Synthesis, Characterization and Antimicrobial Activity of Metal Complexes of N-(4-methoxybenzylidene) Isonicotinohydrazone Schiff Base
Md. Sajjad Hossain, Farzana Khanm Camellia, Nayon Uddin, Md. Kudrat-E-Zahan, Laila Arjuman Banu, Md. Masuqul Haque
Asian Journal of Chemical Sciences · pp. 1–8 · Published 3 Apr 2019
10.9734/ajocs/2019/v6i118987Abstract
Two complexes of Cu(II) and Ni(II) with the ligand N- (4-methoxybenzylidene) isonicotinohydrazide, having the formula [M(La)2]2+ (M = Cu(II) and Ni(II)) were synthesized. The ligand was synthesized by the condensation of isonicotinic acid hydrazide (isoniazid) with 4- methoxybenzaldehyde (p- anisaldehyde). The complexes were characterized by FTIR, UV-Vis spectroscopy, molar conductivity, magnetic susceptibility and evaluated for their in vitro antibacterial activity against human pathogens like gram negative Escherichia coli (E. coli) and gram positive Bacillus cereus (B. cereus)strains. The results indicate that all complexes consist of N and O coordination with metals has better antimicrobial activity.
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