Synthesis of Cannabigerol and Cannabigerol Derivatives

References (26)

1. 1 Connor, 2021, Cannabis use and cannabis use disorder [DOI]
2. 2 Mechoulam, R. (2019). Cannabinoids as Therapeutic Agents, CRC Press. [DOI]
3. 3 Lu, 2021, Review of the endocannabinoid system
4. 4 Salha, 2023, Bioactivity of the cannabigerol cannabinoid and its analogues—The role of 3-dimensional conformation [DOI]
5. 5 Jastrzab, A., Jarocka-Karpowicz, I., and Skrzydlewska, E. (2022). The origin and biomedical relevance of cannabigerol. Int. J. Mol. Sci., 23. [DOI]
6. 6 Cabrera, 2021, The anti-inflammatory effects of cannabidiol and cannabigerol alone, and in combination [DOI]
7. 7 Borrelli, 2013, Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease [DOI]
8. 8 Gugliandolo, A., Pollastro, F., Grassi, G., Bramanti, P., and Mazzon, E. (2018). In vitro model of neuroinflammation: Efficacy of cannabigerol, a non-psychoactive cannabinoid. Int. J. Mol. Sci., 19. [DOI]
9. 9 Piscitelli, 2015, The endocannabinoid system and its modulation by phytocannabinoids [DOI]
10. 10 Longhi Bitencourt, E., Flix Ventura, D., and Fernandez Costa, M. (2020). South American values of the optical straylight function. Vision, 4. [DOI]
11. 11 Ramer, 2013, COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells [DOI]
12. 12 Borrelli, 2014, Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a cannabis-derived non-psychotropic cannabinoid [DOI]
13. 13 Brand, S., Winkler, M., and Götz, M.R. (2020). Synthesis and Purification of Cannabigerol and Its Application. (WO2020249184), Patent.
14. 14 Baek, 1985, Boron trifluoride etherate on alumina—A modified Lewis acid reagent. An improved synthesis of cannabidiol [DOI]
15. 15 Jentsch, 2020, Efficient synthesis of cannabigerol, grifolin, and piperogalin via alumina-promoted allylation [DOI]
16. 16 Seccamani, 2021, Photochemistry of cannabidiol (CBD) revised. A combined preparative and spectrometric investigation [DOI]
17. 17 Kuman, 2008, Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities [DOI]
18. 18 Nicholson, 1994, Cyclization reactions leading to β-hydroxyketo esters [DOI]
19. 19 Focella, 1977, A simple and practical synthesis of olivetol [DOI]
20. 20 Djura, 1976, Depsidone synthesis. III Grayanic acid [DOI]
21. 21 Abduahadi, 2025, An improved iodine-catalyzed aromatization reaction and its application in the synthesis of a key intermediate of cannabidiol [DOI]
22. 22 Saimoto, H., Kita, K., Yabu, Y., and Yamamoto, M. (2012). Preparation of Novel Dihydroxybenzene Derivatives and Antiprotozoal Agent Comprising Same as Active Ingredient. (WO2012060387), Patent.
23. 23 Curtis, 2021, Syntheses of amorfrutins and derivatives via tandem Diels-Alder and anionic cascade approaches [DOI]
24. 24 Shoyama, 1975, Cannabichromevarin and cannabigerovarin, two new propil homologues of cannabichromene and cannabigerol [DOI]
25. 25 Saimoto, 1986, A general highly efficient access to prenylated phenolic natural products. Synthesis of colletochlorins B and D [DOI]
26. 26 McNulty, 2021, A catalytic, oxidative synthesis of olivetol, methyl olivetolate and orthogonally protected methyl ether derivatives [DOI]

Cited by 2

Showing 1 of 2 known citations — external sources report more than can currently be individually listed.

Related research

• A Novel Catalytic Synthesis of Flavones under Autoclave Conditions and Comparative Study of Anti-cancer Activity — shares topic coverage
• Thermostability and in-vitro Antibacterial Activity of Aqueous Extracts of Tetrapleura tetraptera Pods on Multidrug Resistant Clinical Isolates — shares topic coverage
• Acute Toxicity, Phytochemistry and Anti-diarrheal Effects of Celtis integrifolia Lam. Aqueous Leaf Extract in Wistar Albino Rats — shares topic coverage
• Understanding the Reactivity of Trimethylsilyldiazoalkanes Participating in [3+2] Cycloaddition Reactions towards Diethylfumarate with a Molecular Electron Density Theory Perspective — shares topic coverage
• Understanding the Origin of the Regioselectivity in Non-Polar [3+2] Cycloaddition Reactions through the Molecular Electron Density Theory — shares topic coverage