Synthesis, Anti-microbial, Flameretardance and Anti-corrosive Activity of Some New Heterocycles Incorporating Coumarin moiety
S. M. Mohamed, Nadia T. A. Dawoud, N. Abd El-Khalik, Wafaa. M. Mazen, Z. I. El Bailey
International Research Journal of Pure and Applied Chemistry · pp. 23–37 · Published 8 Apr 2020
10.9734/irjpac/2020/v21i430163Abstract
In the present study a series of novel heterocyclic compounds (2-16) incorporating coumarin moiety was synthesized. The newly synthesized compounds were elucidated on the basis of elemental analysis, spectral data, were tested for in-vitro antibacterial activity against Staphylococcus aureus, Bacillus subtilis (Gram-positive bacteria), Salmonella typhimurium, Escherichia coli (Gram-negative bacteria) and Candida albicans, Aspergillus fumigatus (fungi). Coumarin derivatives (1,6,16) were chosen to evaluate the anti-corrosion, flame retardant properties. The results clearly showed that, the incorporation of coumarin derivatives into epoxy coating have led to improve the flame residency, corrosion resistance, and mechanical properties of investigated coating and confirmed that these new developed varnishes have an excellent properties as flame resistance and anticorrosive for mild steel.
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