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Research Article Open access CC BY 4.0

Metachronous Dual Malignancy in an Indian Albino

B. R. Kiran Kumar, Amrut S Kadam, Deepak Sharma, V. Chendil, J. Rajesh, B. K. Raghavendra, P. Shylini

International Research Journal of Oncology · pp. 228–232 · Published 10 Aug 2021

Abstract

Oculocutaneous albinism (OCA) is the most common inherited pigmentary disorder of the skin which is associated with impaired melanin biosynthesis. Clinical features of OCA are decreased pigmentation of the skin, hair, and eyes. The absence of melanin increases the risk of these patients to ultraviolet rays induced malignancies. Basal cell carcinoma (BCC) and Squamous cell carcinoma (SCC) are the most common malignancies associated with OC and have been rarely reported. Metachronous malignancies in the OCA have not been reported in the literature. We report one such rare case of Metachronous Basal Cell Carcinoma of the skin and Squamous cell Carcinoma Lung in an Indian Albinism Patient.

Oculocutaneous Albinism Melanin Skin Carcinoma Genetic Disorder

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