The Effects of Lifestyle Modofications on Sperm DNA Fragmentation Index

Abstract

Background: Most of the men go through infertility due to DNA defects in sperm. DNA defects in sperm can be measured by sperm DNA fragmentation test. Sperm DNA splitting have been correlated with sperm viability and its major impact on male infertility. Many studies have shown that men with disturbed lifestyle habits such as smoking ,alcoholic consumption ,poor diet have very poor DNA quality compared to the men with proper habits like good diet , exercise and a well maintained routine. There has been many tests to measure the DNA breakage after conducting proper semen examination and infertility duration. This can be treated with proper medications and regular exercise. Objectives: 1. To predict the reason for male infertility by evaluating routine semen parameters. • To study the effects of daily lifestyle habits associated with SDF in patients who are not fertile. • To investigate the amount of sperm DNA splitting in men who are not fertile. 4.To investigate the association between DFI and semen quality, between DFI and IVF, between DFI and IUI. 5.To estimate the outcomes of sperm DNA fragmentation index and allow the patients to seek post infertility treatments. Methods: This non-invasive methodology includes recording of treatment history and the indications of infertility. Proper counselling for the patients were done. A proforma were filled along with their consent showing the accuracy of smoking, alcohol consumption, stress levels and other mentioned factors and hence calculating the sperm breakage levels.