The cytokines IFN-γ, interleukin IL-1β, and TNF-α each up regulate the expression of major histocompatibility complex (MHC) and are therefore considered as inflammatory markers. The present study aimed to measure the serum levels of IFN-γ, interleukin IL-1β, and TNF-α in mice aft...
Open access
Research Article10.9734/ijbcrr/2021/v30i130243
Background and Aim: Atherosclerosis is a chronic systematic disease where lesion (plaque) develops results in activation of inflammatory reaction that leads to arterial obstruction. Atherosclerosis is the underlying cause for many cardiovascular diseases (CVD) which were estimate...
Open access
Research Article10.9734/ijbcrr/2021/v30i130242
Mosquitoes are the most important group of insects in terms of public health importance, which transmit serious human diseases. The continuous application of synthetic insecticides to control these mosquitoes causes development of resistance in vector species, and an adverse effe...
Open access
Research Article10.9734/ijbcrr/2021/v30i130241
The bioactive components of Spondias mombin leaf have been evaluated using gas chromatography and mass spectroscopy (GC/MS). The plant were collected washed, shade dried and milled and the methanol extract of the leaf plant were prepared by soxhlet extract method. The methanol ex...
Open access
Research Article10.9734/ijbcrr/2021/v30i130240
Background and Objective: Disturbance in adrenocortical mechanisms of regulation can play a significant role in the development of metabolic syndrome (MS). The goal of the work was to study the correlations between the glucocorticoid status of patients with metabolic syndrome and...
Open access
Research Article10.9734/ijbcrr/2020/v29i930233
There are scientific reports of medicinal plants having curative properties. These properties may be due to the presence of various phytochemicals in the plants. Cassia alata is a specie in the Fabaceae family. The purpose of this study is to determine the antidermatophyte activi...
Open access
Research Article10.9734/ijbcrr/2020/v29i1030234
Combretum collinum root extract has been recognized long ago as traditional medicinal plant in curing several diseases among the indigenous people of Alela-land (Zuru), Kebbi State, Nigeria. This research work was carried out to evaluate the toxicological effects of Combretum col...
Open access
Research Article10.9734/ijbcrr/2020/v29i1030235
Aim: To analyze the RNA-dependent RNA polymerases (RdRps) of Severe Acute Respiratory Syndrome (SARS)-related coronaviruses (CoVs) to find out the conserved motifs, metal binding sites and catalytic amino acids and propose a plausible mechanism of action for these enzymes, using...
Open access
Research Article10.9734/ijbcrr/2020/v29i1030236
Background: Type 2 diabetes mellitus (DM) is the most common cause of end- stage renal disease. Albuminuria is the foremost commonly utilized marker to anticipate onset of diabetic nephropathy (DN) without sufficient affectability and specificity to identify early DN. Aim: This s...
Open access
Research Article10.9734/ijbcrr/2020/v29i1030237
Background: Type 2 diabetes mellitus (DM) is the most common cause of end- stage renal disease. Albuminuria is the foremost commonly utilized marker to anticipate onset of diabetic nephropathy (DN) without sufficient affectability and specificity to identify early DN. Aim: This s...
Open access
Research Article10.9734/ijbcrr/2020/v29i1030238
Objective: To investigate the association between plasma free amino acids (PFAAs) profile changes, vitamin D concentration and hypertension and evaluate the clinical utility of this association for nascent hypertension before the development of complications. Methods: 70 subjects...
Open access
Research Article10.9734/ijbcrr/2020/v29i930232
Corona virus-2 (nCOVID-19), causes respiratory infection including cold, fever, sneezing and coughing, pneumonia, headache, diarrhea and upper respiratory diseases. It transmitted human to human via airborne droplets. Corona virus enters in human cell through membrane ACE-2 exope...
Open access
Research Article10.9734/ijbcrr/2020/v29i930231
Alafia barteri leaves are valued for its efficacy in the traditional medicine system in Nigeria. It has been used over the years for the treatment of various diseases some of which include malaria, sickle cell anaemia, and eye infections. This has necessitated the evaluation of i...
Open access
Research Article10.9734/ijbcrr/2020/v29i930230
Several plants worldwide have exhibited potentiality in human pathogen eradication. The aim of this work was to characterize the compounds and determine antibacterial efficiency of Tithonia diversifolia essential oils and its iron II nanoparticles. The experimental test was done...
Open access
Research Article10.9734/ijbcrr/2020/v29i930229
Aims: To determine the effect of V. amygdalina on the levels of antioxidants and the liver of rabbits fed on a atherogenic diet. Study Design: Prospective experimental study. Place and Duration of study: Study lasted 14 weeks at Department of Anatomy, University of Ibadan, Nigeri...
Open access
Research Article10.9734/ijbcrr/2020/v29i930228