Surveillance of Surgical Site Infection & Burnt Skin Infection in High-Risk Area and Documenting its Spread to Give Prevention Guidelines for Resource-Constrained Institute

Abstract

Purpose: Our study aims to analyze multiple factors, such as finding the prevalence of SSI (surgical site infection) and BSI (burn skin infection) infections, including incidence rates and hospital-wide rates, to find the antibiotic profile, including multidrug-resistant organisms like CRE (carbapenem-resistant Enterobacteriaceae) and ESBL (Extended Spectrum Beta Lactamses). Methods: We conducted a cross-sectional study in a hospital setting. The study included all patients from high-risk ICUs, surgical wards, and burn wards during the study period who had clinical symptoms and positive culture results. The antibiotic susceptibility testing was performed using the Kirby-Bauer disk diffusion method, and the results were interpreted in accordance with CLSI recommendations. Results: The SSI and BSI incidence rates (per 1000 hospital days) were 90.90 and 41.66, respectively. The hospital-wide SSI rate was 29.94, while the BSI rate was 25. The frequency was discovered to be twice as common in males as females. In our study, we isolated Acinetobacter baumannii (31.39%), Pseudomonas aeruginosa (20.93%), E. coli (17.44%), Klebsiella pneumoniae (13.95%), CONS (10.46%), Enterobacter species (4.65%), and Klebsiella oxytoca (1.16%). The highest ESBL production rates were found in E. coli (40%), P. aeruginosa (27.77%), and K. pneumoniae (33.33%). Conclusion: Our study found that if infection control methods are implemented and followed correctly, the incidence rates of infections occurring during patient hospitalizations can be reduced. Proper monitoring is required to control infections in post-operative patients as well as infections in patients with burn wounds. An antimicrobial stewardship policy should be considered to prevent antibiotic resistance in the organism, ensure effective treatment of patients admitted to health-care institutions, and reduce patients' economic burden. Beta-lactamases) in high-risk areas like burn wards and surgical wards, which would help to come to appropriate.