A Comprehensive Review of Treatment Options of OSMF along with Future Developments

Abstract

Oral potentially malignant disorders(opmds) are defined by WHO as “the risk of malignancy being present in a lesion or condition either at the time of initial diagnosis or at a future date.” OSMF(oral submucous fibrosis) being an opmd carries a very high chance of cancer if left untreated or undiagnosed in the long run. However there are no definitive guidelines for the treatment of  osmf ranging from conservative(non invasive) options to radical surgical options. The primary objective of this article was to critically analyse the studies regarding the treatment options for osmf and to provide the clinician in a comprehensive manner all the available options in one place. A thorough electronic search was carried for relevant articles published until  January 2022. Thirty two studies were included in this review after initial screening of 340 articles. The review found that inspite of there being so many available treatment options for osmf no sole therapy can be successfully advocated for the complete resolution of the disease therefore the clinician should rely on a combination of treatment options to achieve good results along with improving patient outcomes and overall quality of life thereby significantly reducing morbidity and mortality among patients suffering from osmf.