Aim: To evaluate the effect of diet containing Sesame Seed (Sesamum indicum) on some biochemical parameters in Diabetic albino Wistar Rats Study Design: Experimental study. Place and Duration of Study: Department of Biochemistry, University of Port Harcourt, Rivers State, Nigeri...
Aim: To assess the levels of some oxidative stress markers in humans exposed to pesticides in Okagwe and Ihe-Nta, Abia State, Nigeria. Study Design: A cross-sectional study. Place and Duration of Study: Abia-ADP, Ohafia Zone and Department of Biochemistry, University of Port Harc...
Tembe Fokunang Estella, Ndi Sirri Akwen, Mbong Grace Annih, Ashu Michael Agbor, Dobgima John Fomnboh, Tchadji Mayoudom Vanessa Edwige, Bayaga Herve, Njinkio Borgia Nono, Roger Zintchem, Yolande Gnagne Koffi & Charles Fokunang·International Research Journal of Gastroenterology and Hepatology·2022
Introduction: Peptic ulcer disease (PUD) is a major public health concern, affecting up to 10% of the world’s population. This disease results from an imbalance between the gastro protective and aggressive factors of the gastric mucosa. Prevalence of PUD is about 10% in Cameroon...
Background: The use of potash as food additive without a recourse to its adverse effect is on the increase in Nigeria. Aim: This study is designed to assess its effect on hepatic indices of Wistar rats. Methodology: Potash was locally sourced in a market in Owerri, Imo State, Nig...
Aim: The aim of this study was to evaluate chronic hepatotoxicity and oxidative stress induced by 2, 2-dichlorovinyl dimethyl phosphate (Sniper) in New Zealand white rabbits. Study Design: This is an experimental study. Place and Duration of Study: Department of Biological Scien...
Introduction: Hospitalization is a common experience today. According to the World Health Organization (WHO), in 2012, the global volume of surgical procedures performed was estimated at 312.9 million operations. Addition to the physical consequences of surgery, patients may also...
Objectives: Thrombocytopenia, a complication of Chronic Liver Disease (CLD), is considered to be a marker of advanced disease and an independent predictor of mortality. But this is disputable and hence is this study 1. To find out prevalence of thrombocytopenia in CLD; 2. To find...
Hepatic Cirrhosis is recognized by the formation of regenerative nodules in liver parenchyma bounded by fibrous septa consequent to chronic liver injury. Cirrhosis occurs because of necrosis of liver cells followed by fibrosis and nodule formation. The liver organization becomes...
Eosinophilic enteritis is a rare disorder, affecting human gastrointestinal tract (GIT). The exact etiology is unknown, and some drugs are implicated in causing this condition. We report a case of drug induced eosinophilic enteritis, caused by antituberculosis therapy (ATT). The...
Aim: The aim of the study was to evaluate the effect of Jathropha interrigima on hepatic function of male Albino Wistar rats exposed to lead. Study Design: The study is an experimental study. Place and Duration of Study: Department of Animal and Environmental Biology, Rivers Stat...
Aim: This study sought to evaluate the hepatoprotective potential of alkaloid extracts from V. doniana and F. thonningii leaves on alloxan-induced diabetic rats. Materials and Methods: Fresh leaves of V. doniana and F. thonningii were obtained from a local market Nkwagu in Abakal...
Aim: The aim of this study was to evaluate the biochemical changes in Rabbits due to Sodium Cyanide exposure. Study Design: An experimental study. Place and Duration of Study: This study was carried out at Animal House, Applied and Environmental Biology Department, Rivers State...
Aim: This study sought to investigate the effect of Bambara nut on hepatic biomarkers of Wistar rats. Methodology: The Songkhla 1 variety (red seed coat) of Bambara nuts were locally sourced in Obinze area of Owerri, Imo State, Nigeria. The seeds were peeled and ground to a fine...
Aims: hypovitaminosis D may be related to the pathogenesis of the nonalcoholic fatty liver disease (NAFLD) and may contribute to NAFLD's development and progression. Our study aimed to evaluate the therapeutic effects of vitamin D supplementation in patients with NAFLD. Place and...
Background: Xylopia aethiopica fruit has been reported to possess high medicinal value. Thus, people use it without any regard for its toxicity. Aim: This study is therefore aimed at investigating its toxicity on the liver of Wistar rats. Methodology: The fruits of Xylopia aethio...