A Review on Antibiotic Resistance in Chronic Kidney Disease (CKD) Patients Undergoing Dialysis

Abstract

Antibiotic resistance is a worldwide health threat, especially within high-risk groups, including chronic kidney disease (CKD) patients who are on dialysis. These patients are at high risk for developing the infections because of altered immunity, frequent contact with healthcare facilities, and invasive procedures and owing to these nosocomial infections these patients suffer from additional challenges. The overuse and misuse of antibiotics in this population additionally increases their risk of multidrug-resistant (MDR) infections, which place notable challenges on clinical management. This review aims to identify the burden and consequences of antibiotic resistance among CKD patients on dialysis, with an emphasis on need for robust infection control measures especially at healthcare setups, targeted surveillance programs, and innovative approaches to mitigate this life threatening antibiotic resistance in CKD patients undergoing dialysis. By addressing these challenges, this review aims to provide a comprehensive understanding of the issue and identify possibilities for improving the health outcomes in these high-risk groups.