In vitro Evaluations of Anodic Spark Deposited AZ91 Alloy as Biodegradable Metallic Orthopedic Implant

Mehdi Razavi; Mohammadhossein Fathi; Omid Savabi; Daryoosh Vashaee; Lobat Tayebi

doi:10.9734/ARRB/2014/10173

Research Article Open access CC BY 3.0

In vitro Evaluations of Anodic Spark Deposited AZ91 Alloy as Biodegradable Metallic Orthopedic Implant

Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi, Daryoosh Vashaee, Lobat Tayebi

Annual Research & Review in Biology · pp. 3716–3733 · Published 5 Jul 2014

10.9734/ARRB/2014/10173

Abstract

Surface treatment of Mg alloys is a major approach for its enhanced use as orthopedic implants. In this paper, the in vitro bioactivity, mechanical stability and cytocompatibility of the AZ91 Mg alloy coated by anodic spark deposition (ASD) method are studied. The cytocompatibility behavior is examined by culturing L-929 fibroblast on the surface of the uncoated and ASD-coated AZ91 Mg substrates. The results showed that the corrosion resistance, in vitro bioactivity, mechanical stability and cytocompatibility of biodegradable Mg alloy were improved by ASD coating. Reduction of the degradation rate by ASD coating not only created a relatively stable interface for the cell adhesion and growth, but also arrested the release of corrosion products to reduce the cytotoxicity, hence, resulting in the enhanced cytocompatibility.

Biodegradable magnesium alloy coating; in vitro evaluations L-929 fibroblast cells biomedical applications

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Mehdi Razavi, Mohammadhossein Fathi, Omid Savabi, Daryoosh Vashaee, Lobat Tayebi (2014). In vitro Evaluations of Anodic Spark Deposited AZ91 Alloy as Biodegradable Metallic Orthopedic Implant. Annual Research & Review in Biology , 3716–3733. https://doi.org/10.9734/ARRB/2014/10173

Affiliations

Mehdi Razavi — Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran and Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran and School of Materials Science and Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA and School of Electrical and Computer Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA.
Mohammadhossein Fathi — Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran and Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Omid Savabi — Torabinejad Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Daryoosh Vashaee — School of Electrical and Computer Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA.
Lobat Tayebi — School of Materials Science and Engineering, Helmerich Advanced Technology Research Center, Oklahoma State University, Tulsa, OK 74106, USA and School of Chemical Engineering, Oklahoma State University, Stillwater, OK 74078, USA.

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