Albumin/Ag Nanoparticles Synthesized by Using UV-Irradiation and Estimation of Their Antibacterial Activity

Abstract

Nano-scale (less than 100 nm) materials have received wide attention because of their rare properties that differ significantly from a bulk sample of the same material. In this research, a physical irradiation method by using UV lamp was established for preparation nanoparticles colloids of silver nanoparticles (Ag-NPs) with an eco-friendly stabilizer (Albumin). The preparation process was carried out using silver nitrate (AgNO3) in aqueous albumin at room temperature. The effects of UV-irradiation time and the concentrations of Ag+ and albumin on the particle size have been investigated. Moreover, the antibacterial effect of the Ag/Albumin nanoparticles has been tested. The results showed that, the UV–irradiation can influence the Ag-NPs size, which the of Nps  decreases with the UV–irradiation increases. The morphological study demonstrated well-dispersed spherical Ag-NPs with an average diameter of about 29 nm at the optimum conditions. The antibacterial results exhibited a significant inhibitory effect for the Ag-NPs that synthesized in this work. The current fabrication method of the silver nanoparticles colloid could be extended to other metals such as Cu- Nps and may possibly find various additional applications.