Skip to content
Research Article Open access CC BY 4.0

Weight Gain as Tuberculosis Treatment Regimen Progresses in Patients Receiving Antituberculosis Therapy

A. N. Umo, N. O. Umoh

Asian Journal of Medicine and Health · pp. 1–5 · Published 10 Dec 2016

10.9734/AJMAH/2016/29090

Abstract

Background: Tuberculosis (TB) has been known to be one of the most frequent underlying causes of wasting worldwide and this has however remained poorly studied and understood. Methods: Pattern of weight gain during tuberculosis treatment in Ekpene Obom, Nigeria was assessed between January 2012 and December 2014. The 389 patients, who attended the TB clinic within this period, made up of 171(44%) males and 218(56%) females were used in this study. Results: Patients had an average weight of 44.5kg at the time their infection was diagnosed. The percentage weight increment within this period was 12.1%. Yearly sex-specific percentage weight increment in 2012, 2013 and 2014 respectively for the males were 12.4%, 11.4% and 11.9% while it was 12.5%, 11.6% and 12.7% for the females within the same period. Similarly, within specific age groups, it also revealed an increment of 11.8%, 16.0%, 14.7%, 13.4%, 10.8% and 10.6% for 11-20 years, 21-30 years, 31-40 years, 41-50 years, 51-60 years and 61-70 years respectively. The females were seen to have higher body weights than the males. Conclusion: This study has shown that clinical recovery does not guarantee immediate restoration of body weight and also confirms weight gain to be an unreliable indicator of overall treatment response in anti-tuberculosis therapy.  

Weight gain tuberculosis treatment Nigeria

References (12)

  1. 1 Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 [DOI]
  2. 2 The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals.
  3. 3 Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study [DOI]
  4. 4 A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status [DOI]
  5. 5 Energy expenditure of stunted and nonstunted boys and girls living in the shantytowns of São Paulo, Brazil [DOI]
  6. 6 Tuberculosis, malnutrition and wasting [DOI]
  7. 7 Nutrient partitioning during treatment of tuberculosis: gain in body fat mass but not in protein mass [DOI]
  8. 8 Bodyweight gain to predict treatment outcome in patients with pulmonary tuberculosis in Peru.
  9. 9 Weight, body composition and handgrip strength among pulmonary tuberculosis patients: a matched cross-sectional study in Mwanza, Tanzania [DOI]
  10. 10 Body Composition Among HIV-Seropositive and HIV-Seronegative Adult Patients with Pulmonary Tuberculosis in Uganda [DOI]
  11. 11 Lack of Weight Gain and Relapse Risk in a Large Tuberculosis Treatment Trial [DOI]
  12. 12 Alteration In The Levels Of Serum Micronutrients In Tuberculosis Patients

Cited by 2

Showing 1 of 2 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

62

Page views

0

PDF downloads

31

Outbound clicks

2

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.