Scientometric Study on Dyslipidaemia

Abstract

Dyslipidaemia an ever increasing menace emerging out of present lifestyle, is one of the major risk factors for developing Cardio-vascular abnormalities like Coronary Artery Disease (CAD), Myocardial infarction (MI), Cardiac arrest and is often associated with other metabolic disorders. Clinicians across the globe are trying hard to combat it. We have presented a Scientometric analysis of dyslipidaemia which includes Ayurvedic perspective also. Objective: In this study we intended to study detailed Scientometric and Bibliometric study on dyslipidaemia literature. Materials and methods: The data was collected using databases of Science- direct and Scopus, using the keywords ‘Dyslipidaemia’, ‘Dyslipidaemia in Ayurveda’, ‘Dyslipidaemia in India’,‘Medoroga in Ayurveda’ and ‘Medoraga in India’. Results: A total of 85,500 items were retrieved from ‘science direct’ website, where majority of them were research articles and maximum publications were from the last decade indicating the recent enhancement in prevalence and awareness. A volley of research papers have come up with multiple approaches which include modern pharmacological measures, Ayurveda remedies and other herbal medicines along with non-pharmacological approaches like Yoga and Pranayama. Newer therapeutic agents like Ezetimibe, proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies, PCSK9 small interference RNA (siRNA), and bempedoic acid, when added to the commonly used statin therapy have shown additional improvement to CV outcomes. Recent advances have come up with hepatocyte-specific targeting modifications and have shown promising lipid lowering effects. Conclusion: Our study was probably the first such kind of work in field of dyslipidaemia which includes publications related to Ayurveda and other herbal remedies also. It shows the ever rising trends in the publications related to dyslipidaemia and its relation to other metabolic disorders in recent years. The major concern is the progression in cases of dyslipidaemia and its cardiovascular outcomes despite of having substantial research work and awareness in different streams of medicine. We must focus on the multifactorial approach encouraging behavioural, dietary and pharmacological control of cholesterol and sensitize the masses about its serious consequences. A cumulative approach including modern advances with much safer herbal remedies and practice of Yogasana and Pranayama is the need of hour and may probably bring the best solution.