The Effect of Endometrial Scratching before Embryo Transfer in Woman with History of Implantation Failure in Previous Intracytoplasmic Sperm Injection Cycle, Clinical and Biological Study

Abstract

Background: The gain of endometrial scratching in people has been offered with the aid of clinicians as a potential of growing endometrial receptivity was once at the beginning stated as a serendipitous discovering because a high pregnancy price was once located in IVF female who had undergone repeated endometrial biopsies at some stage in their preceding herbal menstrual cycle. The goal of this work used to be to consider the impact of endometrial scratching earlier than fresh or frozen embryo switch on clinical pregnancy fee in girls with records of implantation failure after one or more Intracytoplasmic sperm injection cycle(s) and to predict its cost based on measuring the level of peripheral Natural Killer Cells (cd56). Methods: This potential randomized learn about was carried out on 60 ladies with records of one or more implantation failure of ICSI cycle, and regular uterine cavity. Patients were divided into two equal groups: an experimental group A and a manage group B. All sufferers were subjected to history taking, clinical examination, investigations for infertility, serum Natural killer cells CD56 measure and hormonal profile. Results: There was once giant difference in CD56 size between girls who obtained pregnant (decreased CD56) and those who now not got pregnant (increased CD56) in team A .Clinical Pregnancy rate was higher in group A after endometrial scratching was done. Conclusions: Performing harm profiling at the time of implantation window (CD56 measurement) ought to assist in deciding on sub-groups of infertile patients who would gain from a targeted intervention.