Effect of Moringa oleifera Ethanolic Leaf Extract for the Management of Hepatotoxicity and Nephrotoxicity in Mice
Arshia Tariq, Umbreen Shahzad, Muhammad Shah Jahan, Zahid Abbas, Asia Rasool, Phoebe Nemenzo Calica
Journal of Complementary and Alternative Medical Research · pp. 1–10 · Published 15 Dec 2018
10.9734/JOCAMR/2018/44623Abstract
Moringa oleifera is a valued medicinal plant. It is a rich source of nutrients, amino acid, antioxidants, anti-ageing and anti-inflammatory compounds. This study was carried out to assess the effect of the ethanolic extract of Moringa oleifera leaves on tetrachloride CCL4 induced liver damage and gentamycin induced kidney damage in albino mice. Twenty-eight (28) mice were divided into seven groups subjected to the different treatments. Results from the serum enzyme assay revealed that the Moringa oleifera leaf ethanolic extract reduced the activities of the hepatic and renal enzymes voz: ALP, AST, ALT, blood urea nitrogen and creatinine. Moringa oleifera leaf extracts showed significant amelioration of experimentally induced hepatotoxicity and nephrotoxicity which enhanced the recovery from hepatic damage induced by CCL4 and renal damage induced by gentamycin.
Cited by 1
W. Arozal, Emni Purwoningsih, H. J. Lee · Frontiers in Nutrition · 2022
Related research
- Ameliorative Potentials of Yoyo Bitters and Aqueous Leaf Extract of Moringa oleifera in Arsenite Induced Inflammatory Dysfunctions in Male Wistar Rats — shares topic coverage
- Morphological and Biochemical Effects of Aqueous Extract of Moringa oleifera Leaf on Cobalt Chloride-Induced Cerebral Damage in Adult Wistar Rats — shares topic coverage
- Antimicrobial Activity of Moringa oleifera Leaf against Isolates of Beef Offal — shares topic coverage
- Phytochemical Profiling and Anti-MRSA Activity of Extracts from Moringa oleifera Lam. and Senna occidentalis (L.) Link Cultivated under Organic Conditions — shares topic coverage
- Influence of Moringa oleiferea Seed Meal and Yam Blend in Body Weight and Glucose Level of Alloxan Induced Diabetes Mellitus Male Albino Rats — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.