Skip to content
Research Article Open access CC BY 3.0

Uremic Encephalopathy with Basal Ganglia Lesions in a Diabetic Predialysis Patient

Ye Na Kim, Ho Sik Shin, Yeon Soon Jung, Hark Rim

Journal of Advances in Medicine and Medical Research · pp. 249–254 · Published 19 Jan 2013

10.9734/BJMMR/2013/2068

Abstract

Syndromes associated with acute bilateral lesions of the basal ganglia in diabetic uremic patients are uncommon, and usually have reversible clinical and imaging findings. Such syndromes are seen almost exclusively in patients with diabetes mellitus and renal failure. Previously reported cases have described diabetic men with uremia on dialysis. Here, we report a case of uremic encephalopathy with lesions of the basal ganglia in a diabetic predialysis patient. A 44-year-old man with uremic encephalopathy presented with dysarthria, chorea, and right upper extremity paresthesia. Magnetic resonance imaging of the brain showed classic findings of hyper intensity in the bilateral basal ganglia. The patient had no family history of psychiatric or neurological disease. Laboratory findings revealed elevated levels of blood urea nitrogen, creatinine, and glucose. Haloperidol and ropinirole therapy was continued, resulting in significant improvement without dialysis. The patient recovered from his episode without apparent sequelae. 

Diabetes mellitus uremic encephalopathy basal ganglia predialysis.

References (17)

  1. 1 Neurological complications in renal failure: a review [DOI]
  2. 2 Dystonia and chorea in acquired systemic disorders [DOI]
  3. 3 Central nervous system complications of diabetes mellitus — a perspective from the blood–brain barrier [DOI]
  4. 4 The syndrome of acute bilateral basal ganglia lesions in diabetic uremic patients [DOI]
  5. 5 Neurologic disorders in renal failure [DOI]
  6. 6 Acute movement disorders with bilateral basal ganglia lesions in uremia [DOI]
  7. 7 Reversible MRI and CT findings in uremic encephalopathy [DOI]
  8. 8 BASAL GANGLIA NEUROTOXINS [DOI]
  9. 9 Parkinsonism with basal ganglia lesions in a patient with uremia: Evidence of vasogenic edema [DOI]
  10. 10 Diffusion‐weighted magnetic resonance imaging in the syndrome of acute bilateral basal ganglia lesions in diabetic uremia [DOI]
  11. 11 Acute Bilateral Basal Ganglia Lesions in Patients With Diabetic Uremia: An FDG-PET Study [DOI]
  12. 12 The syndrome of bilateral basal ganglia lesions in diabetic uremic patients presenting with a relapsing and remitting course: a case report.
  13. 13 Acute Chorea with Bilateral Basal Ganglia Lesions in Diabetic Uremia [DOI]
  14. 14 Acute reversible parkinsonism in a diabetic-uremic patient [DOI]
  15. 15 Diabetic Renal Failure and Serum Accumulation of the Creatinine Oxidative Metabolites Creatol and Methylguanidine [DOI]
  16. 16 Concentration of Striatal Tyramine and Dopamine Metabolism in Diabetic Rats and Effect of Insulin Administration [DOI]
  17. 17 Diabetic nephropathy with acute symmetrical changes in the basal ganglia regions [DOI]

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

52

Page views

0

PDF downloads

23

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.