The Impact of Next-generation Sequencing on Biotechnology: A Review of Current Applications
Lukram Sushil Singh, Gowhar Iqbal, Arya Singh, Maharshi Limbola, Ad Viral Kumar
Journal of Scientific Research and Reports · pp. 91–97 · Published 25 Oct 2024
10.9734/jsrr/2024/v30i112536Abstract
Since sequencing was developed by Sanger and Gilbert in 1977, various sequencing methods have been introduced in biotechnology to sequence DNA. Next-generation sequencing is a novel high-tech method where the sequencing of thousands of DNA molecules can be done in parallel to generate enormous amounts of genetic data within one experiment. This novel generation of sequencing superseded conventional techniques like Sanger sequencing with parallelization to achieve rapid genome sequencing at minimum costs. In this chapter, we highlighted various applications of using NGS in different fields, such as genomic research, clinical diagnostics, metagenomics, water quality assessment, and food authenticity. Besides, NGS could identify genetic variations, diagnose diseases, and assess food quality with high accuracy, rapidity, and specificity.
Cited by 4
Henry Sutanto, Laras Pratiwi, Pradana Zaky Romadhon · Human Genetics · 2025
Laras Pratiwi, Galih Januar Adytia, Henry Sutanto · Human Gene · 2025
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