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Research Article Open access CC BY 4.0

Novel Association between Gemfibrozil and Dyslipidemia: A Case Report

Deena M. S. Barrouq, Tareq Irshaidat

Asian Journal of Medicine and Health · pp. 38–43 · Published 8 Oct 2020

10.9734/ajmah/2020/v18i1030250

Abstract

Dyslipidemia is a risk factor in many health complications, among them is hypertension. Case: This report presents a case of a poorly controlled dyslipidemia that could not be managed by medications. A surprisingly and an unexpected factor interfered; the triglyceride-lowering medication caused a significant increase in the appetite toward fat-rich food items which opposed its intended purpose. Methodology: A dietary intervention and an uncommon drug dose modification were necessary. Results: The personally designed protocol led to a significant overall improvement and was successful in adjusting the biochemical parameters especially the plasma triglycerides and the total cholesterol and was effective in reversing hypertension and a pre-diabetic state to safer values. Conclusion: This is the first characterized case in the literature on the involvement of gemfibrozil in poor management of dyslipidemia.

Gemfibrozil dyslipidemia triglycerides total cholesterol hypertension low-fat diet.

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