Hallux Ischemia Observed during the Ergotamine Taking
Raja Amri, Rabie Ayari, Rami Triky, Fatma Ben Dahmane, Mohamed Ali Sbai
Asian Journal of Research in Surgery · pp. 81–84 · Published 18 May 2020
Abstract
Arteriopathies due to drug-administration have been described. However, the data is insufficient. Ergotism is caused by ergotamine derivatives intake. It can lead to arterial spasms, causing limb claudication and even distal necrosis in some cases. We report a 42-year-old female patient with a 2-year history of ergot derivatives treatment for migraine attacks. She presented with acute ischemia of the left hallux. She did not take any concomitant medications. Blood test was normal, as well as the arterial Doppler ultrasound of the lower limb. No other cause that could explain this ischemia was present. Discontinuation of ergotamine and vasodilator treatment resolved the ischemia, without sequelae. Physicians should be aware that ergotamine may cause ischemia. Stopping ergotamine is important.
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