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Research Article Open access CC BY 4.0

Study of Placental Chorangiosis in a Tertiary Care Centre

M. Vanishree, Sonti Sulochana, Martin M. S. Salin

Journal of Pharmaceutical Research International · pp. 92–97 · Published 29 Dec 2021

10.9734/jpri/2021/v33i63B35256

Abstract

Background: Chorangiosis is a condition in which the number of vascular channels in the noninfarcted, nonischemic areas of the placenta increases dramatically. Chorangiosis rarely occurs in normal pregnancies. Aims: To study the demography, maternal and fetal causes of chorangiosis. Study Design: A retrospective descriptive study. Place and Duration of Study: Total of 73 patients with chorangiosis were studied in Department of Pathology Saveetha Medical College,during the period ofAugust 2020 and February 2021. Methodology: Study included 73 patients of placental chorangiosis.The clinical history and demographic data was obtained from the patient’s medical records.Thematernal and fetal causes were studied, and clinico-histopathological correlation was done. Results: This study includes 73 postnatal women,of whichthe rate of cesarean section was noted to be 69.8% and the mean value were obtained showed mean gestational age of 37.5 weeks, 70 live births and 3 neonatal deaths; mean placental weight is 480 grams and birth weight 3970grams.The mean 1 minute and 5 minutes APGAR score is reduced indicatingdisturbance in fetal vitals immediately after birth. Conclusion: Chorangiosis is a rare illness, which is associated with an increased risk of prenatal and neonatal morbidity and mortality.So, it should be regarded as a key prognostic indicator of poor pregnancy outcomes and should be essentially reported in the histopathological evaluation.

Chorangiosis maternal hypoxia placental weight birth weight APGAR score

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