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Research Article Open access CC BY 4.0

Advance in the Synthesis of Sulfoxides and Sulfinamides from β-Sulfinyl Esters

Xianjie Yin, Qiaoling Zhang, Qingle Zeng

Organics · pp. 173–185 · Published 19 Apr 2023

10.3390/org4020014

Abstract

Sulfoxides and sulfinamides play important roles in the pharmaceutical industry, organic synthesis and fine chemicals. This review will demonstrate that, under catalysis by transition metals, β-sulfinyl esters, as nucleophilic reagents, react with a variety of electrophilic reagents to produce sulfoxides and sulfinamides. The important prospect of the asymmetric catalytic synthesis of chiral sulfur-containing molecules in this field is described.

Chemistry Reagent Nucleophile Electrophile Catalysis Enantioselective synthesis Organic synthesis Combinatorial chemistry

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