Evaluation of Anticancer, Thrombolytic and Antimicrobial Activities of Heliotropium indicum (Indian turnsole)

Abstract

This research objective was to investigate some in vitro properties of methanol-extracted plant extracts of Heliotropium indicum (Indian turnsole). The primary method of assessment for the methanolic extract of Heliotropium indicum (MEHI) was investigated for phytochemical screening. It was determined to look into the plant's potential for in vitro activities, such as anticancer, thrombolytic and antimicrobial activity due to the pharmaceutical interest in its component parts. Phytochemical screening was performed utilizing a battery of test reagents. Anticancer, thrombolytic and antimicrobial activities were measured at various doses using the Cell Viability Assay, Clot Lysis Assay, the Disk Diffusion Method. The findings of research on MEHI's phytochemical screening showed the presence of a wide range of various phytochemical components. Mild anticancer activity was found in MEHI and at the dose of 1000µg/mL the zone of inhibition was 29.45%, while antibacterial action ranged from 6 mm to 18 mm zones of inhibition. Comparatively, this herb has quite powerful thrombolytic action. Significant antibacterial activity has also been shown by MEHI. To wrap it up, it is clear that this plants phytochemical can be used for wide range of drug discovery field due to its potent pharmacological actions.