkov, Magdalena Kondeva-Burdina, Rumyana Simeonova, Virginia Tzankova & Ilina Krasteva · European Journal of Medicinal Plants · 2014

Aims: Purified saponin fraction was obtained from butanol extract of the aerial parts of Astragalus monspessulanus var. monspessulanus. The fraction was analyzed by HPLC and six saponins were determined. The saponin mixture was investigated for possible cytotoxicity on HepG2 cell...

Open access Research Article 10.9734/EJMP/2014/7860

Anti-pyretic Activity of Garcinia kola Seed Extract

Kakjing D. Falang, Mary O. Uguru & Nkoli L. Nnamonu · European Journal of Medicinal Plants · 2014

Garcinia kola (Heckel) has been used in folk medicine for the treatment of several ailments. One of these is its use for the treatment of conditions involving pain and inflammation with accompanying pyrexia. Our objective is to evaluate the anti-pyretic property of Garcinia kola...

Open access Research Article 10.9734/EJMP/2014/4484

In vivo Antiplasmodial Activity of the Stem Extracts of Balanites aegyptiaca (L) Delile

Sulaiman S. Rukayyah & Ali A. Jigam · European Journal of Medicinal Plants · 2014

Aims: To investigate in vivo antiplasmodial activity of the stem extracts of Balanites aegyptiaca (L) Del. Study Design: Animal model infected with Plasmodium berghei. Place and Duration of Study: Department of Biochemistry,  Federal University of Technology,  Minna, Niger State,...

Open access Research Article 10.9734/EJMP/2014/3982

Anti HIV-1 Activity of the Crude Extracts of Guaiacum officinale L. (Zygophyllaceae)

Henry I. C. Lowe, Ngeh J. Toyang, Alonso Heredia, Charah T. Watson & Joseph Bryant · European Journal of Medicinal Plants · 2014

Aim: Jamaica is rich in medicinal plants.  Guaiacum officinale is the “National Flower”, with reported uses in folk medicine for the treatment of various conditions including inflammation.  In our search for plants with anticancer and anti-infective properties, we evaluated Guaia...

Open access Research Article 10.9734/EJMP/2014/7343

Carcinogen Metabolizing Enzymes: Modulation of Their Activities in Liver, Lung and Stomach by Thymoquinone

Said Al-Dalaen, Samir Mahgoub & Aiman Al-Qtaitat · European Journal of Medicinal Plants · 2014

Background: Thymoquinone (TQ), the bioactive constituent of black seed (Nigella sativa), has been shown to inhibit the growth of various human cancerous cells both in vitro and in vivo. Aim: To characterize the effects of thymoquinone on the activity of phase I and phase II carci...

Open access Research Article 10.9734/EJMP/2014/3870

Germination Eco-physiology of Angelica glauca Edgew Seeds

J. S. Butola, R. K. Vashistha, C. P. Kuniyal, A. R. Malik, Aasif Ali & S. S. Samant · European Journal of Medicinal Plants · 2014

Aims: Angelica glauca Edgew is a heavily exploited critically endangered medicinal cum aromatic herb of Himalayan region. Poor and erratic seed germination is one of the constraints in its in-situ as well as ex-situ conservation and large scale cultivation. Moreover, our understa...

Open access Research Article 10.9734/EJMP/2014/7527

Standardization of Andrographis paniculata, Mitracarpus scaber and Nauclea latifolia Herbal Preparations as per European and Nigerian Drug Regulations

Sunday J. Ameh, Nneka Ibekwe, Aminu Ambi, Obiageri Obodozie, Mujtaba Abubakar, Magaji Garba, Herbert Cocker & Karniyus S. Gamaniel · European Journal of Medicinal Plants · 2014

Background: Herbal drug standardization (HDS) is multidisciplinary with botany and chemistry working together to facilitate decisions on production of herbal medicines. The common reasons for HDS are: i) it creates the need for establishing botanical identity; ii) it is necessary...

Open access Research Article 10.9734/EJMP/2014/5457

Nutritional Assessment and Mineral Composition of Some Selected Edible Vegetables

Najeeb Ur Rehman, Javid Hussain, Liaqat Ali, Abdul Latif Khan, Fazal Mabood, Syed Abdullah Gillani & Ahmed Al-Harrasi · European Journal of Medicinal Plants · 2014

Aims: The present study aimed to assess the nutritional significance of some of the commonly consumed vegetables collected from Hangu, Khyber Pakhtunkhwa, Pakistan. Study Design: The study was designed in randomized block design and each analysis was performed with three replicat...

Open access Research Article 10.9734/EJMP/2014/5271

Anti-ulcerogenic Effects and Anti-oxidative Properties of Ceiba pentandra Leaves on Alloxan-induced Diabetic Rats

C. A. Anosike, J. C.Ugwu, P. C. Ojeli & S. C. Abugu · European Journal of Medicinal Plants · 2014

Aims: To evaluate the protective effects of methanol extract of Ceiba pentandra leaves on indomethacin and ethanol induced gastric ulcer and on oxidative stress indices of alloxan-induced diabetic rats. Study Design: Extraction and administration of graded doses of the extract Pl...

Open access Research Article 10.9734/EJMP/2014/6479

Phytochemical and Anti-microbial Screening of the Leaves and Twigs of Sclerocarpus africanus (Jacq)

R. G. Ayo, J. A. Ndiombueze & T. A. Tor-Anyiin · European Journal of Medicinal Plants · 2014

Aim: To determine phytochemical constituents and antimicrobial activity of leaves and twigs of Sclerocarpus africanus (Jacq);  prove or otherwise  ethno-medicinal claims on S. africanus. Place and Duration of Study: Departments of Chemistry, Biological sciences and  Microbiology,...

Open access Research Article 10.9734/EJMP/2014/7096