The Adrenal Gland as a Rare Metastatic Site of Oesophageal Carcinoma:  A Case Report

Ashish Wadekar; Sunil Kumar Mallick; Rimlee Dutta; Naveen Gupta

doi:10.9734/ajcrmh/2025/v8i1268

Research Article Open access CC BY 4.0

The Adrenal Gland as a Rare Metastatic Site of Oesophageal Carcinoma: A Case Report

Ashish Wadekar, Sunil Kumar Mallick, Rimlee Dutta, Naveen Gupta

Asian Journal of Case Reports in Medicine and Health · pp. 357–362 · Published 14 Oct 2025

10.9734/ajcrmh/2025/v8i1268

Abstract

Background: Oesophageal squamous cell carcinoma (OSCC) frequently metastasizes to lymph nodes, liver, lung, bone and brain; adrenal involvement is rare and is detected incidentally or during autopsy. Case Summary: Herein, we report a case of a 42-year-old male diagnosed with moderately differentiated OSCC. On imaging, distal oesophageal lesion with a left adrenal nodule was seen. Following neoadjuvant chemoradiotherapy, the patient underwent Ivor Lewis esophagectomy with left adrenalectomy. Histopathology confirmed adrenal metastasis from OSCC. The final stage was ypT3 ypN0 ypM1 (Stage IVB). Conclusion: The present case highlights the importance of thorough metastatic workup in oesophageal cancer, as adrenal lesions may be the first or only sign of distant spread. Histopathological confirmation is crucial for guiding appropriate surgical and therapeutic decisions.

Oesophageal carcinoma Adrenal gland metastasis carcinoma squamous cell carcinoma

Cited by 0

No indexed citations yet.

Fracture of the Humeral Bone as the First Clinical Presentation of Metastatic Papillary Thyroid Carcinoma in Ibadan — shares topic coverage
Rare Presentation of Metastatic Papillary Thyroid Carcinoma with Cribiform Type in Pelvic Bones — shares topic coverage
The E1 Copper Binding Domain of Full-Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform-Specific Manner — shares topic coverage
Inhibition of Mmp-9 Expression through Nf-Kβ by Natural Compounds as a Possible Therapeutic Adjuvant Strategy in Breast Cancer: A Systematic Review — shares topic coverage
Metastasis in the Small Bowel from Primary Malignant Melanoma of the Palate: Report of an Unusual Case — shares topic coverage

Access this article

View at publisher

Cite this article

Ashish Wadekar, Sunil Kumar Mallick, Rimlee Dutta, Naveen Gupta (2025). The Adrenal Gland as a Rare Metastatic Site of Oesophageal Carcinoma: A Case Report. Asian Journal of Case Reports in Medicine and Health , 357–362. https://doi.org/10.9734/ajcrmh/2025/v8i1268

Affiliations

Ashish Wadekar — Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Sunil Kumar Mallick — Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Rimlee Dutta — Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Naveen Gupta — Department of Surgical Oncology, National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India.

Metrics

0
Views: 0
Downloads: 0
Citations: 0
Outbound

Full metrics

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

0

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.