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All published articles 232

Determining the Efficiency of Bacteriocins using Enzymes, at Varied pH, Temperature and the Ability of its Immunity Gene to Resist Antibioics Susceptibility

I. H. Abdulkarim, S. S. D. Mohammed & A. A. Orukotan · International Research Journal of Oncology · 2021

The uses of Lactic acid bacteria as probiotics have received considerable attention as a suitable alternative to antibiotics. Bacteriocins produced by LAB are used as biopreservative in foods, with a resultant reduction in the use of chemical preservatives. A typical bacteriocin...

Open access Research Article

The Place of Radiotherapy in the Management of Desmoid Tumors

Fatma Elloumi, Fatma Ajengui, Lilia Ghorbal, Mayada Bourmeche & Jamel Daoud · International Research Journal of Oncology · 2021

The management of desmoid tumors has undergone changes in recent years including active surveillance for asymptomatic and non-progressive tumors. The place of radiotherapy is contested due to significant toxicity. Radiation therapy is offered as an alternative to surgery for tumo...

Open access Research Article

Chronic Orchitis with Micro-Abscesses Simulating Testicular Neoplasm: A Case Report and Review of Literature

Friday E. Ogbetere & Sebastian A. Omenai · International Research Journal of Oncology · 2021

Scrotal pathologies are relatively common among men, with infectious causes of the testicular diseases resulting mainly from ascending infection from the urethra, although haematogenous route have also been noted. Herein, we report a case of a 37-year-old man who presented with t...

Open access Research Article

Metachronous Dual Malignancy in an Indian Albino

B. R. Kiran Kumar, Amrut S Kadam, Deepak Sharma, V. Chendil, J. Rajesh, B. K. Raghavendra & P. Shylini · International Research Journal of Oncology · 2021

Oculocutaneous albinism (OCA) is the most common inherited pigmentary disorder of the skin which is associated with impaired melanin biosynthesis. Clinical features of OCA are decreased pigmentation of the skin, hair, and eyes. The absence of melanin increases the risk of these p...

Open access Research Article

Prevalence and Pattern of KRAS and NRAS Mutations in Colorectal Cancer: A Libyan Retrospective Study

Khaled S. Ben Salah, Fatma M. Emaetig, Abdalla O. Jebriel, Nada A. Oshah, Mohamed A. Elfagieh & Ebrahim H. El Mahjoubi · International Research Journal of Oncology · 2021

About 53% of colorectal cancer (CRC) patients were reported to have the Kirsten rat sarcoma viral oncogene homolog (KRAS) gene mutations. These mutations in the KRAS gene are able to render the targeted therapy agents such as monoclonal antibodies cetuximab and panitumumab ineffe...

Open access Research Article

Triaging Women with Prior ASCUS Liquid Based Cytology (LBC) Results with Hr-HPV DNA Testing in Harare, Zimbabwe

Raymond Chibvongodze, Tafadzwa Dupwa, Lucy Muchiri & Chantal Nyirakanani · International Research Journal of Oncology · 2021

Background: ASCUS is a borderline cytopathological diagnostic category that leaves clinicians with a dilemma regarding how to manage the patient. Triaging women with prior ASCUS results with Hr-HPV testing helps to distinguish those with true neoplastic lesions from those with re...

Open access Research Article

Outlook on Genetically Engineered CAR T-Cell Therapies for Solid Tumours

Yana Pautova, Yuri Tolkunov, Luis Mendoza & Brian Churchill · International Research Journal of Oncology · 2021

T-cell-based methods using genetic engineering technology are considered the most advanced treatments in cancer therapy. Chimeric antigen receptor (CAR) T-cell therapy is an innovative immunotherapy wherein autologous T-cells are genetically modified to recognize and destroy canc...

Open access Research Article

Utility of Mucositis Predictive Tools in Patients Receiving Chemo Radiotherapy for Various Indications

A. V. S. Suresh, Rakesh Sharma, Sneha S Siripurapu, P. S. Dattatreya & C. H. Mohana Vamsy · International Research Journal of Oncology · 2021

Background: Mucositis is a debilitating and a common complication in patients receiving Chemo radiotherapy with varying incidence and severity. Certain clinical factors are associated with the incidence and severity of mucositis in different patient populations.  Early prediction...

Open access Research Article

Role of Diet and Probiotic in Prevention of Colorectal Cancer with a Review on Interplay of Pathogenesis

Tutul Chowdhury, Padmaja Deb Roy, Hasanul Islam Chowdhury & Eram Ahsan · International Research Journal of Oncology · 2021

Colorectal cancer has always been a focus for early detection by widely available screening procedures, yet it is the third common cancer worldwide. Dietary habits have a significant impact on the colonic microenvironment. Food can modify colonic microbiota composition to prevent...

Open access Research Article

A Case of Urinary Bladder Dermoid

Anupam Lahiri & Ashwini Kumar Malhotra · International Research Journal of Oncology · 2021

Dermoid cysts can be found at various sites, most common being the ovaries. However, the occurrence of dermoid cysts in the urinary bladder is an extremely rare entity. We report the case of a 54 years female, who came with complaints of white discharge with urine associated with...

Open access Research Article

A Case Series of Malignant Myelomatous Pleural Effusion with Detailed Karyotyping

Nishith Vaddeboina, A. V. S Suresh, P. S. Dattatreya & Rakesh Sharma · International Research Journal of Oncology · 2021

Primary myelomatous pleural effusion (PMMPE) is a rare presentation. It is diagnosed based on the presence of plasma cells in pleural fluid along with elevated Monoclonal protein. PMMPE is considered to have poor prognosis with reported survival of 4 to 6 months. This study repor...

Open access Research Article

MRCP for Cholangiocarcinoma and Viability of Artificial Intelligence to Oncological Care in Pakistan: A Case Report and Literature Review

Khurram Khaliq Bhinder, Ammara Tariq, Zouina Sarfraz, Azza Sarfraz, . Ameena & Zainab Malik · International Research Journal of Oncology · 2021

Introduction: Cholangiocarcinoma (CCA) is a primary malignancy arising from cholangiocytes of the biliary tract. In majority of the cases, late presentations are noted, where there is vascular encasement with perineural and lymphatic invasion. Curative resection with negative tum...

Open access Research Article

Analysis of the Influence of Age, Size, and Gender on the Relationship Reporting and Data System (ACR TI-RADS) and the Incidence of Thyroid Cancer in Surakarta between Ultrasonography Classified by American College of Radiology Thyroid Imaging

M. Ihya Ulumuddin Rahawarin, Kristanto Yuli Yarso, . Widiastuti & Akhmad Azmiardi · International Research Journal of Oncology · 2021

Background: The study aims to see if the age, tumor size and gender factors affect TI-RADS sensitivity. Ultrasonography examination (USG) plays a major role in the initial diagnosis process of a suspected thyroid tumor or cancer to evaluate thyroid nodules. ACR TI-RADS is a class...

Open access Research Article

A Prospective Observational Study of the Efficacy of Neoadjuvant Chemotherapy in Newly Diagnosed Inoperable Patients of Epithelial Ovarian Cancer

S. Janarthan Babu, Rakesh Sharma, A. V. S. Suresh, S. S Nirni, P. S. Dattatreya & A. Vindhya Vasini · International Research Journal of Oncology · 2021

Introduction: Ovarian cancer is the leading cause of death from gynecological cancers in developed countries. More than 70% of patients have Stage III – IV disease at diagnosis. The standard of care for advanced ovarian cancer is primary debulking surgery (PDS) followed by adjuva...

Open access Research Article