Synovial Fluid Analysis and Biopsy in Diagnosis of Joint Diseases

Abstract

Worldwide, Arthritis is a communal clinical incidence of joints, and very predominant chronic disease in India. To evaluate to affect 1% of world’s adult population. Biopsies of Synovial fluid are being done as an adjuvant technique to assist in the diagnosis of arthritis. It offers a non-invasive method to diagnose any condition of the joint like traumatic, non-inflammatory/ inflammatory. Cytomorphological examination of Synovial fluids received   in   the   Department   of   Pathology, Sree Balaji Medical College and Hospital, Chennai. To examine the   gross,   microscopic, biochemical and    microbiologic variations in   the   synovial fluid in percutaneous synovial biopsy along with synovial fluid analysis was studied in 102 enrolled cases of arthritis. The liquefied was subjected to physical, biochemical and cytological analysis. To correlate synovial fluid cytology with biopsies whenever possible to increase the accuracy   of diagnosis. Synovial fluid analysis plays an important role in categorizing various arthritis and thereby helps in arriving at a diagnosis early.