Takayasu Arteritis with MOG Antibody Disease: A Rare Overlap

Abstract

Takayasu arteritis a rare chronic granulomatous vasculitis that causes arterial stenosis, occlusion, and systemic effects, mostly affects the aorta and its primary branches. The illness, which can produce a variety of neurological and systemic symptoms, most commonly affects young women. We report a 29-year-old female patient with neurological symptoms who was diagnosed with Takayasu arteritis linked to myelin oligodendrocyte glycoprotein antibody disorder (MOGAD). The clinical evaluation's findings of hypertension, limb weakness, and neurological deficits prompted further diagnostic investigations, such as laboratory tests and cerebrospinal fluid analysis. Imaging and laboratory results supported the diagnosis of Takayasu arteritis with neurological damage. The patient was given high-dose corticosteroid therapy, antihypertensive drugs, immunomodulatory drugs, and supportive care. The patient showed clinical improvement, and their neurological problems normalized during their hospital stay. This case highlights the need to identify Takayasu arteritis early, particularly when neurological signs are present, and the importance of interdisciplinary care in improving clinical outcomes.