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All published articles 154

Effect of Tramadol Hydrocholoride on the Biomarkers of Liver and Kidney Function and Oxidative Stress in Male Albino Rats

Halimatu S. Abdullahi, Ejiogu I. Chibueze & Joshua R. Kuje · International Research Journal of Gastroenterology and Hepatology · 2023

Background: Tramadol is an opioid-like analgesic or pain-relieving agent, used parenterally and orally for the treating moderate or severe painful sensation. Because the drug is inexpensive and is not classified as control drug by the government, the authors attempt to establish...

Open access Research Article

Single-Center Review of Appropriateness and Utilization of Upper GI-Endoscopy in Dyspepsia: A Retrospective Study

Kalpana Acharya, Neeraj Dhar & Syed Mushfiq Shafi · International Research Journal of Gastroenterology and Hepatology · 2023

Introduction: Upper GI Endoscopy is one among the most commonest tool used by gastroenterologists to define the etiology of dyspepsia. Is this the final decree for all dyspeptic patients or we have to change our decisions as per the resouce available? This study tried to look ove...

Open access Research Article

Evaluation of the Hepatotoxic and Nephrotoxic Potential of Methanol Leaf Extract of Lantana camara

Elizabeth Obioma Nweke, Ebere Lolly Mbanaso, Kelechi Collins Owuka, Precious Ebisintei & Ubani Clement Dimgba · International Research Journal of Gastroenterology and Hepatology · 2023

Owing to its extensive blood supply and significant role in metabolism, the liver is particularly susceptible to xenobiotics. Thus, it is exposed to high doses of the toxicant or toxic metabolites. The kidney is highly susceptible to toxicants because a high volume of blood flows...

Open access Research Article

Ultrasound Assessment of Pancreatic Dimensions in Normal Adults in South-South Nigeria

Enefia Kelvin Kiridi, Peter Chibuzor Oriji, Emily Gabriel Enefia Kiridi, Obiora Chibundu, Johnpatrick Uchenna Ugwoegbu & Obinna Isidore Onyia · International Research Journal of Gastroenterology and Hepatology · 2023

Background: The pancreas can be imaged using ultrasound to provide details on its size, echotexture, ductal anatomy, and surrounding tissues. Diagnostic and interventional procedures can be easily completed quickly and for a low cost. Objectives: To determine the normal pancreati...

Open access Research Article

Phytochemical Screening and Evaluation of the Anti Ulcer Activity of Dacryodes edulis (Burseraceae) Leaf Extracts in Wistar Rats

Nomo Honore, Tembe Estella Fokunang, Bayaga Herve, Njinkio Nono Borgia, Mbacham Wilfred & Charles Fokunang · International Research Journal of Gastroenterology and Hepatology · 2023

Peptic ulcer disease is a chronic condition of the gastrointestinal tract that results from an imbalance between protective and aggressive factors of the gastric mucosa. Many synthetic drugs are used for the treatment of this disease, but they are costly and exhibit limited effic...

Open access Research Article

Occurrence of Potential Bacterial Pathogens in Food from Local Restaurants in Azikoro Town, Bayelsa State, Nigeria

Douye Victor Zige & Ayibanua Ayibakeme · International Research Journal of Gastroenterology and Hepatology · 2023

Foodborne gastroenteritis, security and safety is a global concern in today’s world, in that regard it is a major concern to public health policies however foods vendor are patronized on daily bases in urban and suburban cities in Nigeria. This study is aimed at investigating the...

Open access Research Article

Isolation and Identification of Salmonella Species Associated with Febrile Patient Using Basic Molecular Techniques

Douye Victor Zige & Faith Iyeoma Omeje · International Research Journal of Gastroenterology and Hepatology · 2023

Salmonella enterica, serotype Typhi, remains the predominant Salmonella species causing enteric fever. This disease threatens public health as it is associated with personal hygiene techniques and practices. This study investigates Salmonella typhi using conventional bacteriologi...

Open access Research Article

Peptic Ulcer Disease; Stomach and Gastric Ulcers, a Concise Review

Ahtshamullah Chaudhry, Kimberly Morton Cuthrell & Owen R Thornton · International Research Journal of Gastroenterology and Hepatology · 2023

The most prevalent condition affecting the stomach and duodenum is peptic ulcer disease (PUD), which is linked to Helicobacter pylori (H. pylori) infection. Esophageal, duodenal, and stomach ulcers are all parts of peptic ulcer disease (PUD). Epigastric discomfort is the PUD symp...

Open access Research Article

Comparison of Portal Vein Diameter in Pregnant and Non-pregnant Women in South-south Nigeria

Enefia Kelvin Kiridi, Peter Chibuzor Oriji, Emily Gabriel Enefia Kiridi, Obiora Chibundu, Akaninyene Eseme Ubom, Obinna Isidore Onyia, Johnpatrick Uchenna Ugwoegbu, Panebi Yao Bosrotsi, Abednigo Ojanerohan Addah & Adedotun Daniel Adesina · International Research Journal of Gastroenterology and Hepatology · 2023

Background: The hepatic artery is a branch of the coeliac trunk, and supplies 25% of the total blood flow to the liver, while the portal vein is formed by the mesenteric and splenic veins, and accounts for the remaining 75% of hepatic blood supply. Objectives: To compare the port...

Open access Research Article

Current Updates on in vitro Dissolution Testing for Immediate Release Oral Dosage Forms

Mehedi Mala Mitu & Tirtha Nandi · International Research Journal of Gastroenterology and Hepatology · 2023

Immediate-release oral dosage forms, also known as IR dosage forms, have become a popular choice for administering medication due to their ability to dissolve at an accelerated rate. This means that the medication is quickly released into the bloodstream, providing fast relief to...

Open access Research Article

Surgery for Crohn's Disease: Experience in the Department of General Surgery: A Retrospective Study of 60 Cases

A. Bachar, N. Fakhiri, K. Falousse, T. El Abbassi & M. R. Lefriyekh · International Research Journal of Gastroenterology and Hepatology · 2022

Crohn's disease (CD) consists of segmental digestive inflammation and transmural, Sometimes associated to anoperineal and extradigestive manifestations. The clinical manifestations of our patients were varied ranging from simple pain Abdominal with diarrhea to occlusion or koenig...

Open access Research Article

Assessment of Urtica Aestuans Extract on Ulcer Indices and Histology of Indomethacin Induced Gastric Toxicity

Nwafor C. Charles, Ugwuishi E. Williams, Izunwanne I. Desmond & Okeke O. Cynthia · International Research Journal of Gastroenterology and Hepatology · 2022

The effectiveness of Urtica aestuans hydro-ethanolic leaf extract on ulcer indices and histopathology in Wistar rats was investigated in the current study. For this investigation, 30 rats were utilized, divided into 6 groups of 5 rats each. Groups 1 and 2 functioned as the contro...

Open access Research Article